FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912046551> ?p ?o ?g. }

• W2912046551 endingPage "64" @default.
• W2912046551 startingPage "64" @default.
• W2912046551 abstract "Nitrosamines are well-known carcinogenic agents. Humans are exposed to nitrosamines in various ways, the most important of which is the diet. Pentoxifylline is a xanthine derivative, which is used as a drug that inhibits inflammatory factors, reduces blood viscosity, improves peripheral blood flow, and increases oxygenation of tissue. This study was designed to evaluate the effects of pentoxifylline against damage induced by nitrosamine to the kidneys of rats. In this study, 48 male rats were randomly assigned to 8 groups: control normal group and nitrosamine control treated group (40 mg/kg); pentoxifylline groups (25, 50, 100 mg/kg) and nitrosamine + pentoxifylline treated groups (25, 50, 100 mg/kg). Treatments were administered either intraperitoneally (nitrosamine) or orally (pentoxifylline) on a daily basis for 28 days. The normalized kidney weight, glomeruli characteristics, thiobarbituric acid reactive species, antioxidant capacity, kidney function indicators, and serum nitrite oxide levels were investigated. Nitrosamine administration increased kidney malondialdehyde (MDA) level, kidney weight, blood urea nitrogen (BUN), creatinine, and nitrite oxide levels and decreased significantly glomeruli number and tissue ferric reducing/antioxidant power (FRAP) level compared to the control normal group (P < 0.05). The pentoxifylline and pentoxifylline + nitrosamine treatments reduced BUN, kidney MDA level, creatinine, glomerular diameter, and nitrite oxide levels significantly at all doses and increased the glomeruli number, kidney weight, and tissue FRAP level compared to the nitrosamine control group (P < 0.05). It seems that pentoxifylline administration improved kidney injury induced by nitrosamine in rats." @default.
• W2912046551 created "2019-02-21" @default.
• W2912046551 creator A5022781084 @default.
• W2912046551 creator A5050104582 @default.
• W2912046551 creator A5061822594 @default.
• W2912046551 creator A5075804132 @default.
• W2912046551 date "2019-01-01" @default.
• W2912046551 modified "2023-10-16" @default.
• W2912046551 title "Effect of pentoxifylline on kidney damage induced by nitrosamine in male rats" @default.
• W2912046551 cites W1965959927 @default.
• W2912046551 cites W1975908245 @default.
• W2912046551 cites W2002115840 @default.
• W2912046551 cites W2005737558 @default.
• W2912046551 cites W2012826931 @default.
• W2912046551 cites W2027619293 @default.
• W2912046551 cites W2029190339 @default.
• W2912046551 cites W2050116667 @default.
• W2912046551 cites W2084751750 @default.
• W2912046551 cites W2090714091 @default.
• W2912046551 cites W2119903193 @default.
• W2912046551 cites W2136840488 @default.
• W2912046551 cites W2162589336 @default.
• W2912046551 cites W2170079722 @default.
• W2912046551 cites W2205425710 @default.
• W2912046551 cites W2314295465 @default.
• W2912046551 cites W2584770232 @default.
• W2912046551 cites W2605811181 @default.
• W2912046551 cites W2732909657 @default.
• W2912046551 cites W2745202323 @default.
• W2912046551 cites W2794090315 @default.
• W2912046551 cites W2806432643 @default.
• W2912046551 cites W2810667991 @default.
• W2912046551 cites W2891218385 @default.
• W2912046551 doi "https://doi.org/10.4103/1735-5362.251854" @default.
• W2912046551 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6407339" @default.
• W2912046551 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30936934" @default.
• W2912046551 hasPublicationYear "2019" @default.
• W2912046551 type Work @default.
• W2912046551 sameAs 2912046551 @default.
• W2912046551 citedByCount "9" @default.
• W2912046551 countsByYear W29120465512019 @default.
• W2912046551 countsByYear W29120465512020 @default.
• W2912046551 countsByYear W29120465512021 @default.
• W2912046551 countsByYear W29120465512022 @default.
• W2912046551 countsByYear W29120465512023 @default.
• W2912046551 crossrefType "journal-article" @default.
• W2912046551 hasAuthorship W2912046551A5022781084 @default.
• W2912046551 hasAuthorship W2912046551A5050104582 @default.
• W2912046551 hasAuthorship W2912046551A5061822594 @default.
• W2912046551 hasAuthorship W2912046551A5075804132 @default.
• W2912046551 hasBestOaLocation W29120465511 @default.
• W2912046551 hasConcept C114246631 @default.
• W2912046551 hasConcept C126322002 @default.
• W2912046551 hasConcept C134018914 @default.
• W2912046551 hasConcept C159641895 @default.
• W2912046551 hasConcept C178790620 @default.
• W2912046551 hasConcept C185592680 @default.
• W2912046551 hasConcept C2776179834 @default.
• W2912046551 hasConcept C2776384668 @default.
• W2912046551 hasConcept C2777395278 @default.
• W2912046551 hasConcept C2778004101 @default.
• W2912046551 hasConcept C2778401633 @default.
• W2912046551 hasConcept C2780091579 @default.
• W2912046551 hasConcept C2780306776 @default.
• W2912046551 hasConcept C2780404050 @default.
• W2912046551 hasConcept C519581460 @default.
• W2912046551 hasConcept C55493867 @default.
• W2912046551 hasConcept C71924100 @default.
• W2912046551 hasConcept C98274493 @default.
• W2912046551 hasConceptScore W2912046551C114246631 @default.
• W2912046551 hasConceptScore W2912046551C126322002 @default.
• W2912046551 hasConceptScore W2912046551C134018914 @default.
• W2912046551 hasConceptScore W2912046551C159641895 @default.
• W2912046551 hasConceptScore W2912046551C178790620 @default.
• W2912046551 hasConceptScore W2912046551C185592680 @default.
• W2912046551 hasConceptScore W2912046551C2776179834 @default.
• W2912046551 hasConceptScore W2912046551C2776384668 @default.
• W2912046551 hasConceptScore W2912046551C2777395278 @default.
• W2912046551 hasConceptScore W2912046551C2778004101 @default.
• W2912046551 hasConceptScore W2912046551C2778401633 @default.
• W2912046551 hasConceptScore W2912046551C2780091579 @default.
• W2912046551 hasConceptScore W2912046551C2780306776 @default.
• W2912046551 hasConceptScore W2912046551C2780404050 @default.
• W2912046551 hasConceptScore W2912046551C519581460 @default.
• W2912046551 hasConceptScore W2912046551C55493867 @default.
• W2912046551 hasConceptScore W2912046551C71924100 @default.
• W2912046551 hasConceptScore W2912046551C98274493 @default.
• W2912046551 hasIssue "1" @default.
• W2912046551 hasLocation W29120465511 @default.
• W2912046551 hasLocation W29120465512 @default.
• W2912046551 hasLocation W29120465513 @default.
• W2912046551 hasLocation W29120465514 @default.
• W2912046551 hasOpenAccess W2912046551 @default.
• W2912046551 hasPrimaryLocation W29120465511 @default.
• W2912046551 hasRelatedWork W1157758552 @default.
• W2912046551 hasRelatedWork W1985357575 @default.
• W2912046551 hasRelatedWork W2016065529 @default.
• W2912046551 hasRelatedWork W2040542718 @default.

• next