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- W2912088281 abstract "Previous clinical trials have reported that vinpocetine can be used for the treatment of cognitive dysfunction. However, its efficacy is still inconclusive. In this systematic review study, we aim to assess its efficacy and safety for the treatment of poststroke cognitive dysfunction (PSCD).We will search the following electronic databases from the inception to the present to evaluate the efficacy and safety of vinpocetine for patients with PSCD. These databases include CENTRAL, EMBASE, MEDILINE, CINAHL, AMED, and four Chinese databases. All randomized controlled trials (RCTs) of vinpocetine for PSCD will be considered for inclusion without the language restrictions. The methodological quality of all included RCTs will be evaluated by the Cochrane risk of bias tool. The 95% confidence intervals will be utilized to calculate the continuous data, the mean difference or standard mean difference, and dichotomous data with risk ratio.The results of this review will be disseminated through peer-reviewed journals. Its results may provide important evidence for the clinical practice, as well as the future studies. It does not require ethical approval, because this systematic review will not involve the individual data.PROSPERO CRD42018115224." @default.
- W2912088281 created "2019-02-21" @default.
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- W2912088281 date "2019-02-01" @default.
- W2912088281 modified "2023-09-25" @default.
- W2912088281 title "Vinpocetine in the treatment of poststroke cognitive dysfunction" @default.
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- W2912088281 doi "https://doi.org/10.1097/md.0000000000013685" @default.
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