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- W2911757039 abstract "Commentary on : Deakin B, Suckling J, Barnes TRE, et al . The benefit of minocycline on negative symptoms of schizophrenia in patients with recent-onset psychosis (BeneMin): a randomised, double-blind, placebo-controlled trial. Lancet Psychiatry 2018;5:885–94.Minocycline has been proposed as treatment for negative symptoms in schizophrenia due to its neuroprotective and anti-inflammatory properties. In two recent meta-analyses1 2 of randomised controlled trials (RCTs), minocycline outperformed placebo regarding total, general and negative symptoms. However, negative results of a large RCT (BeneMin)3 have been recently published.Population : Patients with first-episode schizophreniform disorder, schizoaffective disorder or schizophrenia within 5 years of illness onset, mild to moderate severity and positive symptoms (Positive and Negative Symptoms Scale …" @default.
- W2911757039 created "2019-02-21" @default.
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- W2911757039 date "2019-01-21" @default.
- W2911757039 modified "2023-09-24" @default.
- W2911757039 title "Adjunctive minocycline in schizophrenia: what one well-conducted study can tell us (and what it can’t)" @default.
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- W2911757039 doi "https://doi.org/10.1136/ebmental-2018-300070" @default.
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