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• W2912128840 abstract "Objective: To assess the clinical usefulness of adding MINGO as a nutritional supplement to the daily dietary needs of X-linked Dystonia Parkinsonism (XDP) patients, thereby increasing their BMI. Background: X-linked dystonia parkinsonism (XDP) occurs primarily in Filipino males and is characterized by neurodegenerative dystonia and parkinsonism. XDP patients suffer from severe nutritional loss due to their dysphagia and movement disorder. MINGO is a supplement consisting of local ingredients such as moringa, rice and mung beans, which can be added to any type of edible paste, food, and liquid. Design/Methods: We enrolled 50 clinically diagnosed X-linked Dystonia-Parkinsonism men in an open-labeled prospective randomized-controlled trial in Capiz, Philippines to examine the effects of 480 calories of MINGO food supplementation on their body mass index (BMI). The mean BMI taken in 2 week intervals for 3 months was used as the primary endpoint. Secondary endpoints include the mid-upper arm circumference (MUAC) taken at monthly intervals, hospitalizations and death. We used a mixed effects linear regression model using R to analyze the data. Results: The mean BMI in the MINGO group at week 12 was 19.07 [95% CI: 17.83–20.31] while the mean BMI in the control group at week 12 was 17.95 [95% CI, 16.90–18.99]. The mean MUAC in the MINGO group at week 12 was 26.69 [95% CI, 25.41–27.97] while the mean MUAC in the control group was 26.62 [25.03–28.18]. After correcting for baseline BMI, BFM score, Eat 10 score, and MGH SST score (as fixed and random effects), we found no statistically significant difference between the BMI in the MINGO group and the control group. Conclusions: Although BMI and MUAC were found to be higher in the MINGO group compared to the control group, these effects have not been found to be statistically significant after adjusting for BFM score, Eat 10 score, and MGH SST score. Study Supported by: Sunshine Care Foundation Disclosure: Dr. Acuna has nothing to disclose. Dr. Solinap has nothing to disclose. Dr. De Guzman has nothing to disclose. Dr. Ang has nothing to disclose. Dr. Go has nothing to disclose." @default.
• W2912128840 created "2019-02-21" @default.
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• W2912128840 date "2018-04-10" @default.
• W2912128840 modified "2023-09-26" @default.
• W2912128840 title "Mingo Supplemental Trial: An Open-Label Prospective Randomized Controlled Trial in X-linked Dystonia Parkinsonism Patients in the Province of Capiz, Philippines (P5.054)" @default.
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