FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912012071> ?p ?o ?g. }

• W2912012071 endingPage "260" @default.
• W2912012071 startingPage "245" @default.
• W2912012071 abstract "The three human plastins (L-plastin, T-plastin, and I-plastin) are important regulatory Ca2+-binding proteins that belong to the family of actin-binding proteins. Plastins are involved in the regulation of the actin cytoskeleton as well as the cross-linking of actin filaments. In addition to four calponin-homology (CH) domains, all three plastins contain two N-terminal EF-hand Ca2+-binding motifs which together are homologous to a single lobe of the well-known calcium-regulatory protein calmodulin. This part of the protein allows for the regulation of the actin bundling activity in response to elevated calcium levels. In this protocol, we describe the purification of the EF-hand headpiece domains of all three plastins, as well as SPR studies, ITC studies, and NMR interaction studies with different peptides and calcium. In combination, these three experimental techniques provide detailed insights into a novel regulatory mechanism, involving the linker region between the EF-hand domain and the first CH domain of the plastins." @default.
• W2912012071 created "2019-02-21" @default.
• W2912012071 creator A5016247086 @default.
• W2912012071 creator A5024274003 @default.
• W2912012071 creator A5042190192 @default.
• W2912012071 creator A5051610458 @default.
• W2912012071 creator A5088712184 @default.
• W2912012071 date "2019-01-01" @default.
• W2912012071 modified "2023-10-16" @default.
• W2912012071 title "Characterization of the EF-Hand Calcium-Binding Domains of Human Plastins" @default.
• W2912012071 cites W1515707174 @default.
• W2912012071 cites W1971132134 @default.
• W2912012071 cites W1972974742 @default.
• W2912012071 cites W1988037421 @default.
• W2912012071 cites W1991576181 @default.
• W2912012071 cites W1993624759 @default.
• W2912012071 cites W2006058936 @default.
• W2912012071 cites W2017022359 @default.
• W2912012071 cites W2024534928 @default.
• W2912012071 cites W2027451081 @default.
• W2912012071 cites W2032824237 @default.
• W2912012071 cites W2038634187 @default.
• W2912012071 cites W2040279898 @default.
• W2912012071 cites W2044338132 @default.
• W2912012071 cites W2057792083 @default.
• W2912012071 cites W2060473154 @default.
• W2912012071 cites W2061725422 @default.
• W2912012071 cites W2071166522 @default.
• W2912012071 cites W2072105615 @default.
• W2912012071 cites W2099358417 @default.
• W2912012071 cites W2107879846 @default.
• W2912012071 cites W2111709677 @default.
• W2912012071 cites W2112467695 @default.
• W2912012071 cites W2125211371 @default.
• W2912012071 cites W2125616931 @default.
• W2912012071 cites W2127121668 @default.
• W2912012071 cites W2136204324 @default.
• W2912012071 cites W2136732743 @default.
• W2912012071 cites W2145367033 @default.
• W2912012071 cites W2147234043 @default.
• W2912012071 cites W2149547762 @default.
• W2912012071 cites W2150318919 @default.
• W2912012071 cites W2153294442 @default.
• W2912012071 cites W2159778631 @default.
• W2912012071 cites W2160898059 @default.
• W2912012071 cites W2165400076 @default.
• W2912012071 cites W2169130629 @default.
• W2912012071 cites W2188669773 @default.
• W2912012071 cites W2290921468 @default.
• W2912012071 cites W2548903426 @default.
• W2912012071 cites W2583350721 @default.
• W2912012071 cites W2591517417 @default.
• W2912012071 cites W2699514420 @default.
• W2912012071 cites W2732605882 @default.
• W2912012071 cites W2782523148 @default.
• W2912012071 doi "https://doi.org/10.1007/978-1-4939-9030-6_16" @default.
• W2912012071 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30710278" @default.
• W2912012071 hasPublicationYear "2019" @default.
• W2912012071 type Work @default.
• W2912012071 sameAs 2912012071 @default.
• W2912012071 citedByCount "2" @default.
• W2912012071 countsByYear W29120120712021 @default.
• W2912012071 countsByYear W29120120712023 @default.
• W2912012071 crossrefType "book-chapter" @default.
• W2912012071 hasAuthorship W2912012071A5016247086 @default.
• W2912012071 hasAuthorship W2912012071A5024274003 @default.
• W2912012071 hasAuthorship W2912012071A5042190192 @default.
• W2912012071 hasAuthorship W2912012071A5051610458 @default.
• W2912012071 hasAuthorship W2912012071A5088712184 @default.
• W2912012071 hasConcept C107824862 @default.
• W2912012071 hasConcept C111919701 @default.
• W2912012071 hasConcept C122229402 @default.
• W2912012071 hasConcept C12554922 @default.
• W2912012071 hasConcept C125705527 @default.
• W2912012071 hasConcept C142669718 @default.
• W2912012071 hasConcept C1491633281 @default.
• W2912012071 hasConcept C178790620 @default.
• W2912012071 hasConcept C185592680 @default.
• W2912012071 hasConcept C25166345 @default.
• W2912012071 hasConcept C2780557392 @default.
• W2912012071 hasConcept C2781122658 @default.
• W2912012071 hasConcept C29688787 @default.
• W2912012071 hasConcept C2993400109 @default.
• W2912012071 hasConcept C41008148 @default.
• W2912012071 hasConcept C42086223 @default.
• W2912012071 hasConcept C519063684 @default.
• W2912012071 hasConcept C55493867 @default.
• W2912012071 hasConcept C86803240 @default.
• W2912012071 hasConcept C95444343 @default.
• W2912012071 hasConceptScore W2912012071C107824862 @default.
• W2912012071 hasConceptScore W2912012071C111919701 @default.
• W2912012071 hasConceptScore W2912012071C122229402 @default.
• W2912012071 hasConceptScore W2912012071C12554922 @default.
• W2912012071 hasConceptScore W2912012071C125705527 @default.
• W2912012071 hasConceptScore W2912012071C142669718 @default.
• W2912012071 hasConceptScore W2912012071C1491633281 @default.
• W2912012071 hasConceptScore W2912012071C178790620 @default.
• W2912012071 hasConceptScore W2912012071C185592680 @default.

• next