SemOpenAlex |

SemOpenAlex

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2911956563> ?p ?o ?g. }

Showing items 1 to 100 of ±141 with 100 items per page.

W2911956563 endingPage "203" @default.
W2911956563 startingPage "196" @default.
W2911956563 abstract "Deuteration of phospholipids is a common practice to elucidate membrane structure, dynamics and function, by providing selective visualisation in neutron scattering, nuclear magnetic resonance and vibrational spectroscopy. It is generally assumed that the properties of the deuterated lipids are identical to those of the protiated lipids, and while a number of papers have compared the properties of different forms, to date this has been no systematic study of the effects over a range of conditions. Here we present a study of the effects of deuteration on the organisation and phase behaviour of four common phospholipids (DSPC, DPPC, DMPC, DOPC), observing the effect of chain deuteration and headgroup deuteration on lipid structure and phase behaviour. For saturated lipids in excess water the gel-fluid phase transition temperature is 4.3 ± 0.1 °C lower for lipids with deuterated chains compared to protiated chains, consistent with previous work. Despite this significant change, well away from the transition structural changes as measured by powder small angle X-ray scattering are small and within errors. To investigate this further, measurements were carried out on oriented multilamellar stacks of DOPC in the fluid phase at reduced hydration. Neutrons are used in conjunction with contrast variation to elucidate the role of the deuteration explicitly. It is found that deuterated chains cause a reduction in the lamellar repeat spacing and bilayer thickness, but deuterated headgroups cause an increase. Consequences for the interpretation of Neutron Scattering data with deuterated lipids are discussed." @default.
W2911956563 created "2019-02-21" @default.
W2911956563 creator A5005042099 @default.
W2911956563 creator A5020437577 @default.
W2911956563 creator A5034186343 @default.
W2911956563 creator A5038505644 @default.
W2911956563 creator A5069486109 @default.
W2911956563 creator A5091612090 @default.
W2911956563 date "2019-05-01" @default.
W2911956563 modified "2023-10-15" @default.
W2911956563 title "Effect of deuteration on the phase behaviour and structure of lamellar phases of phosphatidylcholines – Deuterated lipids as proxies for the physical properties of native bilayers" @default.
W2911956563 cites W1527202230 @default.
W2911956563 cites W1570727417 @default.
W2911956563 cites W1607849218 @default.
W2911956563 cites W1973823143 @default.
W2911956563 cites W1977891413 @default.
W2911956563 cites W1989043041 @default.
W2911956563 cites W2001259273 @default.
W2911956563 cites W2003702862 @default.
W2911956563 cites W2006177920 @default.
W2911956563 cites W2007393373 @default.
W2911956563 cites W2008982039 @default.
W2911956563 cites W2014126179 @default.
W2911956563 cites W2014580323 @default.
W2911956563 cites W2018034970 @default.
W2911956563 cites W2018754954 @default.
W2911956563 cites W2024434342 @default.
W2911956563 cites W2028505648 @default.
W2911956563 cites W2044618471 @default.
W2911956563 cites W2046563556 @default.
W2911956563 cites W2051365309 @default.
W2911956563 cites W2055134616 @default.
W2911956563 cites W2055264015 @default.
W2911956563 cites W2062648453 @default.
W2911956563 cites W2062997019 @default.
W2911956563 cites W2074129756 @default.
W2911956563 cites W2074908042 @default.
W2911956563 cites W2078020418 @default.
W2911956563 cites W2085979983 @default.
W2911956563 cites W2085996101 @default.
W2911956563 cites W2086927005 @default.
W2911956563 cites W2088862497 @default.
W2911956563 cites W2089587226 @default.
W2911956563 cites W2101266083 @default.
W2911956563 cites W2106260465 @default.
W2911956563 cites W2113158767 @default.
W2911956563 cites W2114587261 @default.
W2911956563 cites W2118118245 @default.
W2911956563 cites W2123141349 @default.
W2911956563 cites W2146876076 @default.
W2911956563 cites W2148543667 @default.
W2911956563 cites W2149628585 @default.
W2911956563 cites W2151519197 @default.
W2911956563 cites W2156835500 @default.
W2911956563 cites W2159935409 @default.
W2911956563 cites W2742174779 @default.
W2911956563 cites W2789920014 @default.
W2911956563 doi "https://doi.org/10.1016/j.colsurfb.2019.01.040" @default.
W2911956563 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30743066" @default.
W2911956563 hasPublicationYear "2019" @default.
W2911956563 type Work @default.
W2911956563 sameAs 2911956563 @default.
W2911956563 citedByCount "23" @default.
W2911956563 countsByYear W29119565632019 @default.
W2911956563 countsByYear W29119565632020 @default.
W2911956563 countsByYear W29119565632021 @default.
W2911956563 countsByYear W29119565632022 @default.
W2911956563 countsByYear W29119565632023 @default.
W2911956563 crossrefType "journal-article" @default.
W2911956563 hasAuthorship W2911956563A5005042099 @default.
W2911956563 hasAuthorship W2911956563A5020437577 @default.
W2911956563 hasAuthorship W2911956563A5034186343 @default.
W2911956563 hasAuthorship W2911956563A5038505644 @default.
W2911956563 hasAuthorship W2911956563A5069486109 @default.
W2911956563 hasAuthorship W2911956563A5091612090 @default.
W2911956563 hasBestOaLocation W29119565632 @default.
W2911956563 hasConcept C104015590 @default.
W2911956563 hasConcept C113196181 @default.
W2911956563 hasConcept C115624301 @default.
W2911956563 hasConcept C120665830 @default.
W2911956563 hasConcept C121332964 @default.
W2911956563 hasConcept C132841051 @default.
W2911956563 hasConcept C159467904 @default.
W2911956563 hasConcept C177418412 @default.
W2911956563 hasConcept C178790620 @default.
W2911956563 hasConcept C185592680 @default.
W2911956563 hasConcept C191486275 @default.
W2911956563 hasConcept C192157962 @default.
W2911956563 hasConcept C39944091 @default.
W2911956563 hasConcept C41625074 @default.
W2911956563 hasConcept C44280652 @default.
W2911956563 hasConcept C55493867 @default.
W2911956563 hasConcept C58364064 @default.
W2911956563 hasConcept C62520636 @default.
W2911956563 hasConcept C73585123 @default.
W2911956563 hasConcept C77851909 @default.
W2911956563 hasConcept C8010536 @default.
W2911956563 hasConceptScore W2911956563C104015590 @default.