Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912016619> ?p ?o ?g. }
- W2912016619 endingPage "81" @default.
- W2912016619 startingPage "81" @default.
- W2912016619 abstract "Although more than 100 genome sequences of Pasteurella multocida are available, comprehensive and complete genome sequence analysis is limited. This study describes the analysis of complete genome sequence and pathogenomics of P. multocida strain PMTB2.1. The genome of PMTB2.1 has 2176 genes with more than 40 coding sequences associated with iron regulation and 140 virulence genes including the complete tad locus. The tad locus includes several previously uncharacterized genes such as flp2, rcpC and tadV genes. A transposable phage resembling to Mu phages was identified in P. multocida that has not been identified in any other serotype yet. The multi-locus sequence typing analysis assigned the PMTB2.1 genome sequence as type ST101, while the comparative genome analysis showed that PMTB2.1 is closely related to other P. multocida strains with the genomic distance of less than 0.13. The expression profiling of iron regulating-genes of PMTB2.1 was characterized under iron-limited environment. Results showed significant changes in the expression profiles of iron-regulating genes (p < 0.05) whereas the highest expression of fecE gene (281 fold) at 30 min suggests utilization of the outer-membrane proteins system in iron acquisition at an early stage of growth. This study showed the phylogenomic relatedness of P. multocida and improved annotation of important genes and functional characterization of iron-regulating genes of importance to the bacterial growth." @default.
- W2912016619 created "2019-02-21" @default.
- W2912016619 creator A5000108825 @default.
- W2912016619 creator A5000585618 @default.
- W2912016619 creator A5009398379 @default.
- W2912016619 creator A5014887706 @default.
- W2912016619 creator A5026968453 @default.
- W2912016619 creator A5034991127 @default.
- W2912016619 creator A5049412526 @default.
- W2912016619 creator A5077345093 @default.
- W2912016619 creator A5087755389 @default.
- W2912016619 date "2019-01-25" @default.
- W2912016619 modified "2023-10-06" @default.
- W2912016619 title "Complete Genome Sequence Analysis and Characterization of Selected Iron Regulation Genes of Pasteurella Multocida Serotype A Strain PMTB2.1" @default.
- W2912016619 cites W1541711227 @default.
- W2912016619 cites W1547678744 @default.
- W2912016619 cites W1556176260 @default.
- W2912016619 cites W1892583423 @default.
- W2912016619 cites W1965202162 @default.
- W2912016619 cites W1967779392 @default.
- W2912016619 cites W1974116356 @default.
- W2912016619 cites W1974640383 @default.
- W2912016619 cites W1977826394 @default.
- W2912016619 cites W1978164115 @default.
- W2912016619 cites W1979471280 @default.
- W2912016619 cites W1980785096 @default.
- W2912016619 cites W1992371389 @default.
- W2912016619 cites W2003144438 @default.
- W2912016619 cites W2013388292 @default.
- W2912016619 cites W2014723793 @default.
- W2912016619 cites W2019007251 @default.
- W2912016619 cites W2021071865 @default.
- W2912016619 cites W2022442996 @default.
- W2912016619 cites W2032013011 @default.
- W2912016619 cites W2041257508 @default.
- W2912016619 cites W2043165033 @default.
- W2912016619 cites W2055606375 @default.
- W2912016619 cites W2058029053 @default.
- W2912016619 cites W2059041636 @default.
- W2912016619 cites W2079490833 @default.
- W2912016619 cites W2085154179 @default.
- W2912016619 cites W2094345028 @default.
- W2912016619 cites W2097236919 @default.
- W2912016619 cites W2099837668 @default.
- W2912016619 cites W2100363512 @default.
- W2912016619 cites W2101414295 @default.
- W2912016619 cites W2106000944 @default.
- W2912016619 cites W2114117103 @default.
- W2912016619 cites W2117418675 @default.
- W2912016619 cites W2117693434 @default.
- W2912016619 cites W2119899367 @default.
- W2912016619 cites W2121237047 @default.
- W2912016619 cites W2124715997 @default.
- W2912016619 cites W2127129693 @default.
- W2912016619 cites W2131848047 @default.
- W2912016619 cites W2133467771 @default.
- W2912016619 cites W2133659171 @default.
- W2912016619 cites W2137501972 @default.
- W2912016619 cites W2138250264 @default.
- W2912016619 cites W2145819104 @default.
- W2912016619 cites W2147804039 @default.
- W2912016619 cites W2148246095 @default.
- W2912016619 cites W2150491437 @default.
- W2912016619 cites W2155122915 @default.
- W2912016619 cites W2159840876 @default.
- W2912016619 cites W2161794813 @default.
- W2912016619 cites W2166642834 @default.
- W2912016619 cites W2169613668 @default.
- W2912016619 cites W2173913502 @default.
- W2912016619 cites W2298313749 @default.
- W2912016619 cites W2342547967 @default.
- W2912016619 cites W2529899287 @default.
- W2912016619 cites W2747175821 @default.
- W2912016619 cites W2766063150 @default.
- W2912016619 cites W4213149192 @default.
- W2912016619 cites W4298206182 @default.
- W2912016619 doi "https://doi.org/10.3390/genes10020081" @default.
- W2912016619 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6409639" @default.
- W2912016619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30691021" @default.
- W2912016619 hasPublicationYear "2019" @default.
- W2912016619 type Work @default.
- W2912016619 sameAs 2912016619 @default.
- W2912016619 citedByCount "7" @default.
- W2912016619 countsByYear W29120166192020 @default.
- W2912016619 countsByYear W29120166192021 @default.
- W2912016619 countsByYear W29120166192022 @default.
- W2912016619 countsByYear W29120166192023 @default.
- W2912016619 crossrefType "journal-article" @default.
- W2912016619 hasAuthorship W2912016619A5000108825 @default.
- W2912016619 hasAuthorship W2912016619A5000585618 @default.
- W2912016619 hasAuthorship W2912016619A5009398379 @default.
- W2912016619 hasAuthorship W2912016619A5014887706 @default.
- W2912016619 hasAuthorship W2912016619A5026968453 @default.
- W2912016619 hasAuthorship W2912016619A5034991127 @default.
- W2912016619 hasAuthorship W2912016619A5049412526 @default.
- W2912016619 hasAuthorship W2912016619A5077345093 @default.
- W2912016619 hasAuthorship W2912016619A5087755389 @default.
- W2912016619 hasBestOaLocation W29120166191 @default.