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- W2912053985 abstract "The term secondary osteoporosis (SO) identifies a reduction of bone mass related to a well-established disease or pharmacological agent. The identification of the underlying disease often represents a challenging situation in clinical practice.The prevalence of SO in the real world may vary, ranging from 17% to 80%; therefore, search for a form of SO represents a pillar when evaluating patients with osteoporosis. Guidelines for treatment of specific secondary forms of osteoporosis, such as glucocorticoid-induced osteoporosis, have been published even though often neglected in clinical practice. For the majority of SO, there are currently no specific guidelines concerning treatment with only few trials showing the effect of bone-active drugs on fracture risk reduction.Healthcare professionals should be aware of the secondary forms of osteoporosis, in particular when the reason for reduced skeletal resistance is uncertain or when bone mineral density results are unsatisfactory in a patient compliant to therapy. In a few cases (such as, for example: no response to therapy, better classification of bone involvement in patients with kidney failure, suspicion of rare metabolic bone disease) bone biopsy is needed to investigate the patient. This review highlights recent advances in understanding and managing SO." @default.
- W2912053985 created "2019-02-21" @default.
- W2912053985 creator A5015966662 @default.
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- W2912053985 creator A5052786698 @default.
- W2912053985 creator A5054016902 @default.
- W2912053985 creator A5078177918 @default.
- W2912053985 date "2019-02-08" @default.
- W2912053985 modified "2023-10-16" @default.
- W2912053985 title "Understanding and managing secondary osteoporosis" @default.
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