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- W2912019344 abstract "Coronaviruses (CoVs) produce a wide spectrum of disease syndromes in different mammalian and avian host species. These viruses are well-recognized for their ability to change tissue tropism, to hurdle the interspecies barriers and to adapt ecological variations. It is predicted that the inherent genetic diversity of CoVs caused by accumulation of point mutations and high frequency of homologous recombination is the principal determinant of these competences. Several CoVs (e.g. Severe acute respiratory syndrome-CoV, Middle East respiratory syndrome-CoV) have been recorded to cross the interspecies barrier, inducing different disease conditions in variable animal hosts. Bovine CoV (BCoV) is a primary cause of gastroenteritis and respiratory disease in cattle calves, winter dysentery in lactating cows and shipping fever pneumonia in feedlot cattle. Although it has long been known as a restrictive cattle pathogen, CoVs that are closely related to BCoV have been recognized in dogs, humans and in other ruminant species. Biologic, antigenic and genetic analyses of the so-called 'bovine-like CoVs' proposed classification of these viruses as host-range variants rather than distinct virus species. In this review, the different bovine-like CoVs that have been identified in domesticated ruminants (water buffalo, sheep, goat, dromedary camel, llama and alpaca) and wild ruminants (deer, wild cattle, antelopes, giraffes and wild goats) are discussed in terms of epidemiology, transmission and virus characteristics. The presented data denote the importance of these viruses in the persistence of BCoV in nature, spread to new geographical zones, and continuous emergence of disease epidemics in cattle farms." @default.
- W2912019344 created "2019-02-21" @default.
- W2912019344 creator A5072103888 @default.
- W2912019344 date "2018-12-01" @default.
- W2912019344 modified "2023-10-10" @default.
- W2912019344 title "Bovine-like coronaviruses in domestic and wild ruminants" @default.
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- W2912019344 doi "https://doi.org/10.1017/s1466252318000117" @default.
- W2912019344 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7108644" @default.
- W2912019344 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30683171" @default.
- W2912019344 hasPublicationYear "2018" @default.
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