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• W2912126403 abstract "Abstract Multimodal strategies have significantly improved the outcomes for patients with central nervous system nongerminomatous germ cell tumors. Two large cooperative group studies have recently reported much improved outcomes compared with historical series. However, a substantial proportion of patients still attain inadequate responses to initial chemotherapy prior to irradiation, with adverse impact upon survival; optimal induction chemotherapy regimens and radiotherapy strategies are as yet unidentified. Outcomes for patients with relapsed disease remain poor. There is an obvious need to incorporate molecular studies within prospective clinical trials that will likely lead to the incorporation of targeted, more effective future treatment strategies." @default.
• W2912126403 created "2019-02-21" @default.
• W2912126403 creator A5016558887 @default.
• W2912126403 creator A5068257880 @default.
• W2912126403 creator A5072346018 @default.
• W2912126403 creator A5088462429 @default.
• W2912126403 date "2019-02-15" @default.
• W2912126403 modified "2023-09-25" @default.
• W2912126403 title "Critical review of the management of primary central nervous nongerminomatous germ cell tumors" @default.
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