Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912004756> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2912004756 endingPage "269" @default.
- W2912004756 startingPage "267" @default.
- W2912004756 abstract "Motivation: High-throughput experimental techniques have been producing more and more protein-protein interaction (PPI) data. PPI network alignment greatly benefits the understanding of evolutionary relationship among species, helps identify conserved sub-networks and provides extra information for functional annotations. Although a few methods have been developed for multiple PPI network alignment, the alignment quality is still far away from perfect and thus, new network alignment methods are needed. Result: In this paper, we present a novel method, denoted as ConvexAlign, for joint alignment of multiple PPI networks by convex optimization of a scoring function composed of sequence similarity, topological score and interaction conservation score. In contrast to existing methods that generate multiple alignments in a greedy or progressive manner, our convex method optimizes alignments globally and enforces consistency among all pairwise alignments, resulting in much better alignment quality. Tested on both synthetic and real data, our experimental results show that ConvexAlign outperforms several popular methods in producing functionally coherent alignments. ConvexAlign even has a larger advantage over the others in aligning real PPI networks. ConvexAlign also finds a few conserved complexes among 5 species which cannot be detected by the other methods." @default.
- W2912004756 created "2019-02-21" @default.
- W2912004756 creator A5003431320 @default.
- W2912004756 creator A5019398608 @default.
- W2912004756 creator A5056540212 @default.
- W2912004756 date "2016-01-01" @default.
- W2912004756 modified "2023-09-26" @default.
- W2912004756 title "Joint Alignment of Multiple Protein-Protein Interaction Networks via Convex Optimization." @default.
- W2912004756 hasPublicationYear "2016" @default.
- W2912004756 type Work @default.
- W2912004756 sameAs 2912004756 @default.
- W2912004756 citedByCount "0" @default.
- W2912004756 crossrefType "proceedings-article" @default.
- W2912004756 hasAuthorship W2912004756A5003431320 @default.
- W2912004756 hasAuthorship W2912004756A5019398608 @default.
- W2912004756 hasAuthorship W2912004756A5056540212 @default.
- W2912004756 hasConcept C103278499 @default.
- W2912004756 hasConcept C104317684 @default.
- W2912004756 hasConcept C113174947 @default.
- W2912004756 hasConcept C11413529 @default.
- W2912004756 hasConcept C115961682 @default.
- W2912004756 hasConcept C124101348 @default.
- W2912004756 hasConcept C134306372 @default.
- W2912004756 hasConcept C14036430 @default.
- W2912004756 hasConcept C154945302 @default.
- W2912004756 hasConcept C162324750 @default.
- W2912004756 hasConcept C167625842 @default.
- W2912004756 hasConcept C176217482 @default.
- W2912004756 hasConcept C184898388 @default.
- W2912004756 hasConcept C21547014 @default.
- W2912004756 hasConcept C2776436953 @default.
- W2912004756 hasConcept C33923547 @default.
- W2912004756 hasConcept C41008148 @default.
- W2912004756 hasConcept C45484198 @default.
- W2912004756 hasConcept C51823790 @default.
- W2912004756 hasConcept C55493867 @default.
- W2912004756 hasConcept C78458016 @default.
- W2912004756 hasConcept C86803240 @default.
- W2912004756 hasConcept C88031987 @default.
- W2912004756 hasConceptScore W2912004756C103278499 @default.
- W2912004756 hasConceptScore W2912004756C104317684 @default.
- W2912004756 hasConceptScore W2912004756C113174947 @default.
- W2912004756 hasConceptScore W2912004756C11413529 @default.
- W2912004756 hasConceptScore W2912004756C115961682 @default.
- W2912004756 hasConceptScore W2912004756C124101348 @default.
- W2912004756 hasConceptScore W2912004756C134306372 @default.
- W2912004756 hasConceptScore W2912004756C14036430 @default.
- W2912004756 hasConceptScore W2912004756C154945302 @default.
- W2912004756 hasConceptScore W2912004756C162324750 @default.
- W2912004756 hasConceptScore W2912004756C167625842 @default.
- W2912004756 hasConceptScore W2912004756C176217482 @default.
- W2912004756 hasConceptScore W2912004756C184898388 @default.
- W2912004756 hasConceptScore W2912004756C21547014 @default.
- W2912004756 hasConceptScore W2912004756C2776436953 @default.
- W2912004756 hasConceptScore W2912004756C33923547 @default.
- W2912004756 hasConceptScore W2912004756C41008148 @default.
- W2912004756 hasConceptScore W2912004756C45484198 @default.
- W2912004756 hasConceptScore W2912004756C51823790 @default.
- W2912004756 hasConceptScore W2912004756C55493867 @default.
- W2912004756 hasConceptScore W2912004756C78458016 @default.
- W2912004756 hasConceptScore W2912004756C86803240 @default.
- W2912004756 hasConceptScore W2912004756C88031987 @default.
- W2912004756 hasLocation W29120047561 @default.
- W2912004756 hasOpenAccess W2912004756 @default.
- W2912004756 hasPrimaryLocation W29120047561 @default.
- W2912004756 hasRelatedWork W1723198065 @default.
- W2912004756 hasRelatedWork W1866859902 @default.
- W2912004756 hasRelatedWork W2014136705 @default.
- W2912004756 hasRelatedWork W2077222448 @default.
- W2912004756 hasRelatedWork W2091678889 @default.
- W2912004756 hasRelatedWork W2134189979 @default.
- W2912004756 hasRelatedWork W2140649038 @default.
- W2912004756 hasRelatedWork W2142343225 @default.
- W2912004756 hasRelatedWork W2147436445 @default.
- W2912004756 hasRelatedWork W2167800431 @default.
- W2912004756 hasRelatedWork W2278798970 @default.
- W2912004756 hasRelatedWork W2339661601 @default.
- W2912004756 hasRelatedWork W2614977350 @default.
- W2912004756 hasRelatedWork W3004797761 @default.
- W2912004756 hasRelatedWork W3095572487 @default.
- W2912004756 hasRelatedWork W3114061096 @default.
- W2912004756 hasRelatedWork W312089040 @default.
- W2912004756 hasRelatedWork W314988462 @default.
- W2912004756 hasRelatedWork W2098987612 @default.
- W2912004756 hasRelatedWork W2474292635 @default.
- W2912004756 isParatext "false" @default.
- W2912004756 isRetracted "false" @default.
- W2912004756 magId "2912004756" @default.
- W2912004756 workType "article" @default.