Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912123990> ?p ?o ?g. }
- W2912123990 endingPage "365" @default.
- W2912123990 startingPage "355" @default.
- W2912123990 abstract "Urinary bladder cancer is the ninth most common cancer in developed countries with poor prognosis and outcome for the patient due to the challenging diagnosis and limited treatment possibilities. Bladder cancer arises mainly from urothelial cells lining the lumen. Urothelial cells form a three- to five-layered urothelium, which maintains the blood-urine barrier. The carbohydrates that cover the apical surface of superficial urothelial cells, i.e. umbrella cells, are crucial for this function. The composition of the carbohydrate covering is altered during urothelial cancer transformation. These bladder cancer-associated carbohydrate changes are a promising field for diagnosis, therapy and management. Lectins, which are carbohydrate-binding proteins, can be used to detect subtle alterations in carbohydrate composition during urothelial cancer transformation. Extensive research into various lectin applications has already been conducted, but the results are often contradictory and confusing. None of these applications have reached clinical trials. We review the literature and discuss (i) current bladder cancer management, (ii) lectin-based assays for detection of various cancer subtypes, (iii) lectin-based strategies for innovative bladder cancer treatment and finally (iv) lectins in nanotheranostics for personalized bladder cancer management." @default.
- W2912123990 created "2019-02-21" @default.
- W2912123990 creator A5028357334 @default.
- W2912123990 creator A5038830254 @default.
- W2912123990 creator A5067774820 @default.
- W2912123990 date "2019-02-12" @default.
- W2912123990 modified "2023-09-23" @default.
- W2912123990 title "Lectins as possible tools for improved urinary bladder cancer management" @default.
- W2912123990 cites W118551320 @default.
- W2912123990 cites W145329232 @default.
- W2912123990 cites W1502708974 @default.
- W2912123990 cites W1503410058 @default.
- W2912123990 cites W1516253144 @default.
- W2912123990 cites W1638424324 @default.
- W2912123990 cites W1752019264 @default.
- W2912123990 cites W1854386788 @default.
- W2912123990 cites W1879193160 @default.
- W2912123990 cites W1909797527 @default.
- W2912123990 cites W1911301755 @default.
- W2912123990 cites W1938656015 @default.
- W2912123990 cites W1963658052 @default.
- W2912123990 cites W1971175072 @default.
- W2912123990 cites W1975260420 @default.
- W2912123990 cites W1975701041 @default.
- W2912123990 cites W1977950944 @default.
- W2912123990 cites W1988243620 @default.
- W2912123990 cites W1991019518 @default.
- W2912123990 cites W1993747943 @default.
- W2912123990 cites W1998637109 @default.
- W2912123990 cites W1999414270 @default.
- W2912123990 cites W1999768858 @default.
- W2912123990 cites W2003701302 @default.
- W2912123990 cites W2010064879 @default.
- W2912123990 cites W2011178846 @default.
- W2912123990 cites W2019099142 @default.
- W2912123990 cites W2022166140 @default.
- W2912123990 cites W2023379963 @default.
- W2912123990 cites W2026496911 @default.
- W2912123990 cites W2030196475 @default.
- W2912123990 cites W2036178456 @default.
- W2912123990 cites W2039493610 @default.
- W2912123990 cites W2040824338 @default.
- W2912123990 cites W2045206991 @default.
- W2912123990 cites W2045676777 @default.
- W2912123990 cites W2045749627 @default.
- W2912123990 cites W2047491492 @default.
- W2912123990 cites W2053915783 @default.
- W2912123990 cites W2054571853 @default.
- W2912123990 cites W2055957478 @default.
- W2912123990 cites W2057340503 @default.
- W2912123990 cites W2058367450 @default.
- W2912123990 cites W2065710500 @default.
- W2912123990 cites W2066415888 @default.
- W2912123990 cites W2068108952 @default.
- W2912123990 cites W2071031876 @default.
- W2912123990 cites W2079835368 @default.
- W2912123990 cites W2083954684 @default.
- W2912123990 cites W2084764446 @default.
- W2912123990 cites W2086626831 @default.
- W2912123990 cites W2089142394 @default.
- W2912123990 cites W2090739196 @default.
- W2912123990 cites W2091629981 @default.
- W2912123990 cites W2094296002 @default.
- W2912123990 cites W2110995574 @default.
- W2912123990 cites W2116748469 @default.
- W2912123990 cites W2117502386 @default.
- W2912123990 cites W2117832286 @default.
- W2912123990 cites W2120021002 @default.
- W2912123990 cites W2122620614 @default.
- W2912123990 cites W2124570812 @default.
- W2912123990 cites W2130848408 @default.
- W2912123990 cites W2131042553 @default.
- W2912123990 cites W2131946032 @default.
- W2912123990 cites W2133274933 @default.
- W2912123990 cites W2135567092 @default.
- W2912123990 cites W2143453528 @default.
- W2912123990 cites W2145068212 @default.
- W2912123990 cites W2151781453 @default.
- W2912123990 cites W2161633777 @default.
- W2912123990 cites W2163387042 @default.
- W2912123990 cites W2163928870 @default.
- W2912123990 cites W2165911190 @default.
- W2912123990 cites W2166749901 @default.
- W2912123990 cites W2168083201 @default.
- W2912123990 cites W2170127039 @default.
- W2912123990 cites W2170705825 @default.
- W2912123990 cites W2173598215 @default.
- W2912123990 cites W2244035233 @default.
- W2912123990 cites W2301685087 @default.
- W2912123990 cites W2398637237 @default.
- W2912123990 cites W2432449008 @default.
- W2912123990 cites W2513534081 @default.
- W2912123990 cites W2543031791 @default.
- W2912123990 cites W2557269122 @default.
- W2912123990 cites W2573152477 @default.
- W2912123990 cites W2583984203 @default.
- W2912123990 cites W2595325397 @default.
- W2912123990 cites W2604737947 @default.