Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912154879> ?p ?o ?g. }
- W2912154879 endingPage "2334" @default.
- W2912154879 startingPage "2322" @default.
- W2912154879 abstract "Background: Gastric cancer is a major malignancy that has high incidence rates worldwide. Approximately 30% of patients with gastric cancer have progressed into advanced stages at the time of diagnosis. Chemotherapy is the standard-of-care for most advanced gastric cancer and elicits variable responses among patients. Personalized chemotherapy based on genetic information of individual patients with gastric cancer has gained increasing attention among oncologists for guiding chemotherapeutic regimens. Methods: This review summarizes recent progress of individualized chemotherapy in gastric cancer guided by pharmacogenomics. Variable medical research search engines, such as PubMed, Google Scholar, SpringerLink and ScienceDirect, were used to retrieve related literature. Only peerreviewed journal articles were selected for further analyses. Results and Conclusion: The efficiency of chemotherapy in patients with gastric cancer is not only determined by chemotherapeutic drugs but is also directly and indirectly influenced by functionally correlative genes. Individual gene alteration or polymorphism remarkably affects patients’ responses to particular chemotherapy. Most studies have focused on the influence of single-gene alteration on a selected drug, and only a few works explored the interaction between therapeutics and a panel of genes. Individualized chemotherapy regimens guided by a genetic survey of a multiple-gene panel are expected to remarkably improve the treatment efficacy in patients with advanced gastric cancer and may become the new standard for personalizing chemotherapy for gastric cancer in the near future." @default.
- W2912154879 created "2019-02-21" @default.
- W2912154879 creator A5025647936 @default.
- W2912154879 creator A5056364613 @default.
- W2912154879 creator A5066928428 @default.
- W2912154879 creator A5086533693 @default.
- W2912154879 date "2020-04-29" @default.
- W2912154879 modified "2023-09-24" @default.
- W2912154879 title "Progress of Individualized Chemotherapy for Gastric Carcinoma Under the Guidance of Genetic Testing" @default.
- W2912154879 cites W1490813547 @default.
- W2912154879 cites W1852205457 @default.
- W2912154879 cites W1896195310 @default.
- W2912154879 cites W1977022507 @default.
- W2912154879 cites W1979685373 @default.
- W2912154879 cites W1980168308 @default.
- W2912154879 cites W1981140460 @default.
- W2912154879 cites W1987459099 @default.
- W2912154879 cites W1988622751 @default.
- W2912154879 cites W2001596915 @default.
- W2912154879 cites W2004629780 @default.
- W2912154879 cites W2006943192 @default.
- W2912154879 cites W2012550724 @default.
- W2912154879 cites W2013891525 @default.
- W2912154879 cites W2014403549 @default.
- W2912154879 cites W2014622726 @default.
- W2912154879 cites W2018483384 @default.
- W2912154879 cites W2021223798 @default.
- W2912154879 cites W2021363911 @default.
- W2912154879 cites W2031083378 @default.
- W2912154879 cites W2033359380 @default.
- W2912154879 cites W2041051519 @default.
- W2912154879 cites W2042619042 @default.
- W2912154879 cites W2044230523 @default.
- W2912154879 cites W2046479872 @default.
- W2912154879 cites W2048342842 @default.
- W2912154879 cites W2049015983 @default.
- W2912154879 cites W2050719579 @default.
- W2912154879 cites W2053371603 @default.
- W2912154879 cites W2055437752 @default.
- W2912154879 cites W2085520037 @default.
- W2912154879 cites W2089528860 @default.
- W2912154879 cites W2094792156 @default.
- W2912154879 cites W2094838876 @default.
- W2912154879 cites W2104477572 @default.
- W2912154879 cites W2104637985 @default.
- W2912154879 cites W2109465247 @default.
- W2912154879 cites W2116692581 @default.
- W2912154879 cites W2125526025 @default.
- W2912154879 cites W2128447158 @default.
- W2912154879 cites W2131276940 @default.
- W2912154879 cites W2131348261 @default.
- W2912154879 cites W2141325183 @default.
- W2912154879 cites W2145480986 @default.
- W2912154879 cites W2145995826 @default.
- W2912154879 cites W2148126204 @default.
- W2912154879 cites W2157250910 @default.
- W2912154879 cites W2163709149 @default.
- W2912154879 cites W2163885210 @default.
- W2912154879 cites W2164631611 @default.
- W2912154879 cites W2165715420 @default.
- W2912154879 cites W2166716850 @default.
- W2912154879 cites W2167702905 @default.
- W2912154879 cites W2167766673 @default.
- W2912154879 cites W2171168074 @default.
- W2912154879 cites W2171551314 @default.
- W2912154879 cites W2295950157 @default.
- W2912154879 cites W2409439172 @default.
- W2912154879 cites W2511498189 @default.
- W2912154879 cites W2574548326 @default.
- W2912154879 cites W2580960033 @default.
- W2912154879 cites W2588112660 @default.
- W2912154879 cites W2593012676 @default.
- W2912154879 cites W2622970549 @default.
- W2912154879 cites W2638829242 @default.
- W2912154879 cites W2660041470 @default.
- W2912154879 cites W2735573310 @default.
- W2912154879 cites W2754915601 @default.
- W2912154879 cites W2761557154 @default.
- W2912154879 cites W2765798696 @default.
- W2912154879 cites W2767613374 @default.
- W2912154879 cites W2771217224 @default.
- W2912154879 cites W2775088862 @default.
- W2912154879 cites W2899846936 @default.
- W2912154879 cites W4296465570 @default.
- W2912154879 cites W803341175 @default.
- W2912154879 doi "https://doi.org/10.2174/0929867326666190204123101" @default.
- W2912154879 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30714518" @default.
- W2912154879 hasPublicationYear "2020" @default.
- W2912154879 type Work @default.
- W2912154879 sameAs 2912154879 @default.
- W2912154879 citedByCount "6" @default.
- W2912154879 countsByYear W29121548792021 @default.
- W2912154879 countsByYear W29121548792022 @default.
- W2912154879 countsByYear W29121548792023 @default.
- W2912154879 crossrefType "journal-article" @default.
- W2912154879 hasAuthorship W2912154879A5025647936 @default.
- W2912154879 hasAuthorship W2912154879A5056364613 @default.
- W2912154879 hasAuthorship W2912154879A5066928428 @default.