FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2911888901> ?p ?o ?g. }

• W2911888901 abstract "INTRODUCTION: Otomycosis refers to superficial, fungal infection of the external auditory canal. Aspergillus and Candida are the most common organisms causing otomycosis. AIMS AND OBJECTIVES: 1. To isolate, identify, speciate and characterise fungi isolated from patients with clinically suspected otomycosis. 2. To determine antifungal susceptibility pattern of the isolates. MATERIALS AND METHODS:This study was conducted in the Department of Microbiology, Kilpauk Medical College and Hospital, Chennai from January 2016 to December 2016. The fungi isolated from otomycosis were identified using standard identification methods. Virulence factors were determined by virulence tests. Aflatoxin production was tested by HPLC. Antifungal susceptibility was tested by microbroth dilution method for moulds and disc diffusion method for yeasts. Results were interpreted according to CLSI guidelines (M38-A2 & M44A). Rare isolates were subjected to PCR followed by Sanger sequencing. RESULT:In our study, majority of positive samples were in the age group 21-30 years (25.71%). Habitual cleaning of ear (70%) was the commonest predisposing factor. We isolated a total of 105 fungal isolates from 200 cases of clinically suspected otomycosis, among which Aspergillus niger 51 (49%) and Candida albicans 20 (19%) were the predominant species isolated. Rare isolates were Cladosporium cladosporoides (2), Aspergillus nidulans (1), Aureobasidium pullulans (1), Fonsaceae pedrosoi (1), Rhizomucor (1), Candida parapsilosis (2), Candida glabrata (1) and Candida krusei (1). Virulence factors like Biofilm in Candida species (29%), Urease and Hemolysin in Aspergillus species were produced. Higher production of Aflatoxins B1, G1 was seen with Aspergillus niger while Aspergillus flavus and Aspergillus terreus produced more amounts of Aflatoxins B2, G2. All the filamentous fungi were susceptible to antifungal drugs. Among Candida isolates, 2 Candida albicans and 1 Candida parapsilosis were resistant to Fluconazole and 1 Candida albicans was resistant to Itraconazole. 2 isolates were identified as Cladosporidium cladosporoides by PCR and Sanger sequencing. All the patients showed good response to treatment, with negative culture by 2 weeks. CONCLUSION: The present study shows that Otomycosis is a benign condition, frequently encountered in our region, which responds well to topical antifungals. Diagnosis of otomycosis at the earliest, confirmation with virulence tests and identification of antifungal susceptibility pattern is mandatory to effectively manage otomycosis without complications or recurrence." @default.
• W2911888901 created "2019-02-21" @default.
• W2911888901 creator A5043561059 @default.
• W2911888901 date "2018-05-01" @default.
• W2911888901 modified "2023-09-23" @default.
• W2911888901 title "Isolation, characterisation and antifungal sensitivity pattern of fungi causing otomycosis in patients reporting in a tertiary care hospital" @default.
• W2911888901 cites W1517444825 @default.
• W2911888901 cites W164194847 @default.
• W2911888901 cites W1969061991 @default.
• W2911888901 cites W1976824742 @default.
• W2911888901 cites W2019454044 @default.
• W2911888901 cites W2035530785 @default.
• W2911888901 cites W2042454905 @default.
• W2911888901 cites W2071426657 @default.
• W2911888901 cites W2094576454 @default.
• W2911888901 cites W2097315699 @default.
• W2911888901 cites W2098654234 @default.
• W2911888901 cites W2100958233 @default.
• W2911888901 cites W2106923956 @default.
• W2911888901 cites W2110147016 @default.
• W2911888901 cites W2113498073 @default.
• W2911888901 cites W2129339660 @default.
• W2911888901 cites W2133798991 @default.
• W2911888901 cites W2143919231 @default.
• W2911888901 cites W2144684527 @default.
• W2911888901 cites W2157592561 @default.
• W2911888901 cites W2167177000 @default.
• W2911888901 cites W2171819517 @default.
