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• W2912069976 abstract "Soluble forms of the coinhibitory receptors programmed death 1 (PD-1) and Tim-3 exist, but their relationship with T-cell surface expression remains unclear. When measured by an enzyme-linked immunosorbent assay in plasma, soluble PD-1, and soluble Tim-3 were elevated during primary HIV infection, decreased on antiretroviral therapy to levels found in controls, and correlated with cell surface expression. We conclude that soluble PD-1 and soluble Tim-3 are easy to measure biomarkers of immune exhaustion which potentially eliminate the need for flow cytometry." @default.
• W2912069976 created "2019-02-21" @default.
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• W2912069976 date "2019-06-01" @default.
• W2912069976 modified "2023-10-05" @default.
• W2912069976 title "Soluble plasma programmed death 1 (PD-1) and Tim-3 in primary HIV infection" @default.
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• W2912069976 doi "https://doi.org/10.1097/qad.0000000000002165" @default.
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