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• W2911794275 abstract "Circulating CD8+ T cells and monocytes are activated during human immunodeficiency virus (HIV) infection and colocalize in the aortas of simian immunodeficiency virus–infected nonhuman primates. We hypothesized that CD8+ T cells could exert a proatherosclerotic effect via paracrine actions on monocytes. We found that T-cell receptor–stimulated CD8+ T cells induce monocytes to express tissue factor, a potent activator of coagulation. Tumor necrosis factor was both necessary and sufficient for this effect." @default.
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• W2911794275 date "2019-01-29" @default.
• W2911794275 modified "2023-10-15" @default.
• W2911794275 title "CD8+ T-Cell–Derived Tumor Necrosis Factor Can Induce Tissue Factor Expression on Monocytes" @default.
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• W2911794275 doi "https://doi.org/10.1093/infdis/jiz051" @default.
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