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- W2912182143 abstract "Abstract Dysbiosis in the genital tract or gut microbiome can be associated with endometriosis. We sampled vaginal, cervical and gut microbiota from 14 women with histology proven stage 3/4 endometriosis and 14 healthy controls. The V3 and V4 regions of the 16S rRNA gene were amplified following the 16S Metagenomic Sequencing Library Preparation. Despite overall similar vaginal, cervical and intestinal microbiota composition between stage 3/4 endometriosis group and controls, we observed differences at genus level. The complete absence of Atopobium in the vaginal and cervical microbiota of the stage 3/4 endometriosis group was noteworthy. In the cervical microbiota, Gardnerella , Streptococcus , Escherichia , Shigella , and Ureoplasma, all of which contain potentially pathogenic species , were increased in stage 3/4 endometriosis. More women in the stage 3/4 endometriosis group had Shigella/Escherichia dominant stool microbiome. Further studies can clarify whether the association is causal, and whether dysbiosis leads to endometriosis or endometriosis leads to dysbiosis." @default.
- W2912182143 created "2019-02-21" @default.
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- W2912182143 date "2019-02-18" @default.
- W2912182143 modified "2023-10-17" @default.
- W2912182143 title "The Endobiota Study: Comparison of Vaginal, Cervical and Gut Microbiota Between Women with Stage 3/4 Endometriosis and Healthy Controls" @default.
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- W2912182143 doi "https://doi.org/10.1038/s41598-019-39700-6" @default.
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