Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912111993> ?p ?o ?g. }
- W2912111993 endingPage "1568780" @default.
- W2912111993 startingPage "1568780" @default.
- W2912111993 abstract "Extracellular vesicles (EVs) from a variety of stem cell sources are believed to harbour regenerative capacity, which may be exploited for therapeutic purposes. Because of EV interaction with other soluble secreted factors, EV activity may depend on the employed purification method, which limits cross-study comparisons and therapeutic development. Raman spectroscopy (RS) is a quick and easy method to assess EV purity and composition, giving in-depth biochemical overview on EV preparation. Hereby, we show how this method can be used to characterise EVs isolated from human liver stem cells and bone marrow mesenchymal stem/stromal cells by means of conventional ultracentrifugation (UC) and size exclusion chromatography (SEC) protocols. The obtained EV preparations were demonstrated to be characterised by different degrees of purity and a specific Raman fingerprint that represents both the cell source and the isolation procedure used. Moreover, RS provided useful hints to explore the factors underlying the functional diversity of EV preparations from the same cell source, thus representing a valuable tool to assess EV quality prior to functional assays or therapeutic application." @default.
- W2912111993 created "2019-02-21" @default.
- W2912111993 creator A5045100634 @default.
- W2912111993 creator A5054206882 @default.
- W2912111993 creator A5056727370 @default.
- W2912111993 creator A5058902689 @default.
- W2912111993 creator A5061616796 @default.
- W2912111993 creator A5065128185 @default.
- W2912111993 creator A5090036971 @default.
- W2912111993 date "2019-01-27" @default.
- W2912111993 modified "2023-10-10" @default.
- W2912111993 title "Raman spectroscopy as a quick tool to assess purity of extracellular vesicle preparations and predict their functionality" @default.
- W2912111993 cites W1530729903 @default.
- W2912111993 cites W1581201881 @default.
- W2912111993 cites W1990950572 @default.
- W2912111993 cites W2003079057 @default.
- W2912111993 cites W2021366898 @default.
- W2912111993 cites W2042468850 @default.
- W2912111993 cites W2055424631 @default.
- W2912111993 cites W2063331767 @default.
- W2912111993 cites W2076637458 @default.
- W2912111993 cites W2090597108 @default.
- W2912111993 cites W2093457236 @default.
- W2912111993 cites W2141720233 @default.
- W2912111993 cites W2144026504 @default.
- W2912111993 cites W2146566058 @default.
- W2912111993 cites W2159401023 @default.
- W2912111993 cites W2195965780 @default.
- W2912111993 cites W2207291742 @default.
- W2912111993 cites W2309727226 @default.
- W2912111993 cites W2325493819 @default.
- W2912111993 cites W2417871706 @default.
- W2912111993 cites W2511380210 @default.
- W2912111993 cites W2518923981 @default.
- W2912111993 cites W2540034041 @default.
- W2912111993 cites W2552379881 @default.
- W2912111993 cites W2559936920 @default.
- W2912111993 cites W2561224646 @default.
- W2912111993 cites W2594599876 @default.
- W2912111993 cites W2601301923 @default.
- W2912111993 cites W2612275429 @default.
- W2912111993 cites W2746273252 @default.
- W2912111993 cites W2746710261 @default.
- W2912111993 cites W2752595690 @default.
- W2912111993 cites W2770429106 @default.
- W2912111993 cites W2780538963 @default.
- W2912111993 cites W2791351926 @default.
- W2912111993 cites W2793612642 @default.
- W2912111993 cites W2795774212 @default.
- W2912111993 cites W2802273425 @default.
- W2912111993 cites W2887454857 @default.
- W2912111993 cites W2899868510 @default.
- W2912111993 cites W2900756811 @default.
- W2912111993 doi "https://doi.org/10.1080/20013078.2019.1568780" @default.
- W2912111993 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6352930" @default.
- W2912111993 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30728924" @default.
- W2912111993 hasPublicationYear "2019" @default.
- W2912111993 type Work @default.
- W2912111993 sameAs 2912111993 @default.
- W2912111993 citedByCount "59" @default.
- W2912111993 countsByYear W29121119932019 @default.
- W2912111993 countsByYear W29121119932020 @default.
- W2912111993 countsByYear W29121119932021 @default.
- W2912111993 countsByYear W29121119932022 @default.
- W2912111993 countsByYear W29121119932023 @default.
- W2912111993 crossrefType "journal-article" @default.
- W2912111993 hasAuthorship W2912111993A5045100634 @default.
- W2912111993 hasAuthorship W2912111993A5054206882 @default.
- W2912111993 hasAuthorship W2912111993A5056727370 @default.
- W2912111993 hasAuthorship W2912111993A5058902689 @default.
- W2912111993 hasAuthorship W2912111993A5061616796 @default.
- W2912111993 hasAuthorship W2912111993A5065128185 @default.
- W2912111993 hasAuthorship W2912111993A5090036971 @default.
- W2912111993 hasBestOaLocation W29121119931 @default.
- W2912111993 hasConcept C104317684 @default.
- W2912111993 hasConcept C120665830 @default.
- W2912111993 hasConcept C121332964 @default.
- W2912111993 hasConcept C130316041 @default.
- W2912111993 hasConcept C145059251 @default.
- W2912111993 hasConcept C1491633281 @default.
- W2912111993 hasConcept C16930146 @default.
- W2912111993 hasConcept C171056886 @default.
- W2912111993 hasConcept C185592680 @default.
- W2912111993 hasConcept C198826908 @default.
- W2912111993 hasConcept C20518536 @default.
- W2912111993 hasConcept C28328180 @default.
- W2912111993 hasConcept C2908689518 @default.
- W2912111993 hasConcept C2992929900 @default.
- W2912111993 hasConcept C40003534 @default.
- W2912111993 hasConcept C41625074 @default.
- W2912111993 hasConcept C43617362 @default.
- W2912111993 hasConcept C502942594 @default.
- W2912111993 hasConcept C54689828 @default.
- W2912111993 hasConcept C55493867 @default.
- W2912111993 hasConcept C70721500 @default.
- W2912111993 hasConcept C86803240 @default.
- W2912111993 hasConcept C95444343 @default.
- W2912111993 hasConceptScore W2912111993C104317684 @default.