Matches in SemOpenAlex for { <https://semopenalex.org/work/W2911683003> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2911683003 endingPage "499" @default.
- W2911683003 startingPage "494" @default.
- W2911683003 abstract "High level of HIV prevalence was found in some specific areas or populations in China. Shijingshan district was one of the areas with rapid increase of newly reported HIV cases in Beijing, China. Comprehensive investigation on HIV genetic characteristics is necessary in the district. In this study, we enrolled 223 newly identified HIV-1 sero-positive drug-naive patients from Shijingshan district. The full-length gag, pol, and partial env gene sequences were amplified and sequenced. Genetic characterization and transmission of drug resistance of HIV-1 were further investigated. Many stains, including CRF01_AE (48.25%), CRF07_BC (31.47%), subtype B (4.9%), 55_01B (1.40%), 59_01B (0.70%), 65_cpx (2.10%), 79_0107 (0.70%), and A (0.70%) and unique recombinant forms (URF) of 0107 (6.29%), 01B (1.40%), and 01BC (2.10%), were identified. Among 106 strains that harbor full-length PR gene, 10 (9.43%) strains contain mutations associated with drug resistance to protease inhibitors. Among 59 strains that harbor full-length reverse transcriptase (RT) gene, no strains contained mutations conferred to nucleoside reverse transcriptase inhibitors resistance and 4 strains (6.78%) contained drug-resistant mutations to non-nucleoside reverse transcriptase inhibitors. Among 58 sequences harboring full-length IN gene, 1 stain (1.72%) contained a mutation causing drug resistance to integrase strand transfer inhibitors. Our results provided detailed genetic data on HIV prevalent in Shijingshan district of Beijing, which would be helpful for understanding HIV-1 transmission among local populations." @default.
- W2911683003 created "2019-02-21" @default.
- W2911683003 creator A5016060445 @default.
- W2911683003 creator A5025900225 @default.
- W2911683003 creator A5035180143 @default.
- W2911683003 creator A5058965019 @default.
- W2911683003 creator A5065853735 @default.
- W2911683003 creator A5088281543 @default.
- W2911683003 creator A5089917527 @default.
- W2911683003 date "2019-05-01" @default.
- W2911683003 modified "2023-10-03" @default.
- W2911683003 title "Multiple HIV-1 Subtypes Were Found Circulating in Shijingshan District of Beijing, China" @default.
- W2911683003 cites W1990119141 @default.
- W2911683003 cites W1995762836 @default.
- W2911683003 cites W2015919512 @default.
- W2911683003 cites W2056267734 @default.
- W2911683003 cites W2109046728 @default.
- W2911683003 cites W2128260028 @default.
- W2911683003 cites W2128716276 @default.
- W2911683003 cites W2152207030 @default.
- W2911683003 cites W2154237109 @default.
- W2911683003 cites W2157702265 @default.
- W2911683003 cites W2178301797 @default.
- W2911683003 doi "https://doi.org/10.1089/aid.2018.0263" @default.
- W2911683003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30681000" @default.
- W2911683003 hasPublicationYear "2019" @default.
- W2911683003 type Work @default.
- W2911683003 sameAs 2911683003 @default.
- W2911683003 citedByCount "10" @default.
- W2911683003 countsByYear W29116830032019 @default.
- W2911683003 countsByYear W29116830032020 @default.
- W2911683003 countsByYear W29116830032021 @default.
- W2911683003 countsByYear W29116830032022 @default.
- W2911683003 countsByYear W29116830032023 @default.
- W2911683003 crossrefType "journal-article" @default.
- W2911683003 hasAuthorship W2911683003A5016060445 @default.
- W2911683003 hasAuthorship W2911683003A5025900225 @default.
- W2911683003 hasAuthorship W2911683003A5035180143 @default.
- W2911683003 hasAuthorship W2911683003A5058965019 @default.
- W2911683003 hasAuthorship W2911683003A5065853735 @default.
- W2911683003 hasAuthorship W2911683003A5088281543 @default.
- W2911683003 hasAuthorship W2911683003A5089917527 @default.
- W2911683003 hasConcept C104317684 @default.
- W2911683003 hasConcept C114851261 @default.
- W2911683003 hasConcept C119599485 @default.
- W2911683003 hasConcept C127413603 @default.
- W2911683003 hasConcept C135763542 @default.
- W2911683003 hasConcept C14430832 @default.
- W2911683003 hasConcept C156719811 @default.
- W2911683003 hasConcept C159047783 @default.
- W2911683003 hasConcept C3013748606 @default.
- W2911683003 hasConcept C49105822 @default.
- W2911683003 hasConcept C54355233 @default.
- W2911683003 hasConcept C761482 @default.
- W2911683003 hasConcept C86803240 @default.
- W2911683003 hasConceptScore W2911683003C104317684 @default.
- W2911683003 hasConceptScore W2911683003C114851261 @default.
- W2911683003 hasConceptScore W2911683003C119599485 @default.
- W2911683003 hasConceptScore W2911683003C127413603 @default.
- W2911683003 hasConceptScore W2911683003C135763542 @default.
- W2911683003 hasConceptScore W2911683003C14430832 @default.
- W2911683003 hasConceptScore W2911683003C156719811 @default.
- W2911683003 hasConceptScore W2911683003C159047783 @default.
- W2911683003 hasConceptScore W2911683003C3013748606 @default.
- W2911683003 hasConceptScore W2911683003C49105822 @default.
- W2911683003 hasConceptScore W2911683003C54355233 @default.
- W2911683003 hasConceptScore W2911683003C761482 @default.
- W2911683003 hasConceptScore W2911683003C86803240 @default.
- W2911683003 hasIssue "5" @default.
- W2911683003 hasLocation W29116830031 @default.
- W2911683003 hasLocation W29116830032 @default.
- W2911683003 hasOpenAccess W2911683003 @default.
- W2911683003 hasPrimaryLocation W29116830031 @default.
- W2911683003 hasRelatedWork W100888133 @default.
- W2911683003 hasRelatedWork W1965600002 @default.
- W2911683003 hasRelatedWork W2001977485 @default.
- W2911683003 hasRelatedWork W2049655029 @default.
- W2911683003 hasRelatedWork W2160329522 @default.
- W2911683003 hasRelatedWork W2339070198 @default.
- W2911683003 hasRelatedWork W2409806001 @default.
- W2911683003 hasRelatedWork W2563128317 @default.
- W2911683003 hasRelatedWork W3171431710 @default.
- W2911683003 hasRelatedWork W4244557550 @default.
- W2911683003 hasVolume "35" @default.
- W2911683003 isParatext "false" @default.
- W2911683003 isRetracted "false" @default.
- W2911683003 magId "2911683003" @default.
- W2911683003 workType "article" @default.