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- W2911504148 abstract "Purpose: Pancreatic cysts represent varying degrees of malignant potential. Because of the limited ability to predict the precise nature of these lesions, surgical resection is often advised. The aim of this study was to identify clinicopathologic features that correlate with malignant potential of surgically resected pancreatic cysts. Methods: Using available Gastrointestinal Pathology and Surgical Oncology databases, we retrospectively reviewed all surgical resections of pancreatic cysts performed at The Mount Sinai Hospital from August 1995 to June 2006. We recorded patient characteristics, presenting symptoms, and preoperative imaging. Among a total of 74 patients, the medical records of 63 patients were available. Cysts were categorized as benign (N = 35), premalignant (N = 22), or malignant (N = 17). Results: Benign, premalignant, and malignant cysts occurred in 47.3%, 29.7%, 23.0% of resected lesions, respectively. After excluding pseudocysts, we found that patients with premalignant/malignant pancreatic cysts were more likely to be older and to demonstrate pancreatic duct dilatation on pre-operative imaging. Malignant cysts were significantly more likely to be associated with jaundice, to occur in the head or neck of the pancreas, and to have ductal dilatation on preoperative imaging (Table 1). Malignant cysts also demonstrated a trend toward increased likelihood of being symptomatic (P < 0.1).Table 1: Comparison of Nonmalignant and Malignant Pancreatic CystsConclusion: In this retrospective study, nearly half of pancreatic cyst resections were performed for benign entities. Ductal dilation occurred more commonly in premalignant and malignant cysts. Malignant cysts were associated with clinical symptoms, jaundice, and location in the head/neck. These factors may provide physicians with an improved ability to discriminate between benign, premalignant, and malignant pancreatic cysts. Using a newly established Pancreatic Neoplasia Database, we hope ultimately to better identify appropriate patients for surgical resection for pancreatic cystic lesions." @default.
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- W2911504148 date "2007-09-01" @default.
- W2911504148 modified "2023-09-25" @default.
- W2911504148 title "Clinicopathologic Features of Surgically Resected Pancreatic Cystic Lesions" @default.
- W2911504148 doi "https://doi.org/10.14309/00000434-200709002-00199" @default.
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