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- W2912162874 abstract "Laryngeal tuberculosis (LT) is a rare disease. The therapy for LT is easy but the diagnosis remains a challenge for the pathologist and the laryngologist because of the absence of specific signs. The objective was to analyze the epidemiological and pathological profiles of LT cases in Dakar (Senegal) with a view to better understand this pathology. This study was a retrospective and descriptive of LT cases diagnosed in pathology laboratories in Senegal during five years (2011-2015). The LT was found in 9 cases. The mean age at diagnosis was 41.9 years (18/58) without sex predominance (sex-ratio = 0.8). Tobacco intoxication (3/9), tuberculosis contagion (1/9), HIV immunodepression (2/9), and diabetes (1/9) were the various risk factors found. Dysphonia was a constant symptom (9/9) associated with dysphagia (2/9) and cervical adenopathy (1/9). The macroscopic presentation was tumoral-like (7/9) and erythematosus and fibrinoid (2/9). The LT was of glottic seat in all the cases (9/9) with participation on top-glottic in two of the cases. The biopsy was performed in all patients. It reported tuberculous granuloma in four cases (4/9), tuberculoid granuloma in one case (1/9), and chronic lymphocytic laryngitis in four cases (4/9). CT-scan of the lungs was pathological in five patients (5/9). Evolution was favorable in all cases under conventional tuberculosis treatment over a period of six months. The diagnosis of LT requires a high collaboration between the laryngologist and the pathologist.La tuberculose laryngée (TL) est une affection rare de diagnostic difficile à cause de l'absence de signes spécifiques. L'objectif de cette étude rétrospective était d'analyser les profils épidémiocliniques et anatomopathologiques des cas de TL diagnostiqués dans un laboratoire d'anatomie pathologique du Sénégal. Il s'agissait d'une étude rétrospective et descriptive des cas de TL sur cinq ans (2011–2015). La TL a été retrouvée dans neuf cas. L'âge moyen au diagnostic était de 41,9 ans (18/58) sans prédominance de sexe (sex-ratio = 0,8). Le tabagisme (3/9), le contage tuberculeux (1/9), l'immunodépression au VIH (2/9) et le diabète (1/9) étaient les différents facteurs de risque retrouvés. La dysphonie était un symptôme constant (9/9), accompagnée d'une dysphagie (2/9) et d'adénopathies cervicales (1/9). L'aspect macroscopique était pseudotumoral (7/9) et érythématoblanchâtre (2/9). La TL était de siège glottique dans tous les cas (9/9), avec participation sus-glottique dans deux cas. La biopsie systématique notait un granulome tuberculeux dans quatre cas (4/9), un granulome tuberculoïde dans un cas (1/9) et une laryngite chronique lymphocytaire dans quatre cas. L'évolution était favorable dans tous les cas sous traitement médical. Le diagnostic de la TL nécessite une collaboration parfaite et étroite entre l'otorhinolaryngologue et le pathologiste." @default.
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- W2912162874 date "2018-02-28" @default.
- W2912162874 modified "2023-09-27" @default.
- W2912162874 title "La tuberculose laryngée diagnostiquée dans un laboratoire d’anatomie pathologique du Sénégal (2011–2015)" @default.
- W2912162874 doi "https://doi.org/10.3166/bspe-2018-0010" @default.
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