FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912166039> ?p ?o ?g. }

• W2912166039 abstract "Ya-Samarn-Phlae (YaSP) is a traditional Thai polyherbal formula for the treatment of chronic wounds. Although its ethanol extract has been proven to possess several wound-related biological activities, there is no scientific information available for the infused oil of YaSP, which is its traditionally prepared form. This present study therefore aimed to evaluate the efficacy of different infused oils obtained from either fresh or oven-dried herbal parts of YaSP (F-YaSP and D-YaSP) against biofilms of Pseudomonas aeruginosa, which reside in chronic wounds. Its main active herbal component, Garcinia mangostana (F-GM and D-GM), as well as α-mangostin were also tested in this study. All infused oils significantly inhibited the biofilm formation of P. aeruginosa with a percentage of reduction ranging from 50 to 90%. Visualization of the inhibition of biofilm development was confirmed using scanning electron and atomic force microscopes. All tested agents resulted in a reduction in the mean average roughness of the biofilm, whereas only treating with D-YaSP, D-GM, and α-mangostin led to a decrease in both peak height and peak-valley height. MTT reduction assays revealed that the metabolic activity of P. aeruginosa mature biofilms decreased considerably up to 50% after only 3 h of incubation and after only 9 h of exposure to D-YaSP. Confocal laser scanning micrographs illustrated that a maximum biofilm eradication was found when treated with the extracts for 3 h, whereas the biomass, the average thickness, maximum thickness, and the surface to volume ratio of the treated biofilm was reduced after up to 18 h of contact time. It can be concluded that D-YaSP can effectively inhibit biofilm formation and eradicate mature biofilms of P. aeruginosa. It should be noted that G. mangostana and α-mangostin contribute in YaSP as principle active agents for anti-biofilm efficacy." @default.
• W2912166039 created "2019-02-21" @default.
• W2912166039 creator A5018158090 @default.
• W2912166039 creator A5027190640 @default.
• W2912166039 creator A5031768589 @default.
• W2912166039 creator A5038684387 @default.
• W2912166039 creator A5039403970 @default.
• W2912166039 creator A5052545300 @default.
• W2912166039 creator A5057978019 @default.
• W2912166039 creator A5060964743 @default.
• W2912166039 creator A5079280983 @default.
• W2912166039 creator A5083654971 @default.
• W2912166039 date "2019-03-01" @default.
• W2912166039 modified "2023-09-24" @default.
• W2912166039 title "Effects of a traditional Thai polyherbal medicine ‘Ya-Samarn-Phlae’ as a natural anti-biofilm agent against Pseudomonas aeruginosa" @default.
• W2912166039 cites W1577305427 @default.
• W2912166039 cites W1980037982 @default.
• W2912166039 cites W1983740472 @default.
• W2912166039 cites W1994749876 @default.
• W2912166039 cites W2000514402 @default.
• W2912166039 cites W2002069786 @default.
• W2912166039 cites W2024353993 @default.
• W2912166039 cites W2035741837 @default.
• W2912166039 cites W2036220014 @default.
• W2912166039 cites W2047304512 @default.
• W2912166039 cites W2051766882 @default.
• W2912166039 cites W2073717190 @default.
• W2912166039 cites W2081016978 @default.
• W2912166039 cites W2091072231 @default.
• W2912166039 cites W2092961312 @default.
• W2912166039 cites W2101307155 @default.
• W2912166039 cites W2104878413 @default.
• W2912166039 cites W2109453910 @default.
• W2912166039 cites W2119724838 @default.
• W2912166039 cites W2123196970 @default.
• W2912166039 cites W2142322164 @default.
• W2912166039 cites W2157550671 @default.
• W2912166039 cites W2162335168 @default.
• W2912166039 cites W2190150208 @default.
• W2912166039 cites W2339278178 @default.
• W2912166039 cites W2423557796 @default.
• W2912166039 cites W2472384654 @default.
• W2912166039 cites W2514164911 @default.
• W2912166039 cites W2544160761 @default.
• W2912166039 cites W2549535358 @default.
• W2912166039 cites W2587696950 @default.
• W2912166039 cites W2601271221 @default.
• W2912166039 cites W2609591691 @default.
• W2912166039 cites W2766452553 @default.
• W2912166039 doi "https://doi.org/10.1016/j.micpath.2019.01.036" @default.
• W2912166039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30684637" @default.
• W2912166039 hasPublicationYear "2019" @default.
• W2912166039 type Work @default.
• W2912166039 sameAs 2912166039 @default.
• W2912166039 citedByCount "6" @default.
• W2912166039 countsByYear W29121660392020 @default.
• W2912166039 countsByYear W29121660392021 @default.
• W2912166039 countsByYear W29121660392022 @default.
• W2912166039 crossrefType "journal-article" @default.
• W2912166039 hasAuthorship W2912166039A5018158090 @default.
• W2912166039 hasAuthorship W2912166039A5027190640 @default.
• W2912166039 hasAuthorship W2912166039A5031768589 @default.
• W2912166039 hasAuthorship W2912166039A5038684387 @default.
• W2912166039 hasAuthorship W2912166039A5039403970 @default.
• W2912166039 hasAuthorship W2912166039A5052545300 @default.
• W2912166039 hasAuthorship W2912166039A5057978019 @default.
• W2912166039 hasAuthorship W2912166039A5060964743 @default.
• W2912166039 hasAuthorship W2912166039A5079280983 @default.
• W2912166039 hasAuthorship W2912166039A5083654971 @default.
• W2912166039 hasConcept C136229726 @default.
• W2912166039 hasConcept C185592680 @default.
• W2912166039 hasConcept C202751555 @default.
• W2912166039 hasConcept C2777637488 @default.
• W2912166039 hasConcept C2780783641 @default.
• W2912166039 hasConcept C2909826119 @default.
• W2912166039 hasConcept C2988511132 @default.
• W2912166039 hasConcept C31903555 @default.
• W2912166039 hasConcept C523546767 @default.
• W2912166039 hasConcept C54355233 @default.
• W2912166039 hasConcept C55493867 @default.
• W2912166039 hasConcept C556039675 @default.
• W2912166039 hasConcept C58123911 @default.
• W2912166039 hasConcept C71924100 @default.
• W2912166039 hasConcept C86803240 @default.
• W2912166039 hasConcept C88412794 @default.
• W2912166039 hasConcept C89423630 @default.
• W2912166039 hasConceptScore W2912166039C136229726 @default.
• W2912166039 hasConceptScore W2912166039C185592680 @default.
• W2912166039 hasConceptScore W2912166039C202751555 @default.
• W2912166039 hasConceptScore W2912166039C2777637488 @default.
• W2912166039 hasConceptScore W2912166039C2780783641 @default.
• W2912166039 hasConceptScore W2912166039C2909826119 @default.
• W2912166039 hasConceptScore W2912166039C2988511132 @default.
• W2912166039 hasConceptScore W2912166039C31903555 @default.
• W2912166039 hasConceptScore W2912166039C523546767 @default.
• W2912166039 hasConceptScore W2912166039C54355233 @default.
• W2912166039 hasConceptScore W2912166039C55493867 @default.
• W2912166039 hasConceptScore W2912166039C556039675 @default.
• W2912166039 hasConceptScore W2912166039C58123911 @default.
• W2912166039 hasConceptScore W2912166039C71924100 @default.

• next