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- W2912157499 abstract "Abstract Hand preference is a conspicuous variation in human behaviour, with a worldwide proportion of around 90% of people preferring to use the right hand for many tasks, and 10% the left hand. We used the large cohort of the UK biobank (~500,000 participants) to study possible relations between early life factors and adult hand preference. The probability of being left-handed was affected by the year and location of birth, likely due to cultural effects. In addition, hand preference was affected by birthweight, being part of a multiple birth, season of birth, breastfeeding, and sex, with each effect remaining significant after accounting for all others. Analysis of genome-wide genotype data showed that left-handedness was very weakly heritable, but shared no genetic basis with birthweight. Although on average left-handers and right-handers differed for a number of early life factors, all together these factors had only a minimal predictive value for individual hand preference." @default.
- W2912157499 created "2019-02-21" @default.
- W2912157499 creator A5001227180 @default.
- W2912157499 creator A5034733299 @default.
- W2912157499 creator A5047361673 @default.
- W2912157499 date "2019-01-24" @default.
- W2912157499 modified "2023-10-16" @default.
- W2912157499 title "A large-scale population study of early life factors influencing left-handedness" @default.
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- W2912157499 doi "https://doi.org/10.1038/s41598-018-37423-8" @default.
- W2912157499 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6345846" @default.
- W2912157499 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30679750" @default.
- W2912157499 hasPublicationYear "2019" @default.
- W2912157499 type Work @default.
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