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- W2911577992 endingPage "117" @default.
- W2911577992 startingPage "103" @default.
- W2911577992 abstract "Anaerobes are known to constitute an important part of the airway microbiota in both healthy subjects and cystic fibrosis (CF) patients. Studies on the potential role of anaerobic bacteria in CF and thus their involvement in CF pathophysiology have reported contradictory results, and the question is still not elucidated. The aim of this study was to summarize anaerobe diversity in the airway microbiota and its potential role in CF, to provide an overview of the state of knowledge on anaerobe antibiotic resistances (resistome), and to investigate the detectable metabolites produced by anaerobes in CF airways (metabolome). This review emphasizes key metabolites produced by strict anaerobic bacteria (sphingolipids, fermentation-induced metabolites and metabolites involved in quorum-sensing), which may be essential for the better understanding of lung disease pathophysiology in CF." @default.
- W2911577992 created "2019-02-21" @default.
- W2911577992 creator A5002352270 @default.
- W2911577992 creator A5019796034 @default.
- W2911577992 creator A5029257143 @default.
- W2911577992 creator A5063650149 @default.
- W2911577992 creator A5074134713 @default.
- W2911577992 date "2019-01-02" @default.
- W2911577992 modified "2023-10-14" @default.
- W2911577992 title "Anaerobes in cystic fibrosis patients’ airways" @default.
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