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• W2912132067 abstract "It is a matter of current debate whether the bone marrow is a hub for circulating memory T lymphocytes and/or the home of resident memory T lymphocytes. Here we demonstrate for CD69+ murine CD8+ , and CD69+ murine and human CD4+ memory T lymphocytes of the bone marrow, making up between 30 and 60% of bone marrow memory T lymphocytes, that they express the gene expression signature of tissue-resident memory T lymphocytes. This suggests that a substantial proportion of bone marrow memory T lymphocytes are resident. It adds to previous evidence that bone marrow memory T cells are resting in terms of mobility and proliferation, and maintain exclusive long-term memory to distinct, systemic antigens." @default.
• W2912132067 created "2019-02-21" @default.
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• W2912132067 date "2019-01-30" @default.
• W2912132067 modified "2023-10-15" @default.
• W2912132067 title "CD69 ⁺ memory T lymphocytes of the bone marrow and spleen express the signature transcripts of tissue‐resident memory T lymphocytes" @default.
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• W2912132067 doi "https://doi.org/10.1002/eji.201847982" @default.
• W2912132067 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6563480" @default.
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