FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912112687> ?p ?o ?g. }

• W2912112687 endingPage "2697" @default.
• W2912112687 startingPage "2686" @default.
• W2912112687 abstract "Although the EEG slow wave of sleep is typically considered to be a hallmark of nonrapid eye movement (NREM) sleep, recent work in mice has shown that slow waves can also occur in REM sleep. Here, we investigated the presence and cortical distribution of negative delta (1-4 Hz) waves in human REM sleep by analyzing high-density EEG sleep recordings obtained in 28 healthy subjects. We identified two clusters of delta waves with distinctive properties: (1) a frontal-central cluster characterized by ∼2.5-3.0 Hz, relatively large, notched delta waves (so-called sawtooth waves) that tended to occur in bursts, were associated with increased gamma activity and rapid eye movements (EMs), and upon source modeling displayed an occipital-temporal and a frontal-central component and (2) a medial-occipital cluster characterized by more isolated, slower (<2 Hz), and smaller waves that were not associated with rapid EMs, displayed a negative correlation with gamma activity, and were also found in NREM sleep. Therefore, delta waves are an integral part of REM sleep in humans and the two identified subtypes (sawtooth and medial-occipital slow waves) may reflect distinct generation mechanisms and functional roles. Sawtooth waves, which are exclusive to REM sleep, share many characteristics with ponto-geniculo-occipital waves described in animals and may represent the human equivalent or a closely related event, whereas medial-occipital slow waves appear similar to NREM sleep slow waves.SIGNIFICANCE STATEMENT The EEG slow wave is typically considered a hallmark of nonrapid eye movement (NREM) sleep, but recent work in mice has shown that it can also occur in REM sleep. By analyzing high-density EEG recordings collected in healthy adult individuals, we show that REM sleep is characterized by prominent delta waves also in humans. In particular, we identified two distinctive clusters of delta waves with different properties: a frontal-central cluster characterized by faster, activating sawtooth waves that share many characteristics with ponto-geniculo-occipital waves described in animals and a medial-occipital cluster containing slow waves that are more similar to NREM sleep slow waves. These findings indicate that REM sleep is a spatially and temporally heterogeneous state and may contribute to explaining its known functional and phenomenological properties." @default.
• W2912112687 created "2019-02-21" @default.
• W2912112687 creator A5001381023 @default.
• W2912112687 creator A5026710897 @default.
• W2912112687 creator A5036909430 @default.
• W2912112687 creator A5052608017 @default.
• W2912112687 creator A5059674840 @default.
• W2912112687 creator A5080685139 @default.
• W2912112687 date "2019-02-08" @default.
• W2912112687 modified "2023-10-14" @default.
• W2912112687 title "Regional Delta Waves In Human Rapid Eye Movement Sleep" @default.
• W2912112687 cites W1524345901 @default.
• W2912112687 cites W1540311052 @default.
• W2912112687 cites W1544261274 @default.
• W2912112687 cites W1577987636 @default.
• W2912112687 cites W1643594517 @default.
• W2912112687 cites W1706861413 @default.
• W2912112687 cites W1853766545 @default.
• W2912112687 cites W1949141612 @default.
• W2912112687 cites W1967493737 @default.
• W2912112687 cites W1970478805 @default.
• W2912112687 cites W1970593689 @default.
• W2912112687 cites W197066864 @default.
• W2912112687 cites W1971355925 @default.
• W2912112687 cites W1973117088 @default.
• W2912112687 cites W1975476104 @default.
• W2912112687 cites W1977078688 @default.
• W2912112687 cites W1977647750 @default.
• W2912112687 cites W1977881365 @default.
• W2912112687 cites W1987356423 @default.
• W2912112687 cites W1987851823 @default.
• W2912112687 cites W1988220777 @default.
• W2912112687 cites W1990466236 @default.
• W2912112687 cites W1993049273 @default.
• W2912112687 cites W1993971128 @default.
• W2912112687 cites W1997119714 @default.
• W2912112687 cites W1999214946 @default.
• W2912112687 cites W1999470896 @default.
• W2912112687 cites W2000608289 @default.
• W2912112687 cites W2005813957 @default.
• W2912112687 cites W2010724870 @default.
• W2912112687 cites W2022022341 @default.
• W2912112687 cites W2022246567 @default.
• W2912112687 cites W2022476141 @default.
• W2912112687 cites W2024307331 @default.
• W2912112687 cites W2024446380 @default.
• W2912112687 cites W2024509615 @default.
• W2912112687 cites W2025511037 @default.
• W2912112687 cites W2030760182 @default.
• W2912112687 cites W2032822262 @default.
• W2912112687 cites W2039029351 @default.
• W2912112687 cites W2039812775 @default.
• W2912112687 cites W2047223899 @default.
• W2912112687 cites W2060392742 @default.
• W2912112687 cites W2065324213 @default.
• W2912112687 cites W2069354959 @default.
• W2912112687 cites W2073295713 @default.
• W2912112687 cites W2089843837 @default.
• W2912112687 cites W2093471901 @default.
• W2912112687 cites W2097953961 @default.
• W2912112687 cites W2107824087 @default.
• W2912112687 cites W2116464478 @default.
• W2912112687 cites W2128040542 @default.
• W2912112687 cites W2128495200 @default.
• W2912112687 cites W2138790588 @default.
• W2912112687 cites W2145859699 @default.
• W2912112687 cites W2157080893 @default.
• W2912112687 cites W2159577274 @default.
• W2912112687 cites W2167014329 @default.
• W2912112687 cites W2271201640 @default.
• W2912112687 cites W2277019871 @default.
• W2912112687 cites W2295626065 @default.
• W2912112687 cites W2320283089 @default.
• W2912112687 cites W2400322909 @default.
• W2912112687 cites W2409152886 @default.
• W2912112687 cites W2412773808 @default.
• W2912112687 cites W2419318340 @default.
• W2912112687 cites W2419448230 @default.
• W2912112687 cites W2521853867 @default.
• W2912112687 cites W2582259160 @default.
• W2912112687 cites W2588000528 @default.
• W2912112687 cites W2607177050 @default.
• W2912112687 cites W2618141244 @default.
• W2912112687 cites W2752044543 @default.
• W2912112687 cites W2762256573 @default.
• W2912112687 cites W2803420737 @default.
• W2912112687 cites W2806383879 @default.
• W2912112687 cites W2888122022 @default.
• W2912112687 cites W2891183344 @default.
• W2912112687 cites W2914117531 @default.
• W2912112687 cites W2951480721 @default.
• W2912112687 cites W3026928252 @default.
• W2912112687 cites W37929333 @default.
• W2912112687 cites W4295831928 @default.
• W2912112687 doi "https://doi.org/10.1523/jneurosci.2298-18.2019" @default.
• W2912112687 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6445986" @default.
• W2912112687 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30737310" @default.
• W2912112687 hasPublicationYear "2019" @default.

• next