FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912078781> ?p ?o ?g. }

• W2912078781 endingPage "695" @default.
• W2912078781 startingPage "695" @default.
• W2912078781 abstract "The fibroblast growth factor (FGF) signaling pathway plays a key role in tumorigenesis and is recognized as a potential therapeutic target. In this study, the authors aimed to assess the impact of serum FGF23 levels in the prognosis of patients with cancer and bone metastases from solid tumors. A cohort of 112 patients with cancer and metastatic bone disease were treated with bone-targeted agents (BTA). Serum baseline FGF23 was quantified by ELISA and dichotomized in FGF23high and FGF23low groups. Additionally, the association between FGF23 and overall survival (OS) and time to skeletal-related events (TTSRE) was investigated. Baseline characteristics were balanced between groups, except for the median urinary N-terminal telopeptide (uNTX) level. After a median follow-up of 26.0 months, a median OS of 34.4 and 12.2 months was found in the FGF23low and FGF23high groups, respectively (multivariate HR 0.18, 95% CI 0.07–0.44, p = 0.001; univariate HR 0.27, p = 0.001). Additionally, TTSRE was significantly longer for patients with FGF23low (13.0 vs 2.0 months, p = 0.04). Overall, this study found that patients with FGF23low at baseline had longer OS and TTSRE. Further studies are warranted to define its role as a prognostic biomarker and in the use of drugs targeting the FGF axis." @default.
• W2912078781 created "2019-02-21" @default.
• W2912078781 creator A5004418198 @default.
• W2912078781 creator A5008670363 @default.
• W2912078781 creator A5019024895 @default.
• W2912078781 creator A5038587743 @default.
• W2912078781 creator A5038667944 @default.
• W2912078781 creator A5040731722 @default.
• W2912078781 creator A5045641506 @default.
• W2912078781 creator A5051232543 @default.
• W2912078781 creator A5059795130 @default.
• W2912078781 creator A5070571247 @default.
• W2912078781 creator A5075304660 @default.
• W2912078781 creator A5076533193 @default.
• W2912078781 creator A5078184472 @default.
• W2912078781 date "2019-02-06" @default.
• W2912078781 modified "2023-10-16" @default.
• W2912078781 title "Levels of Circulating Fibroblast Growth Factor 23 (FGF23) and Prognosis in Cancer Patients with Bone Metastases" @default.
• W2912078781 cites W1527661581 @default.
• W2912078781 cites W2011349880 @default.
• W2912078781 cites W2021852822 @default.
• W2912078781 cites W2054151200 @default.
• W2912078781 cites W2063765502 @default.
• W2912078781 cites W2083288593 @default.
• W2912078781 cites W2106115383 @default.
• W2912078781 cites W2128059069 @default.
• W2912078781 cites W2144414222 @default.
• W2912078781 cites W2170351820 @default.
• W2912078781 cites W2347062064 @default.
• W2912078781 cites W2563337881 @default.
• W2912078781 cites W2581473153 @default.
• W2912078781 cites W2736265510 @default.
• W2912078781 cites W2741790413 @default.
• W2912078781 cites W2762381618 @default.
• W2912078781 doi "https://doi.org/10.3390/ijms20030695" @default.
• W2912078781 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6387099" @default.
• W2912078781 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30736285" @default.
• W2912078781 hasPublicationYear "2019" @default.
• W2912078781 type Work @default.
• W2912078781 sameAs 2912078781 @default.
• W2912078781 citedByCount "15" @default.
• W2912078781 countsByYear W29120787812019 @default.
• W2912078781 countsByYear W29120787812020 @default.
• W2912078781 countsByYear W29120787812021 @default.
• W2912078781 countsByYear W29120787812022 @default.
• W2912078781 countsByYear W29120787812023 @default.
• W2912078781 crossrefType "journal-article" @default.
• W2912078781 hasAuthorship W2912078781A5004418198 @default.
• W2912078781 hasAuthorship W2912078781A5008670363 @default.
• W2912078781 hasAuthorship W2912078781A5019024895 @default.
• W2912078781 hasAuthorship W2912078781A5038587743 @default.
• W2912078781 hasAuthorship W2912078781A5038667944 @default.
• W2912078781 hasAuthorship W2912078781A5040731722 @default.
• W2912078781 hasAuthorship W2912078781A5045641506 @default.
• W2912078781 hasAuthorship W2912078781A5051232543 @default.
• W2912078781 hasAuthorship W2912078781A5059795130 @default.
• W2912078781 hasAuthorship W2912078781A5070571247 @default.
• W2912078781 hasAuthorship W2912078781A5075304660 @default.
• W2912078781 hasAuthorship W2912078781A5076533193 @default.
• W2912078781 hasAuthorship W2912078781A5078184472 @default.
• W2912078781 hasBestOaLocation W29120787811 @default.
• W2912078781 hasConcept C114276007 @default.
• W2912078781 hasConcept C121608353 @default.
• W2912078781 hasConcept C125870589 @default.
• W2912078781 hasConcept C126322002 @default.
• W2912078781 hasConcept C131075544 @default.
• W2912078781 hasConcept C143998085 @default.
• W2912078781 hasConcept C144301174 @default.
• W2912078781 hasConcept C160160445 @default.
• W2912078781 hasConcept C181199279 @default.
• W2912078781 hasConcept C185592680 @default.
• W2912078781 hasConcept C2777783956 @default.
• W2912078781 hasConcept C2779013556 @default.
• W2912078781 hasConcept C2781197716 @default.
• W2912078781 hasConcept C2781208988 @default.
• W2912078781 hasConcept C38180746 @default.
• W2912078781 hasConcept C519063684 @default.
• W2912078781 hasConcept C55493867 @default.
• W2912078781 hasConcept C71924100 @default.
• W2912078781 hasConcept C90924648 @default.
• W2912078781 hasConceptScore W2912078781C114276007 @default.
• W2912078781 hasConceptScore W2912078781C121608353 @default.
• W2912078781 hasConceptScore W2912078781C125870589 @default.
• W2912078781 hasConceptScore W2912078781C126322002 @default.
• W2912078781 hasConceptScore W2912078781C131075544 @default.
• W2912078781 hasConceptScore W2912078781C143998085 @default.
• W2912078781 hasConceptScore W2912078781C144301174 @default.
• W2912078781 hasConceptScore W2912078781C160160445 @default.
• W2912078781 hasConceptScore W2912078781C181199279 @default.
• W2912078781 hasConceptScore W2912078781C185592680 @default.
• W2912078781 hasConceptScore W2912078781C2777783956 @default.
• W2912078781 hasConceptScore W2912078781C2779013556 @default.
• W2912078781 hasConceptScore W2912078781C2781197716 @default.
• W2912078781 hasConceptScore W2912078781C2781208988 @default.
• W2912078781 hasConceptScore W2912078781C38180746 @default.
• W2912078781 hasConceptScore W2912078781C519063684 @default.
• W2912078781 hasConceptScore W2912078781C55493867 @default.
• W2912078781 hasConceptScore W2912078781C71924100 @default.

• next