Matches in SemOpenAlex for { <https://semopenalex.org/work/W2911520912> ?p ?o ?g. }
- W2911520912 endingPage "531" @default.
- W2911520912 startingPage "525" @default.
- W2911520912 abstract "BackgroundThe efficacy of dexamethasone in extending the duration of local anaesthetic block is uncertain. In a randomised controlled triple blind crossover study in volunteers, we tested the hypothesis that neither i.v. nor perineurally administered dexamethasone prolongs the sensory block achieved with ropivacaine.MethodsUltrasound-guided ulnar nerve blocks (ropivacaine 0.75% wt/vol, 3 ml, with saline 1 ml with or without dexamethasone 4 mg) were performed on three occasions in 24 male volunteers along with an i.v. injection of saline 1 ml with or without dexamethasone 4 mg. The combinations of saline and dexamethasone were as follows: control group, perineural and i.v. saline; perineural group, perineural dexamethasone and i.v. saline; i.v. group, perineural saline and i.v. dexamethasone. Sensory block was measured using a VAS in response to pinprick testing. The duration of sensory block was the primary outcome and time to onset of sensory block the secondary outcome.ResultsAll 24 subjects completed the trial. The median [inter-quartile range (IQR)] duration of sensory block was 6.87 (5.85–7.62) h in the control group, 7.37 (5.78–7.93) h in the perineural group and 7.37 (6.10–7.97) h in the i.v. group (P=0.61). There was also no significant difference in block onset time between the three groups.ConclusionDexamethasone 4 mg has no clinically relevant effect on the duration of sensory block provided by ropivacaine applied to the ulnar nerve.Clinical trial registrationDRKS, 00014604; EudraCT, 2018-001221-98." @default.
- W2911520912 created "2019-02-21" @default.
- W2911520912 creator A5001521016 @default.
- W2911520912 creator A5017421030 @default.
- W2911520912 creator A5021497055 @default.
- W2911520912 creator A5026601827 @default.
- W2911520912 creator A5042620178 @default.
- W2911520912 creator A5059324448 @default.
- W2911520912 creator A5082498519 @default.
- W2911520912 date "2019-04-01" @default.
- W2911520912 modified "2023-10-18" @default.
- W2911520912 title "Dexamethasone as an adjuvant for peripheral nerve blockade: a randomised, triple-blinded crossover study in volunteers" @default.
- W2911520912 cites W1982321451 @default.
- W2911520912 cites W1986018857 @default.
- W2911520912 cites W1994521842 @default.
- W2911520912 cites W1998676641 @default.
- W2911520912 cites W2026941166 @default.
- W2911520912 cites W2036978803 @default.
- W2911520912 cites W2049171173 @default.
- W2911520912 cites W2062857894 @default.
- W2911520912 cites W2064568129 @default.
- W2911520912 cites W2073739607 @default.
- W2911520912 cites W2119425664 @default.
- W2911520912 cites W2120962827 @default.
- W2911520912 cites W2126365855 @default.
- W2911520912 cites W2139735390 @default.
- W2911520912 cites W2146671010 @default.
- W2911520912 cites W2319001592 @default.
- W2911520912 cites W2510266745 @default.
- W2911520912 cites W2544528202 @default.
- W2911520912 cites W2748520146 @default.
- W2911520912 cites W2777797640 @default.
- W2911520912 cites W2779892961 @default.
- W2911520912 cites W2780815759 @default.
- W2911520912 cites W2795776455 @default.
- W2911520912 doi "https://doi.org/10.1016/j.bja.2019.01.004" @default.
- W2911520912 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6435911" @default.
- W2911520912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30857609" @default.
- W2911520912 hasPublicationYear "2019" @default.
- W2911520912 type Work @default.
- W2911520912 sameAs 2911520912 @default.
- W2911520912 citedByCount "53" @default.
- W2911520912 countsByYear W29115209122019 @default.
- W2911520912 countsByYear W29115209122020 @default.
- W2911520912 countsByYear W29115209122021 @default.
- W2911520912 countsByYear W29115209122022 @default.
- W2911520912 countsByYear W29115209122023 @default.
- W2911520912 crossrefType "journal-article" @default.
- W2911520912 hasAuthorship W2911520912A5001521016 @default.
- W2911520912 hasAuthorship W2911520912A5017421030 @default.
- W2911520912 hasAuthorship W2911520912A5021497055 @default.
- W2911520912 hasAuthorship W2911520912A5026601827 @default.
- W2911520912 hasAuthorship W2911520912A5042620178 @default.
- W2911520912 hasAuthorship W2911520912A5059324448 @default.
- W2911520912 hasAuthorship W2911520912A5082498519 @default.
- W2911520912 hasBestOaLocation W29115209121 @default.
- W2911520912 hasConcept C126322002 @default.
- W2911520912 hasConcept C142724271 @default.
- W2911520912 hasConcept C204787440 @default.
- W2911520912 hasConcept C27081682 @default.
- W2911520912 hasConcept C2777197265 @default.
- W2911520912 hasConcept C2777397205 @default.
- W2911520912 hasConcept C2780269707 @default.
- W2911520912 hasConcept C2780401358 @default.
- W2911520912 hasConcept C42219234 @default.
- W2911520912 hasConcept C71924100 @default.
- W2911520912 hasConcept C87813604 @default.
- W2911520912 hasConceptScore W2911520912C126322002 @default.
- W2911520912 hasConceptScore W2911520912C142724271 @default.
- W2911520912 hasConceptScore W2911520912C204787440 @default.
- W2911520912 hasConceptScore W2911520912C27081682 @default.
- W2911520912 hasConceptScore W2911520912C2777197265 @default.
- W2911520912 hasConceptScore W2911520912C2777397205 @default.
- W2911520912 hasConceptScore W2911520912C2780269707 @default.
- W2911520912 hasConceptScore W2911520912C2780401358 @default.
- W2911520912 hasConceptScore W2911520912C42219234 @default.
- W2911520912 hasConceptScore W2911520912C71924100 @default.
- W2911520912 hasConceptScore W2911520912C87813604 @default.
- W2911520912 hasIssue "4" @default.
- W2911520912 hasLocation W29115209121 @default.
- W2911520912 hasLocation W29115209122 @default.
- W2911520912 hasLocation W29115209123 @default.
- W2911520912 hasLocation W29115209124 @default.
- W2911520912 hasOpenAccess W2911520912 @default.
- W2911520912 hasPrimaryLocation W29115209121 @default.
- W2911520912 hasRelatedWork W1985990188 @default.
- W2911520912 hasRelatedWork W2010112604 @default.
- W2911520912 hasRelatedWork W2112575754 @default.
- W2911520912 hasRelatedWork W2326910763 @default.
- W2911520912 hasRelatedWork W2329355530 @default.
- W2911520912 hasRelatedWork W2354859675 @default.
- W2911520912 hasRelatedWork W2360278750 @default.
- W2911520912 hasRelatedWork W2373797230 @default.
- W2911520912 hasRelatedWork W2619465620 @default.
- W2911520912 hasRelatedWork W2911520912 @default.
- W2911520912 hasVolume "122" @default.
- W2911520912 isParatext "false" @default.
- W2911520912 isRetracted "false" @default.