FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2911920471> ?p ?o ?g. }

• W2911920471 endingPage "e0211830" @default.
• W2911920471 startingPage "e0211830" @default.
• W2911920471 abstract "Purpose To investigate the role of the apparent diffusion coefficient (ADC) as a potential imaging biomarker to predict metastasis (lymph node metastasis and distant metastasis) in colon cancer based on the ADC-value of the primary tumor. Methods Thirty patients (21M, 9F) were included retrospectively. All patients received a 1.5T MRI of the colon including T2 and DWI sequences. ADC maps were calculated for each patient. An expert reader manually delineated all colon tumors to measure mean ADC and histogram metrics (mean, min, max, median, standard deviation (SD), skewness, kurtosis, 5th-95th percentiles) were calculated. Advanced colon cancer was defined as lymph node mestastasis (N+) or distant metastasis (M+). The student Mann Whitney U-test was used to assess the differences between the ADC means of early and advanced colon cancer. To compare the accuracy of lymph node metastasis (N+) prediction based on morpholigical criteria versus ADC-value of the primary tumor, two blinded readers, determined the lymph node metastasis (N0 vs N+) based on morphological criteria. The sensitivity and specificity in predicting lymph node metastasis was calculated for both readers and for the ADC-value of the primary tumor, with histopathology results as the gold standard. Results There was a significant difference between the mean ADC-value of advanced versus early tumors (p = 0.002). The optimal cut off value was 1179 * 10−3 mm2/s with an area under the curve (AUC) of 0.83 and a sensitivity and specificity of 81% and 86% respectively to predict advanced tumors. Histogram analyses did not add any significant additional value. The sensitivity and specificity for the prediction of lymph node metastasis based on morphological criteria were 40% and 63% for reader 1 and 30% and 88% for reader 2 respectively. The primary tumor ADC-value using 1.179 * 10−3 mm2/s as threshold had a 100% sensitivity and specificity in predicting lymph node metastasis. Conclusion The ADC-value of the primary tumor has the potential to predict advanced colon cancer, defined as lymph node metastasis or distant metastasis, with lower ADC values significantly associated with advanced tumors. Furthermore the ADC-value of the primary tumor increases the prediction accuracy of lymph node metastasis compared with morphological criteria." @default.
• W2911920471 created "2019-02-21" @default.
• W2911920471 creator A5005226197 @default.
• W2911920471 creator A5011147402 @default.
• W2911920471 creator A5028105973 @default.
• W2911920471 creator A5038040517 @default.
• W2911920471 creator A5040025434 @default.
• W2911920471 creator A5051180343 @default.
• W2911920471 creator A5076666925 @default.
• W2911920471 creator A5083793966 @default.
• W2911920471 creator A5085740912 @default.
• W2911920471 date "2019-02-05" @default.
• W2911920471 modified "2023-10-09" @default.
• W2911920471 title "The Apparent Diffusion Coefficient (ADC) is a useful biomarker in predicting metastatic colon cancer using the ADC-value of the primary tumor" @default.
• W2911920471 cites W1755501435 @default.
• W2911920471 cites W1871293012 @default.
• W2911920471 cites W1972366663 @default.
• W2911920471 cites W1976188153 @default.
• W2911920471 cites W2061144889 @default.
• W2911920471 cites W2068011948 @default.
• W2911920471 cites W2095658856 @default.
• W2911920471 cites W2103434973 @default.
• W2911920471 cites W2103547637 @default.
• W2911920471 cites W2113706727 @default.
• W2911920471 cites W2125452425 @default.
• W2911920471 cites W2125832740 @default.
• W2911920471 cites W2134333066 @default.
• W2911920471 cites W2136529744 @default.
• W2911920471 cites W2163522009 @default.
• W2911920471 cites W2169739251 @default.
• W2911920471 cites W2200600587 @default.
• W2911920471 cites W2275881867 @default.
