Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912046695> ?p ?o ?g. }
- W2912046695 endingPage "873" @default.
- W2912046695 startingPage "865" @default.
- W2912046695 abstract "The action spectrum for bilirubin photodegradation has been intensively studied. However, questions still remain regarding which light wavelength most efficiently photodegrades bilirubin. In this study, we determined the in vitro effects of different irradiation wavelength ranges on bilirubin photodegradation. In our in vitro method, normalized absolute irradiance levels of 4.2 × 1015 photons/cm2/s from light-emitting diodes (ranging from 390–530 nm) and 10-nm band-pass filters were used to irradiate bilirubin solutions (25 mg/dL in 4% human serum albumin). Bilirubin and its major photoisomer concentrations were determined; the half-life time of bilirubin (t1/2) was calculated for each wavelength range, and the spectral characteristics for bilirubin photodegradation products were obtained for key wavelengths. The in vitro photodegradation of bilirubin at 37 °C decreased linearly as the wavelength was increased from 390 to 500 nm with t1/2 decreasing from 63 to 17 min, respectively. At 460 ± 10 nm, a significantly lower rate of photodegradation and thus higher t1/2 (31 min) than that at 500 nm (17 min) was demonstrated. In our system, the optimum bilirubin photodegradation and lumirubin production rates occurred between 490 and 500 nm. Spectra shapes were remarkably similar, suggesting that lumirubin production was the major process of bilirubin photodegradation." @default.
- W2912046695 created "2019-02-21" @default.
- W2912046695 creator A5004500107 @default.
- W2912046695 creator A5004502456 @default.
- W2912046695 creator A5030732274 @default.
- W2912046695 creator A5032263600 @default.
- W2912046695 creator A5037255553 @default.
- W2912046695 creator A5046701485 @default.
- W2912046695 creator A5055733234 @default.
- W2912046695 creator A5063792544 @default.
- W2912046695 creator A5086729574 @default.
- W2912046695 creator A5088490080 @default.
- W2912046695 date "2019-01-26" @default.
- W2912046695 modified "2023-10-10" @default.
- W2912046695 title "The effect of light wavelength on in vitro bilirubin photodegradation and photoisomer production" @default.
- W2912046695 cites W1157382975 @default.
- W2912046695 cites W1684644586 @default.
- W2912046695 cites W1884687305 @default.
- W2912046695 cites W1891693160 @default.
- W2912046695 cites W1945175215 @default.
- W2912046695 cites W1975776648 @default.
- W2912046695 cites W1976451021 @default.
- W2912046695 cites W1977471496 @default.
- W2912046695 cites W1986886255 @default.
- W2912046695 cites W1990380861 @default.
- W2912046695 cites W1990692585 @default.
- W2912046695 cites W2006120847 @default.
- W2912046695 cites W2009774995 @default.
- W2912046695 cites W2014081858 @default.
- W2912046695 cites W2018651559 @default.
- W2912046695 cites W2020526511 @default.
- W2912046695 cites W2020759312 @default.
- W2912046695 cites W2031481268 @default.
- W2912046695 cites W2032501765 @default.
- W2912046695 cites W2033758553 @default.
- W2912046695 cites W2034461335 @default.
- W2912046695 cites W2041648302 @default.
- W2912046695 cites W2049494030 @default.
- W2912046695 cites W2061720867 @default.
- W2912046695 cites W2072085765 @default.
- W2912046695 cites W2072374823 @default.
- W2912046695 cites W2081878231 @default.
- W2912046695 cites W2082982868 @default.
- W2912046695 cites W2093063042 @default.
- W2912046695 cites W2094103011 @default.
- W2912046695 cites W2094891799 @default.
- W2912046695 cites W2117880641 @default.
- W2912046695 cites W2124530579 @default.
- W2912046695 cites W2126287612 @default.
- W2912046695 cites W2168132264 @default.
- W2912046695 cites W2172026633 @default.
- W2912046695 cites W2324726417 @default.
- W2912046695 cites W2462376763 @default.
- W2912046695 cites W2800168656 @default.
- W2912046695 cites W2950017959 @default.
- W2912046695 doi "https://doi.org/10.1038/s41390-019-0310-2" @default.
- W2912046695 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30710116" @default.
- W2912046695 hasPublicationYear "2019" @default.
- W2912046695 type Work @default.
- W2912046695 sameAs 2912046695 @default.
- W2912046695 citedByCount "16" @default.
- W2912046695 countsByYear W29120466952019 @default.
- W2912046695 countsByYear W29120466952020 @default.
- W2912046695 countsByYear W29120466952021 @default.
- W2912046695 countsByYear W29120466952023 @default.
- W2912046695 crossrefType "journal-article" @default.
- W2912046695 hasAuthorship W2912046695A5004500107 @default.
- W2912046695 hasAuthorship W2912046695A5004502456 @default.
- W2912046695 hasAuthorship W2912046695A5030732274 @default.
- W2912046695 hasAuthorship W2912046695A5032263600 @default.
- W2912046695 hasAuthorship W2912046695A5037255553 @default.
- W2912046695 hasAuthorship W2912046695A5046701485 @default.
- W2912046695 hasAuthorship W2912046695A5055733234 @default.
- W2912046695 hasAuthorship W2912046695A5063792544 @default.
- W2912046695 hasAuthorship W2912046695A5086729574 @default.
- W2912046695 hasAuthorship W2912046695A5088490080 @default.
- W2912046695 hasBestOaLocation W29120466951 @default.
- W2912046695 hasConcept C120665830 @default.
- W2912046695 hasConcept C121332964 @default.
- W2912046695 hasConcept C126322002 @default.
- W2912046695 hasConcept C161790260 @default.
- W2912046695 hasConcept C162847780 @default.
- W2912046695 hasConcept C185592680 @default.
- W2912046695 hasConcept C192562407 @default.
- W2912046695 hasConcept C202751555 @default.
- W2912046695 hasConcept C2777513400 @default.
- W2912046695 hasConcept C46423501 @default.
- W2912046695 hasConcept C49040817 @default.
- W2912046695 hasConcept C55493867 @default.
- W2912046695 hasConcept C6260449 @default.
- W2912046695 hasConcept C65165184 @default.
- W2912046695 hasConcept C71924100 @default.
- W2912046695 hasConcept C75473681 @default.
- W2912046695 hasConceptScore W2912046695C120665830 @default.
- W2912046695 hasConceptScore W2912046695C121332964 @default.
- W2912046695 hasConceptScore W2912046695C126322002 @default.
- W2912046695 hasConceptScore W2912046695C161790260 @default.
- W2912046695 hasConceptScore W2912046695C162847780 @default.