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- W2912150224 abstract "Hypersensitivity reactions to iodinated contrast media (ICM) are a common problem and can cause anaphylaxis. The clinical utility of skin testing for ICM reactions is uncertain. Retrospective analysis was done of data from 47 patients (18 males, 29 females, average age 55 years) with a history of hypersensitivity reactions to ICM referred to Vilnius University Hospital from 2014 to 2017 . Skin prick (SPT) and intradermal tests (IDM) with ICM were performed according to the EAACI guidelines including assessment of ICM iohexol, iopromide, diatrizoate, iodixanol, and iopamidol. Cutaneous symptoms were most common (55.6%) followed by cardiovascular symptoms (17.5%), respiratory symptoms (9.5%) and gastrointestinal symptoms (7.9%) with some (9.5%) nonspecific symptoms. SPT were negative in all patients. Seven out of 47 (14.9%) patients had positive IDT. 3 patients had positive reactions to 2 or more ICM. Reactions to ICM were not more severe in patients with positive skin test results. Clinical patterns of IDT positive patients did not differ from patients with negative skin tests. Five of 23 patients tested less than one year after the reaction had a positive IDT, while 2 of 24 patients having a reaction to ICM more than 1 year prior were positive (p>0.05). Allergy to ICM was seldom produced positive IDT in patients with suspected ICM hypersensivity ICM. Cutaneous symptoms were most frequent form of ICM hypersensitivity reaction irregardless of skin test results. with positive and negative skin tests." @default.
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- W2912150224 date "2019-02-01" @default.
- W2912150224 modified "2023-10-14" @default.
- W2912150224 title "Utility of Skin Tests for Diagnosis of Hypersensitivity Reactions to Iodinated Contrast Media" @default.
- W2912150224 doi "https://doi.org/10.1016/j.jaci.2018.12.182" @default.
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