FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912072547> ?p ?o ?g. }

• W2912072547 abstract "Abstract Background Sagittal craniosynostosis (SCS), the most common type of premature perinatal cranial suture fusion, results in abnormal head shape that requires extensive surgery to correct. It is important to find objective and repeatable measures of severity and surgical outcome to examine the effect of timing and technique on different SCS surgeries. The purpose of this study was to develop statistical models of infant (0-6 months old) skull growth in both normative and SCS subjects (prior to surgery). Our goal was to apply these models to the assessment of differences between these two groups in overall post-natal growth patterns and sutural growth rates as a first step to develop methods for predictive models of surgical outcome. Methods and Findings: We identified 81 patients with isolated, non-syndromic SCS from Seattle Children’s Craniofacial Center patient database who had a pre-operative CT exam before the age of six months. As a control group, we identified 117 CT exams without any craniofacial abnormalities or bone fractures in the same age group. We first created population-level templates from the CT images of the SCS and normal groups. All CT images from both groups, as well as the canonical templates of both cohorts were annotated with anatomical landmarks, which were used in a growth model that predicted the locations of these landmarks at a given age based on each population. Using the template images and the landmark positions predicted by the growth models, we created 3D meshes for each week of age up to six months for both populations. To analyze the growth patterns at the suture sites, we annotated both templates with additional semi-landmarks equally spaced along the metopic, coronal, sagittal and lambdoidal cranial sutures. By transferring these semi-landmarks to meshes produced from the growth model, we measured the displacement of the bone borders and suture closure rates. We found that the growth at the metopic and coronal sutures were more rapid in the SCS cohort compared to the normal cohort. The antero-posterior displacement of the semi-landmarks indicated a more rapid growth in the sagittal plane in the SCS model compared to the normal model as well. Conclusions: Statistical templates and geometric morphometrics are promising tools for understanding the growth patterns in normal and synostotic populations and to produce objective and reproducible measurements of severity and outcome. Our study is the first of its kind to quantify the bone growth for the first six months of life in both normal and sagittal synostosis patients." @default.
• W2912072547 created "2019-02-21" @default.
• W2912072547 creator A5010427214 @default.
• W2912072547 creator A5014812866 @default.
• W2912072547 creator A5041416198 @default.
• W2912072547 date "2019-01-24" @default.
• W2912072547 modified "2023-09-27" @default.
• W2912072547 title "Cranial Bone Growth in Isolated Sagittal Craniosynostosis Compared to Normal Growth in the First Six Months of Age" @default.
• W2912072547 cites W1571578421 @default.
• W2912072547 cites W1909390124 @default.
• W2912072547 cites W1971019753 @default.
• W2912072547 cites W1978720148 @default.
• W2912072547 cites W1983249739 @default.
• W2912072547 cites W1991739813 @default.
• W2912072547 cites W1999638379 @default.
• W2912072547 cites W2007009009 @default.
• W2912072547 cites W2026616100 @default.
• W2912072547 cites W2030157853 @default.
• W2912072547 cites W2031912524 @default.
• W2912072547 cites W2040616009 @default.
• W2912072547 cites W2040652369 @default.
• W2912072547 cites W2069709722 @default.
• W2912072547 cites W2076479775 @default.
• W2912072547 cites W2080492264 @default.
• W2912072547 cites W2084205027 @default.
• W2912072547 cites W2102892728 @default.
• W2912072547 cites W2128409098 @default.
• W2912072547 cites W2131023231 @default.
• W2912072547 cites W2136145485 @default.
• W2912072547 cites W2149632571 @default.
• W2912072547 cites W2165149719 @default.
• W2912072547 cites W2168424657 @default.
• W2912072547 cites W2205565364 @default.
• W2912072547 cites W2229412420 @default.
• W2912072547 cites W226880487 @default.
• W2912072547 cites W2281294563 @default.
• W2912072547 cites W2295566500 @default.
• W2912072547 cites W2305024637 @default.
• W2912072547 cites W2312575778 @default.
• W2912072547 cites W2342656044 @default.
• W2912072547 cites W2343298606 @default.
• W2912072547 cites W2514477743 @default.
• W2912072547 cites W2604243177 @default.
• W2912072547 cites W2618642049 @default.
• W2912072547 cites W2729984968 @default.
• W2912072547 cites W2760023819 @default.
• W2912072547 cites W2769488701 @default.
• W2912072547 cites W4235520325 @default.
• W2912072547 cites W4240670390 @default.
• W2912072547 cites W4250636285 @default.
• W2912072547 cites W921751961 @default.
• W2912072547 doi "https://doi.org/10.1101/528869" @default.
• W2912072547 hasPublicationYear "2019" @default.
• W2912072547 type Work @default.
• W2912072547 sameAs 2912072547 @default.
• W2912072547 citedByCount "0" @default.
• W2912072547 crossrefType "posted-content" @default.
• W2912072547 hasAuthorship W2912072547A5010427214 @default.
• W2912072547 hasAuthorship W2912072547A5014812866 @default.
• W2912072547 hasAuthorship W2912072547A5041416198 @default.
• W2912072547 hasBestOaLocation W29120725471 @default.
• W2912072547 hasConcept C105702510 @default.
• W2912072547 hasConcept C118552586 @default.
• W2912072547 hasConcept C126322002 @default.
• W2912072547 hasConcept C141071460 @default.
• W2912072547 hasConcept C178910020 @default.
• W2912072547 hasConcept C24543465 @default.
• W2912072547 hasConcept C2777081826 @default.
• W2912072547 hasConcept C2777327002 @default.
• W2912072547 hasConcept C2778043341 @default.
• W2912072547 hasConcept C2778607769 @default.
• W2912072547 hasConcept C2779300802 @default.
• W2912072547 hasConcept C2779302956 @default.
• W2912072547 hasConcept C2780639360 @default.
• W2912072547 hasConcept C2781245598 @default.
• W2912072547 hasConcept C2908647359 @default.
• W2912072547 hasConcept C2911059045 @default.
• W2912072547 hasConcept C29694066 @default.
• W2912072547 hasConcept C2991750140 @default.
• W2912072547 hasConcept C71924100 @default.
• W2912072547 hasConcept C99454951 @default.
• W2912072547 hasConceptScore W2912072547C105702510 @default.
• W2912072547 hasConceptScore W2912072547C118552586 @default.
• W2912072547 hasConceptScore W2912072547C126322002 @default.
• W2912072547 hasConceptScore W2912072547C141071460 @default.
• W2912072547 hasConceptScore W2912072547C178910020 @default.
• W2912072547 hasConceptScore W2912072547C24543465 @default.
• W2912072547 hasConceptScore W2912072547C2777081826 @default.
• W2912072547 hasConceptScore W2912072547C2777327002 @default.
• W2912072547 hasConceptScore W2912072547C2778043341 @default.
• W2912072547 hasConceptScore W2912072547C2778607769 @default.
• W2912072547 hasConceptScore W2912072547C2779300802 @default.
• W2912072547 hasConceptScore W2912072547C2779302956 @default.
• W2912072547 hasConceptScore W2912072547C2780639360 @default.
• W2912072547 hasConceptScore W2912072547C2781245598 @default.
• W2912072547 hasConceptScore W2912072547C2908647359 @default.
• W2912072547 hasConceptScore W2912072547C2911059045 @default.
• W2912072547 hasConceptScore W2912072547C29694066 @default.
• W2912072547 hasConceptScore W2912072547C2991750140 @default.
• W2912072547 hasConceptScore W2912072547C71924100 @default.

• next