FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912032473> ?p ?o ?g. }

• W2912032473 abstract "Serum antinuclear antibodies (ANAs) are positive in some patients with chronic lymphocytic leukemia (CLL), but the prognostic value of ANAs remains unknown. The aim of this study was to evaluate the role of ANAs as a prognostic factor in CLL.This study retrospectively analyzed clinical data from 216 newly diagnosed CLL subjects with ANAs test from 2007 to 2017. Multivariate Cox regression analyses were used to screen the independent prognostic factors related to time to first treatment (TTFT), progression free survival (PFS) and overall survival (OS). Receiver operator characteristic curves and area under the curve (AUC) were utilized to assess the predictive accuracy of ANAs together with other independent factors for OS.The incidence of ANAs abnormality at diagnosis was 13.9%. ANAs positivity and TP53 disruption were independent prognostic indicators for OS. The AUC of positive ANAs together with TP53 disruption was 0.766 (95% confidence interval [CI]: 0.697-0.826), which was significantly larger than that of either TP53 disruption (AUC: 0.706, 95% CI: 0.634-0.772, P = 0.034) or positive ANAs (AUC: 0.595, 95% CI: 0.520-0.668, P < 0.001) in OS prediction. Besides, serum positive ANAs as one additional parameter to CLL-international prognostic index (IPI) obtained superior AUCs in predicting CLL OS than CLL-IPI alone.This study identified ANAs as an independent prognostic factor for CLL, and further investigations are needed to validate this finding." @default.
• W2912032473 created "2019-02-21" @default.
• W2912032473 creator A5004231732 @default.
• W2912032473 creator A5012278873 @default.
• W2912032473 creator A5018556256 @default.
• W2912032473 creator A5029391631 @default.
• W2912032473 creator A5037740266 @default.
• W2912032473 creator A5038871279 @default.
• W2912032473 creator A5040795581 @default.
• W2912032473 creator A5046396640 @default.
• W2912032473 creator A5051677854 @default.
• W2912032473 creator A5054559272 @default.
• W2912032473 creator A5061589192 @default.
• W2912032473 creator A5076153061 @default.
• W2912032473 creator A5084871841 @default.
• W2912032473 creator A5088128630 @default.
• W2912032473 date "2019-03-05" @default.
• W2912032473 modified "2023-10-05" @default.
• W2912032473 title "Presence of serum antinuclear antibodies correlating unfavorable overall survival in patients with chronic lymphocytic leukemia" @default.
• W2912032473 cites W1657211191 @default.
• W2912032473 cites W1823414859 @default.
• W2912032473 cites W1963725668 @default.
• W2912032473 cites W1968244481 @default.
• W2912032473 cites W1982150277 @default.
• W2912032473 cites W1982422695 @default.
• W2912032473 cites W1987491773 @default.
• W2912032473 cites W2015835486 @default.
• W2912032473 cites W2019655196 @default.
• W2912032473 cites W2027755592 @default.
• W2912032473 cites W2028309555 @default.
• W2912032473 cites W2029972140 @default.
• W2912032473 cites W2031121711 @default.
• W2912032473 cites W2056503389 @default.
• W2912032473 cites W2067257663 @default.
• W2912032473 cites W2076867321 @default.
• W2912032473 cites W2088930798 @default.
• W2912032473 cites W2098576476 @default.
• W2912032473 cites W2104235597 @default.
• W2912032473 cites W2105441566 @default.
• W2912032473 cites W2109137997 @default.
• W2912032473 cites W2113794594 @default.
• W2912032473 cites W2131826846 @default.
• W2912032473 cites W2132968206 @default.
• W2912032473 cites W2136272158 @default.
• W2912032473 cites W2141219785 @default.
• W2912032473 cites W2142099365 @default.
• W2912032473 cites W2144793753 @default.
• W2912032473 cites W2162794727 @default.
• W2912032473 cites W2171693708 @default.
• W2912032473 cites W2186589950 @default.
• W2912032473 cites W2204827588 @default.
• W2912032473 cites W2230837062 @default.
• W2912032473 cites W2280983302 @default.
• W2912032473 cites W2283634497 @default.
• W2912032473 cites W2289244511 @default.
• W2912032473 cites W2328176404 @default.
• W2912032473 cites W2409184228 @default.
• W2912032473 cites W2438648502 @default.
• W2912032473 cites W2519199594 @default.
• W2912032473 cites W2558509262 @default.
• W2912032473 cites W2618614217 @default.
• W2912032473 cites W2748259124 @default.
• W2912032473 cites W2755066803 @default.
• W2912032473 cites W2791299132 @default.
• W2912032473 cites W28190658 @default.
• W2912032473 cites W4230503714 @default.
• W2912032473 cites W4235474157 @default.
• W2912032473 cites W4249923282 @default.
• W2912032473 cites W794087441 @default.
• W2912032473 doi "https://doi.org/10.1097/cm9.0000000000000114" @default.
• W2912032473 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6415995" @default.
• W2912032473 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30741830" @default.
• W2912032473 hasPublicationYear "2019" @default.
• W2912032473 type Work @default.
• W2912032473 sameAs 2912032473 @default.
• W2912032473 citedByCount "2" @default.
• W2912032473 countsByYear W29120324732021 @default.
• W2912032473 countsByYear W29120324732022 @default.
• W2912032473 crossrefType "journal-article" @default.
• W2912032473 hasAuthorship W2912032473A5004231732 @default.
• W2912032473 hasAuthorship W2912032473A5012278873 @default.
• W2912032473 hasAuthorship W2912032473A5018556256 @default.
• W2912032473 hasAuthorship W2912032473A5029391631 @default.
• W2912032473 hasAuthorship W2912032473A5037740266 @default.
• W2912032473 hasAuthorship W2912032473A5038871279 @default.
• W2912032473 hasAuthorship W2912032473A5040795581 @default.
• W2912032473 hasAuthorship W2912032473A5046396640 @default.
• W2912032473 hasAuthorship W2912032473A5051677854 @default.
• W2912032473 hasAuthorship W2912032473A5054559272 @default.
• W2912032473 hasAuthorship W2912032473A5061589192 @default.
• W2912032473 hasAuthorship W2912032473A5076153061 @default.
• W2912032473 hasAuthorship W2912032473A5084871841 @default.
• W2912032473 hasAuthorship W2912032473A5088128630 @default.
• W2912032473 hasBestOaLocation W29120324731 @default.
• W2912032473 hasConcept C10515644 @default.
• W2912032473 hasConcept C120665830 @default.
• W2912032473 hasConcept C121332964 @default.
• W2912032473 hasConcept C126322002 @default.
• W2912032473 hasConcept C143998085 @default.
• W2912032473 hasConcept C149443304 @default.

• next