FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912169624> ?p ?o ?g. }

• W2912169624 abstract "Ricinoleic acid is a high-value hydroxy fatty acid with broad industrial applications. Hiptage benghalensis seed oil contains a high amount of ricinoleic acid (~ 80%) and represents an emerging source of this unusual fatty acid. However, the mechanism of ricinoleic acid accumulation in H. benghalensis is yet to be explored at the molecular level, which hampers the exploration of its potential in ricinoleic acid production. To explore the molecular mechanism of ricinoleic acid biosynthesis and regulation, H. benghalensis seeds were harvested at five developing stages (13, 16, 19, 22, and 25 days after pollination) for lipid analysis. The results revealed that the rapid accumulation of ricinoleic acid occurred at the early–mid-seed development stages (16–22 days after pollination). Subsequently, the gene transcription profiles of the developing seeds were characterized via a comprehensive transcriptome analysis with second-generation sequencing and single-molecule real-time sequencing. Differential expression patterns were identified in 12,555 transcripts, including 71 enzymes in lipid metabolic pathways, 246 putative transcription factors (TFs) and 124 long noncoding RNAs (lncRNAs). Twelve genes involved in diverse lipid metabolism pathways, including fatty acid biosynthesis and modification (hydroxylation), lipid traffic, triacylglycerol assembly, acyl editing and oil-body formation, displayed high expression levels and consistent expression patterns with ricinoleic acid accumulation in the developing seeds, suggesting their primary roles in ricinoleic acid production. Subsequent co-expression network analysis identified 57 TFs and 35 lncRNAs, which are putatively involved in the regulation of ricinoleic acid biosynthesis. The transcriptome data were further validated by analyzing the expression profiles of key enzyme-encoding genes, TFs and lncRNAs with quantitative real-time PCR. Finally, a network of genes associated with ricinoleic acid accumulation in H. benghalensis was established. This study was the first step toward the understating of the molecular mechanisms of ricinoleic acid biosynthesis and oil accumulation in H. benghalensis seeds and identified a pool of novel genes regulating ricinoleic acid accumulation. The results set a foundation for developing H. benghalensis into a novel ricinoleic acid feedstock at the transcriptomic level and provided valuable candidate genes for improving ricinoleic acid production in other plants." @default.
• W2912169624 created "2019-02-21" @default.
• W2912169624 creator A5017671951 @default.
• W2912169624 creator A5018205720 @default.
• W2912169624 creator A5037024906 @default.
• W2912169624 creator A5054223932 @default.
• W2912169624 creator A5059114372 @default.
• W2912169624 date "2019-01-21" @default.
• W2912169624 modified "2023-10-12" @default.
• W2912169624 title "Identification of genes associated with ricinoleic acid accumulation in Hiptage benghalensis via transcriptome analysis" @default.
• W2912169624 cites W1490781569 @default.
• W2912169624 cites W1854051914 @default.
• W2912169624 cites W1898050893 @default.
• W2912169624 cites W1968078797 @default.
• W2912169624 cites W1970445394 @default.
• W2912169624 cites W1972679549 @default.
• W2912169624 cites W1978523917 @default.
• W2912169624 cites W1987848454 @default.
• W2912169624 cites W1995838394 @default.
• W2912169624 cites W2008002548 @default.
• W2912169624 cites W2016254413 @default.
• W2912169624 cites W2016650856 @default.
• W2912169624 cites W2018637188 @default.
• W2912169624 cites W2018718778 @default.
• W2912169624 cites W2021387989 @default.
• W2912169624 cites W2021842094 @default.
• W2912169624 cites W2022318444 @default.
• W2912169624 cites W2025256487 @default.
• W2912169624 cites W2026468967 @default.
• W2912169624 cites W2031269596 @default.
• W2912169624 cites W2032553363 @default.
• W2912169624 cites W2042999607 @default.
• W2912169624 cites W2043734532 @default.
• W2912169624 cites W2046107485 @default.
• W2912169624 cites W2048809272 @default.
• W2912169624 cites W2051076583 @default.
• W2912169624 cites W2054645010 @default.
• W2912169624 cites W2055465845 @default.
• W2912169624 cites W2061320568 @default.
• W2912169624 cites W2067335713 @default.
• W2912169624 cites W2077248502 @default.
• W2912169624 cites W2087773181 @default.
• W2912169624 cites W2108357601 @default.
• W2912169624 cites W2109869496 @default.
• W2912169624 cites W2112689789 @default.
• W2912169624 cites W2116232319 @default.
• W2912169624 cites W2129606791 @default.
• W2912169624 cites W2136877208 @default.
• W2912169624 cites W2144809163 @default.
• W2912169624 cites W2147526198 @default.
• W2912169624 cites W2147559640 @default.
• W2912169624 cites W2149195408 @default.
• W2912169624 cites W2202601463 @default.
• W2912169624 cites W2296996623 @default.
• W2912169624 cites W2300045580 @default.
• W2912169624 cites W2307760237 @default.
• W2912169624 cites W2313540090 @default.
• W2912169624 cites W2461226401 @default.
• W2912169624 cites W2468927214 @default.
• W2912169624 cites W2474587044 @default.
• W2912169624 cites W2735934473 @default.
• W2912169624 cites W2763514816 @default.
• W2912169624 cites W2767673683 @default.
• W2912169624 cites W2779308640 @default.
• W2912169624 cites W2793972788 @default.
• W2912169624 cites W2804988498 @default.
• W2912169624 cites W2813459012 @default.
• W2912169624 cites W2884846596 @default.
• W2912169624 cites W2894226727 @default.
• W2912169624 cites W4242561105 @default.
• W2912169624 cites W85131412 @default.
• W2912169624 cites W929098118 @default.
• W2912169624 doi "https://doi.org/10.1186/s13068-019-1358-2" @default.
• W2912169624 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6340187" @default.
• W2912169624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30679955" @default.
• W2912169624 hasPublicationYear "2019" @default.
• W2912169624 type Work @default.
• W2912169624 sameAs 2912169624 @default.
• W2912169624 citedByCount "16" @default.
• W2912169624 countsByYear W29121696242020 @default.
• W2912169624 countsByYear W29121696242021 @default.
• W2912169624 countsByYear W29121696242022 @default.
• W2912169624 countsByYear W29121696242023 @default.
• W2912169624 crossrefType "journal-article" @default.
• W2912169624 hasAuthorship W2912169624A5017671951 @default.
• W2912169624 hasAuthorship W2912169624A5018205720 @default.
• W2912169624 hasAuthorship W2912169624A5037024906 @default.
• W2912169624 hasAuthorship W2912169624A5054223932 @default.
• W2912169624 hasAuthorship W2912169624A5059114372 @default.
• W2912169624 hasBestOaLocation W29121696241 @default.
• W2912169624 hasConcept C104317684 @default.
• W2912169624 hasConcept C150194340 @default.
• W2912169624 hasConcept C162317418 @default.
• W2912169624 hasConcept C2778229996 @default.
• W2912169624 hasConcept C2779072430 @default.
• W2912169624 hasConcept C4733338 @default.
• W2912169624 hasConcept C543025807 @default.
• W2912169624 hasConcept C55493867 @default.
• W2912169624 hasConcept C86803240 @default.
• W2912169624 hasConceptScore W2912169624C104317684 @default.

• next