FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912082863> ?p ?o ?g. }

• W2912082863 endingPage "1" @default.
• W2912082863 startingPage "1" @default.
• W2912082863 abstract "Optical coherence tomography (OCT) is an emerging technology for in vivo airway and lung imaging. However, OCT lacks sensitivity to the metabolic changes caused by inflammation, which drives chronic respiratory diseases such as asthma and chronic obstructive pulmonary disorder. Redox imaging (RI) is a label-free technique that uses the autofluorescence of the metabolic coenzymes NAD(P)H and flavin adenine dinucleotide (FAD) to probe cellular metabolism and could provide complimentary information to OCT for airway and lung imaging. We demonstrate OCT and RI of respiratory ciliated epithelial function in ex vivo mouse tracheae. We applied RI to measure cellular metabolism via the redox ratio [intensity of NAD(P)H divided by FAD] and particle tracking velocimetry OCT to quantify cilia-driven fluid flow. To model mitochondrial dysfunction, a key aspect of the inflammatory process, cyanide was used to inhibit oxidative metabolism and reduce ciliary motility. Cyanide exposure over 20 min significantly increased the redox ratio and reversed cilia-driven fluid flow. We propose that RI provides complementary information to OCT to assess inflammation in the airway and lungs." @default.
• W2912082863 created "2019-02-21" @default.
• W2912082863 creator A5002041636 @default.
• W2912082863 creator A5029201667 @default.
• W2912082863 creator A5065781899 @default.
• W2912082863 creator A5074251094 @default.
• W2912082863 creator A5090347703 @default.
• W2912082863 date "2019-01-30" @default.
• W2912082863 modified "2023-09-25" @default.
• W2912082863 title "Redox imaging and optical coherence tomography of the respiratory ciliated epithelium" @default.
• W2912082863 cites W1973987812 @default.
• W2912082863 cites W2036956044 @default.
• W2912082863 cites W2044356754 @default.
• W2912082863 cites W2053798956 @default.
• W2912082863 cites W2072775705 @default.
• W2912082863 cites W2097683070 @default.
• W2912082863 cites W2121388227 @default.
• W2912082863 cites W2154488543 @default.
• W2912082863 cites W2158794068 @default.
• W2912082863 cites W2462810089 @default.
• W2912082863 cites W2529052661 @default.
• W2912082863 cites W2561612116 @default.
• W2912082863 cites W2593296415 @default.
• W2912082863 cites W2602958960 @default.
• W2912082863 doi "https://doi.org/10.1117/1.jbo.24.1.010501" @default.
• W2912082863 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6985682" @default.
• W2912082863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30701725" @default.
• W2912082863 hasPublicationYear "2019" @default.
• W2912082863 type Work @default.
• W2912082863 sameAs 2912082863 @default.
• W2912082863 citedByCount "2" @default.
• W2912082863 countsByYear W29120828632021 @default.
• W2912082863 countsByYear W29120828632023 @default.
• W2912082863 crossrefType "journal-article" @default.
• W2912082863 hasAuthorship W2912082863A5002041636 @default.
• W2912082863 hasAuthorship W2912082863A5029201667 @default.
• W2912082863 hasAuthorship W2912082863A5065781899 @default.
• W2912082863 hasAuthorship W2912082863A5074251094 @default.
• W2912082863 hasAuthorship W2912082863A5090347703 @default.
• W2912082863 hasBestOaLocation W29120828631 @default.
• W2912082863 hasConcept C100094513 @default.
• W2912082863 hasConcept C105702510 @default.
• W2912082863 hasConcept C12554922 @default.
• W2912082863 hasConcept C126838900 @default.
• W2912082863 hasConcept C142724271 @default.
• W2912082863 hasConcept C150903083 @default.
• W2912082863 hasConcept C181199279 @default.
• W2912082863 hasConcept C185592680 @default.
• W2912082863 hasConcept C197957613 @default.
• W2912082863 hasConcept C202751555 @default.
• W2912082863 hasConcept C207001950 @default.
• W2912082863 hasConcept C26291073 @default.
• W2912082863 hasConcept C2775859393 @default.
• W2912082863 hasConcept C2778818243 @default.
• W2912082863 hasConcept C2910059436 @default.
• W2912082863 hasConcept C2910722709 @default.
• W2912082863 hasConcept C29331040 @default.
• W2912082863 hasConcept C529295009 @default.
• W2912082863 hasConcept C534529494 @default.
• W2912082863 hasConcept C55493867 @default.
• W2912082863 hasConcept C71924100 @default.
• W2912082863 hasConcept C86803240 @default.
• W2912082863 hasConcept C87568996 @default.
• W2912082863 hasConcept C95444343 @default.
• W2912082863 hasConceptScore W2912082863C100094513 @default.
• W2912082863 hasConceptScore W2912082863C105702510 @default.
• W2912082863 hasConceptScore W2912082863C12554922 @default.
• W2912082863 hasConceptScore W2912082863C126838900 @default.
• W2912082863 hasConceptScore W2912082863C142724271 @default.
• W2912082863 hasConceptScore W2912082863C150903083 @default.
• W2912082863 hasConceptScore W2912082863C181199279 @default.
• W2912082863 hasConceptScore W2912082863C185592680 @default.
• W2912082863 hasConceptScore W2912082863C197957613 @default.
• W2912082863 hasConceptScore W2912082863C202751555 @default.
• W2912082863 hasConceptScore W2912082863C207001950 @default.
• W2912082863 hasConceptScore W2912082863C26291073 @default.
• W2912082863 hasConceptScore W2912082863C2775859393 @default.
• W2912082863 hasConceptScore W2912082863C2778818243 @default.
• W2912082863 hasConceptScore W2912082863C2910059436 @default.
• W2912082863 hasConceptScore W2912082863C2910722709 @default.
• W2912082863 hasConceptScore W2912082863C29331040 @default.
• W2912082863 hasConceptScore W2912082863C529295009 @default.
• W2912082863 hasConceptScore W2912082863C534529494 @default.
• W2912082863 hasConceptScore W2912082863C55493867 @default.
• W2912082863 hasConceptScore W2912082863C71924100 @default.
• W2912082863 hasConceptScore W2912082863C86803240 @default.
• W2912082863 hasConceptScore W2912082863C87568996 @default.
• W2912082863 hasConceptScore W2912082863C95444343 @default.
• W2912082863 hasIssue "01" @default.
• W2912082863 hasLocation W29120828631 @default.
• W2912082863 hasLocation W29120828632 @default.
• W2912082863 hasLocation W29120828633 @default.
• W2912082863 hasLocation W29120828634 @default.
• W2912082863 hasOpenAccess W2912082863 @default.
• W2912082863 hasPrimaryLocation W29120828631 @default.
• W2912082863 hasRelatedWork W1986273967 @default.
• W2912082863 hasRelatedWork W2072334346 @default.
• W2912082863 hasRelatedWork W2106408380 @default.

• next