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• W2911752732 endingPage "e000310" @default.
• W2911752732 startingPage "e000310" @default.
• W2911752732 abstract "SLE poses formidable therapeutic challenges due to its heterogeneity and treatment decisions often cannot be guided by data of high quality. In this review, we attempt to provide insights regarding the treatment of SLE in everyday clinical practice, based on contemporary evidence and our own personal experience. We focus on common therapeutic issues and dilemmas arising in routine care, including monitoring for retinal toxicity associated with hydroxychloroquine, handling of glucocorticoid regimens in order to minimise their adverse events, choice of immunosuppressive medications based on prevailing disease manifestations and optimal use of available biological agents (belimumab and rituximab). We also provide our view on the position of calcineurin inhibitors in the management of lupus nephritis and conclude with remarks on the future perspectives for this challenging disease." @default.
• W2911752732 created "2019-02-21" @default.
• W2911752732 creator A5034748610 @default.
• W2911752732 creator A5059609848 @default.
• W2911752732 date "2019-02-01" @default.
• W2911752732 modified "2023-10-18" @default.
• W2911752732 title "Changing paradigms in the treatment of systemic lupus erythematosus" @default.
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• W2911752732 doi "https://doi.org/10.1136/lupus-2018-000310" @default.

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