• W2911920471 cites W2296350240 @default.
• W2911920471 cites W2317107657 @default.
• W2911920471 cites W2334149546 @default.
• W2911920471 cites W2336137501 @default.
• W2911920471 cites W2397055391 @default.
• W2911920471 cites W2419156502 @default.
• W2911920471 cites W2472680987 @default.
• W2911920471 cites W2505849029 @default.
• W2911920471 cites W2525758547 @default.
• W2911920471 cites W2584430967 @default.
• W2911920471 cites W2593145645 @default.
• W2911920471 cites W2598959727 @default.
• W2911920471 doi "https://doi.org/10.1371/journal.pone.0211830" @default.
• W2911920471 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6363286" @default.
• W2911920471 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30721268" @default.
• W2911920471 hasPublicationYear "2019" @default.
• W2911920471 type Work @default.
• W2911920471 sameAs 2911920471 @default.
• W2911920471 citedByCount "26" @default.
• W2911920471 countsByYear W29119204712019 @default.
• W2911920471 countsByYear W29119204712020 @default.
• W2911920471 countsByYear W29119204712021 @default.
• W2911920471 countsByYear W29119204712022 @default.
• W2911920471 countsByYear W29119204712023 @default.
• W2911920471 crossrefType "journal-article" @default.
• W2911920471 hasAuthorship W2911920471A5005226197 @default.
• W2911920471 hasAuthorship W2911920471A5011147402 @default.
• W2911920471 hasAuthorship W2911920471A5028105973 @default.
• W2911920471 hasAuthorship W2911920471A5038040517 @default.
• W2911920471 hasAuthorship W2911920471A5040025434 @default.
• W2911920471 hasAuthorship W2911920471A5051180343 @default.
• W2911920471 hasAuthorship W2911920471A5076666925 @default.
• W2911920471 hasAuthorship W2911920471A5083793966 @default.
• W2911920471 hasAuthorship W2911920471A5085740912 @default.
• W2911920471 hasBestOaLocation W29119204711 @default.
• W2911920471 hasConcept C105795698 @default.
• W2911920471 hasConcept C121608353 @default.
• W2911920471 hasConcept C126322002 @default.
• W2911920471 hasConcept C126838900 @default.
• W2911920471 hasConcept C142724271 @default.
• W2911920471 hasConcept C143409427 @default.
• W2911920471 hasConcept C143998085 @default.
• W2911920471 hasConcept C149550507 @default.
• W2911920471 hasConcept C166963901 @default.
• W2911920471 hasConcept C2779013556 @default.
• W2911920471 hasConcept C2780283643 @default.
• W2911920471 hasConcept C2780849966 @default.
• W2911920471 hasConcept C2989005 @default.
• W2911920471 hasConcept C33923547 @default.
• W2911920471 hasConcept C526805850 @default.
• W2911920471 hasConcept C70816921 @default.
• W2911920471 hasConcept C71924100 @default.
• W2911920471 hasConceptScore W2911920471C105795698 @default.
• W2911920471 hasConceptScore W2911920471C121608353 @default.
• W2911920471 hasConceptScore W2911920471C126322002 @default.
• W2911920471 hasConceptScore W2911920471C126838900 @default.
• W2911920471 hasConceptScore W2911920471C142724271 @default.
• W2911920471 hasConceptScore W2911920471C143409427 @default.
• W2911920471 hasConceptScore W2911920471C143998085 @default.
• W2911920471 hasConceptScore W2911920471C149550507 @default.
• W2911920471 hasConceptScore W2911920471C166963901 @default.
• W2911920471 hasConceptScore W2911920471C2779013556 @default.
• W2911920471 hasConceptScore W2911920471C2780283643 @default.
• W2911920471 hasConceptScore W2911920471C2780849966 @default.
• W2911920471 hasConceptScore W2911920471C2989005 @default.
• W2911920471 hasConceptScore W2911920471C33923547 @default.

• next