Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912095512> ?p ?o ?g. }
- W2912095512 endingPage "562" @default.
- W2912095512 startingPage "562" @default.
- W2912095512 abstract "Our ability to investigate the brain is limited by available technologies that can record biological processes in vivo with suitable spatiotemporal resolution. Advances in optogenetics now enable optical recording and perturbation of central physiological processes within the intact brains of model organisms. By monitoring key signaling molecules noninvasively, we can better appreciate how information is processed and integrated within intact circuits. In this review, we describe recent efforts engineering genetically-encoded fluorescence indicators to monitor neuronal activity. We summarize recent advances of sensors for calcium, potassium, voltage, and select neurotransmitters, focusing on their molecular design, properties, and current limitations. We also highlight impressive applications of these sensors in neuroscience research. We adopt the view that advances in sensor engineering will yield enduring insights on systems neuroscience. Neuroscientists are eager to adopt suitable tools for imaging neural activity in vivo, making this a golden age for engineering optogenetic indicators." @default.
- W2912095512 created "2019-02-21" @default.
- W2912095512 creator A5032185006 @default.
- W2912095512 creator A5040262143 @default.
- W2912095512 creator A5064684076 @default.
- W2912095512 date "2019-02-08" @default.
- W2912095512 modified "2023-10-02" @default.
- W2912095512 title "Advances in Engineering and Application of Optogenetic Indicators for Neuroscience" @default.
- W2912095512 cites W1540301663 @default.
- W2912095512 cites W1542263802 @default.
- W2912095512 cites W1571164133 @default.
- W2912095512 cites W1573732555 @default.
- W2912095512 cites W1575874727 @default.
- W2912095512 cites W1599277155 @default.
- W2912095512 cites W1853680291 @default.
- W2912095512 cites W1954202239 @default.
- W2912095512 cites W1966647250 @default.
- W2912095512 cites W1966927202 @default.
- W2912095512 cites W1967100281 @default.
- W2912095512 cites W1968320713 @default.
- W2912095512 cites W1969195169 @default.
- W2912095512 cites W1969650326 @default.
- W2912095512 cites W1970499295 @default.
- W2912095512 cites W1972784441 @default.
- W2912095512 cites W1975032719 @default.
- W2912095512 cites W1976548894 @default.
- W2912095512 cites W1980338953 @default.
- W2912095512 cites W1982277188 @default.
- W2912095512 cites W1982409013 @default.
- W2912095512 cites W1985458129 @default.
- W2912095512 cites W1988251333 @default.
- W2912095512 cites W1989971979 @default.
- W2912095512 cites W1990076574 @default.
- W2912095512 cites W1991709390 @default.
- W2912095512 cites W1994647098 @default.
- W2912095512 cites W1996807387 @default.
- W2912095512 cites W1999563094 @default.
- W2912095512 cites W2004730560 @default.
- W2912095512 cites W2006709849 @default.
- W2912095512 cites W2013151879 @default.
- W2912095512 cites W2013971421 @default.
- W2912095512 cites W2022185315 @default.
- W2912095512 cites W2023476794 @default.
- W2912095512 cites W2025515174 @default.
- W2912095512 cites W2029261862 @default.
- W2912095512 cites W2037594700 @default.
- W2912095512 cites W2038127888 @default.
- W2912095512 cites W2039409076 @default.
- W2912095512 cites W2041199992 @default.
- W2912095512 cites W2041566506 @default.
- W2912095512 cites W2041656098 @default.
- W2912095512 cites W2043358402 @default.
- W2912095512 cites W2047483303 @default.
- W2912095512 cites W2054344135 @default.
- W2912095512 cites W2055725584 @default.
- W2912095512 cites W2058082904 @default.
- W2912095512 cites W2060384627 @default.
- W2912095512 cites W2062382534 @default.
- W2912095512 cites W2062619493 @default.
- W2912095512 cites W2066757506 @default.
- W2912095512 cites W2067452963 @default.
- W2912095512 cites W2074341964 @default.
- W2912095512 cites W2077374589 @default.
- W2912095512 cites W2079173805 @default.
- W2912095512 cites W2080633827 @default.
- W2912095512 cites W2080778713 @default.
- W2912095512 cites W2085957678 @default.
- W2912095512 cites W2086310064 @default.
- W2912095512 cites W2088304943 @default.
- W2912095512 cites W2089315051 @default.
- W2912095512 cites W2090162100 @default.
- W2912095512 cites W2090389394 @default.
- W2912095512 cites W2091966204 @default.
- W2912095512 cites W2092899524 @default.
- W2912095512 cites W2094933391 @default.
- W2912095512 cites W2096547347 @default.
- W2912095512 cites W2096812577 @default.
- W2912095512 cites W2099209236 @default.
- W2912095512 cites W2101889200 @default.
- W2912095512 cites W2106355804 @default.
- W2912095512 cites W2109234881 @default.
- W2912095512 cites W2115138779 @default.
- W2912095512 cites W2115792839 @default.
- W2912095512 cites W2117573289 @default.
- W2912095512 cites W2120305868 @default.
- W2912095512 cites W2122912327 @default.
- W2912095512 cites W2123300469 @default.
- W2912095512 cites W2123924700 @default.
- W2912095512 cites W2125901663 @default.
- W2912095512 cites W2127780691 @default.
- W2912095512 cites W2129788878 @default.
- W2912095512 cites W2132622695 @default.
- W2912095512 cites W2132892857 @default.
- W2912095512 cites W2134421268 @default.
- W2912095512 cites W2137841176 @default.
- W2912095512 cites W2139587817 @default.
- W2912095512 cites W2143199291 @default.
- W2912095512 cites W2145909957 @default.