• W2911888901 cites W2335756314 @default.
• W2911888901 cites W2560089894 @default.
• W2911888901 cites W2602400328 @default.
• W2911888901 cites W2650886130 @default.
• W2911888901 hasPublicationYear "2018" @default.
• W2911888901 type Work @default.
• W2911888901 sameAs 2911888901 @default.
• W2911888901 citedByCount "0" @default.
• W2911888901 crossrefType "dissertation" @default.
• W2911888901 hasAuthorship W2911888901A5043561059 @default.
• W2911888901 hasConcept C145081991 @default.
• W2911888901 hasConcept C2777292910 @default.
• W2911888901 hasConcept C2779175654 @default.
• W2911888901 hasConcept C2779443200 @default.
• W2911888901 hasConcept C2779548794 @default.
• W2911888901 hasConcept C2779629538 @default.
• W2911888901 hasConcept C2779787849 @default.
• W2911888901 hasConcept C2780402444 @default.
• W2911888901 hasConcept C2780670043 @default.
• W2911888901 hasConcept C2780917455 @default.
• W2911888901 hasConcept C2781425774 @default.
• W2911888901 hasConcept C71924100 @default.
• W2911888901 hasConcept C86803240 @default.
• W2911888901 hasConcept C89423630 @default.
• W2911888901 hasConceptScore W2911888901C145081991 @default.
• W2911888901 hasConceptScore W2911888901C2777292910 @default.
• W2911888901 hasConceptScore W2911888901C2779175654 @default.
• W2911888901 hasConceptScore W2911888901C2779443200 @default.
• W2911888901 hasConceptScore W2911888901C2779548794 @default.
• W2911888901 hasConceptScore W2911888901C2779629538 @default.
• W2911888901 hasConceptScore W2911888901C2779787849 @default.
• W2911888901 hasConceptScore W2911888901C2780402444 @default.
• W2911888901 hasConceptScore W2911888901C2780670043 @default.
• W2911888901 hasConceptScore W2911888901C2780917455 @default.
• W2911888901 hasConceptScore W2911888901C2781425774 @default.
• W2911888901 hasConceptScore W2911888901C71924100 @default.
• W2911888901 hasConceptScore W2911888901C86803240 @default.
• W2911888901 hasConceptScore W2911888901C89423630 @default.
• W2911888901 hasLocation W29118889011 @default.
• W2911888901 hasOpenAccess W2911888901 @default.
• W2911888901 hasPrimaryLocation W29118889011 @default.
• W2911888901 hasRelatedWork W1969061991 @default.
• W2911888901 hasRelatedWork W2044576503 @default.
• W2911888901 hasRelatedWork W2049831198 @default.
• W2911888901 hasRelatedWork W2073026728 @default.
• W2911888901 hasRelatedWork W2160882181 @default.
• W2911888901 hasRelatedWork W2184746956 @default.
• W2911888901 hasRelatedWork W2437080612 @default.
• W2911888901 hasRelatedWork W2796622705 @default.
• W2911888901 hasRelatedWork W2805492197 @default.
• W2911888901 hasRelatedWork W2811160717 @default.
• W2911888901 hasRelatedWork W2889299532 @default.
• W2911888901 hasRelatedWork W2917980327 @default.
• W2911888901 hasRelatedWork W3019418164 @default.
• W2911888901 hasRelatedWork W3030806641 @default.
• W2911888901 hasRelatedWork W3137394707 @default.
• W2911888901 hasRelatedWork W3178494968 @default.
• W2911888901 hasRelatedWork W3197622013 @default.
• W2911888901 hasRelatedWork W3198066227 @default.
• W2911888901 hasRelatedWork W72623492 @default.
• W2911888901 hasRelatedWork W2946298799 @default.
• W2911888901 isParatext "false" @default.
• W2911888901 isRetracted "false" @default.
• W2911888901 magId "2911888901" @default.
• W2911888901 workType "dissertation" @default.