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- W2912128716 endingPage "276" @default.
- W2912128716 startingPage "251" @default.
- W2912128716 abstract "A new era of innovative research is transforming the study of cardiovascular pathobiology from static histopathology research to dynamic mechanistic cell and molecular biology investigation. The development of reliable cell culture methods to harvest, maintain, and study the cells of the cardiovascular system now allows for the investigation of dynamic structure and function relationships at the cellular and molecular levels. Stem/precursor/pluripotential populations of cells have been identified and isolated from both humans and experimental animal models that are both renewable and differentiate along cardiovascular lineages to regulate regeneration and repair. Bioactive molecules are being identified as diagnostic biomarkers and therapeutic targets. New knowledge on pathogenesis is being gained from both in vivo and in vitro molecular studies especially where genes are modified and gene expression is manipulated. These advances bring new hope to be able to prevent and/or diagnose cardiovascular diseases early and to repair injured cardiovascular tissue and restore normal function by using precision medicine to target pathogenic molecules and pathways and to utilize cell therapy and tissue engineering to regenerate cardiovascular tissue." @default.
- W2912128716 created "2019-02-21" @default.
- W2912128716 creator A5025369816 @default.
- W2912128716 date "2018-01-01" @default.
- W2912128716 modified "2023-09-25" @default.
- W2912128716 title "Molecular Basis of Cardiovascular Disease" @default.
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