Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912123407> ?p ?o ?g. }
- W2912123407 endingPage "160" @default.
- W2912123407 startingPage "148" @default.
- W2912123407 abstract "The clinical use of deep brain stimulation (DBS) is among the most important advances in the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly measure pathological brain activity and can deliver adjustable stimulation for therapeutic effect in neurological and psychiatric disorders correlated with dysfunctional circuitry. The development of DBS has opened new opportunities to access and interrogate malfunctioning brain circuits and to test the therapeutic potential of regulating the output of these circuits in a broad range of disorders. Despite the success and rapid adoption of DBS, crucial questions remain, including which brain areas should be targeted and in which patients. This Review considers how DBS has facilitated advances in our understanding of how circuit malfunction can lead to brain disorders and outlines the key unmet challenges and future directions in the DBS field. Determining the next steps in DBS science will help to define the future role of this technology in the development of novel therapeutics for the most challenging disorders affecting the human brain." @default.
- W2912123407 created "2019-02-21" @default.
- W2912123407 creator A5010362418 @default.
- W2912123407 creator A5029802910 @default.
- W2912123407 creator A5034219333 @default.
- W2912123407 creator A5037934561 @default.
- W2912123407 creator A5044208679 @default.
- W2912123407 creator A5062092154 @default.
- W2912123407 creator A5067783855 @default.
- W2912123407 creator A5071124477 @default.
- W2912123407 creator A5078475739 @default.
- W2912123407 creator A5083835604 @default.
- W2912123407 creator A5087477752 @default.
- W2912123407 creator A5087852701 @default.
- W2912123407 creator A5090019636 @default.
- W2912123407 date "2019-01-25" @default.
- W2912123407 modified "2023-10-14" @default.
- W2912123407 title "Deep brain stimulation: current challenges and future directions" @default.
- W2912123407 cites W108424361 @default.
- W2912123407 cites W1534323731 @default.
- W2912123407 cites W1575604476 @default.
- W2912123407 cites W1625906005 @default.
- W2912123407 cites W1665095741 @default.
- W2912123407 cites W1863394635 @default.
- W2912123407 cites W1933009444 @default.
- W2912123407 cites W1965965542 @default.
- W2912123407 cites W1966449086 @default.
- W2912123407 cites W1969578547 @default.
- W2912123407 cites W1972682560 @default.
- W2912123407 cites W1973719999 @default.
- W2912123407 cites W1977172001 @default.
- W2912123407 cites W1978574256 @default.
- W2912123407 cites W1979072695 @default.
- W2912123407 cites W1982843701 @default.
- W2912123407 cites W1984229466 @default.
- W2912123407 cites W1987810063 @default.
- W2912123407 cites W1987874253 @default.
- W2912123407 cites W1989739279 @default.
- W2912123407 cites W1990280414 @default.
- W2912123407 cites W1993936388 @default.
- W2912123407 cites W1995226234 @default.
- W2912123407 cites W1995782021 @default.
- W2912123407 cites W2000929270 @default.
- W2912123407 cites W2000931238 @default.
- W2912123407 cites W2002758208 @default.
- W2912123407 cites W2008123743 @default.
- W2912123407 cites W2010753407 @default.
- W2912123407 cites W2014786844 @default.
- W2912123407 cites W2018378637 @default.
- W2912123407 cites W2018830020 @default.
- W2912123407 cites W2018864423 @default.
- W2912123407 cites W2019941448 @default.
- W2912123407 cites W2021782736 @default.
- W2912123407 cites W2022335135 @default.
- W2912123407 cites W2023619652 @default.
- W2912123407 cites W2024400089 @default.
- W2912123407 cites W2025850077 @default.
- W2912123407 cites W2025929754 @default.
- W2912123407 cites W2028163833 @default.
- W2912123407 cites W2029754211 @default.
- W2912123407 cites W2030428255 @default.
- W2912123407 cites W2030727295 @default.
- W2912123407 cites W2038780394 @default.
- W2912123407 cites W2039156670 @default.
- W2912123407 cites W2039619083 @default.
- W2912123407 cites W2044523049 @default.
- W2912123407 cites W2045526770 @default.
- W2912123407 cites W2050731195 @default.
- W2912123407 cites W2052504911 @default.
- W2912123407 cites W2056843995 @default.
- W2912123407 cites W2057917506 @default.
- W2912123407 cites W2058126381 @default.
- W2912123407 cites W2058307954 @default.
- W2912123407 cites W2059387706 @default.
- W2912123407 cites W2063594532 @default.
- W2912123407 cites W2063630341 @default.
- W2912123407 cites W2072517893 @default.
- W2912123407 cites W2072810539 @default.
- W2912123407 cites W2073718251 @default.
- W2912123407 cites W2074402500 @default.
- W2912123407 cites W2082851956 @default.
- W2912123407 cites W2083845601 @default.
- W2912123407 cites W2084809245 @default.
- W2912123407 cites W2087599430 @default.
- W2912123407 cites W2087909380 @default.
- W2912123407 cites W2091447671 @default.
- W2912123407 cites W2096577216 @default.
- W2912123407 cites W2099426010 @default.
- W2912123407 cites W2101801005 @default.
- W2912123407 cites W2102861453 @default.
- W2912123407 cites W2104951220 @default.
- W2912123407 cites W2105885719 @default.
- W2912123407 cites W2106956384 @default.
- W2912123407 cites W2107610137 @default.
- W2912123407 cites W2110106419 @default.
- W2912123407 cites W2112704483 @default.
- W2912123407 cites W2114622428 @default.
- W2912123407 cites W2116498912 @default.