Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912191967> ?p ?o ?g. }
- W2912191967 abstract "The enteric nervous system controls a variety of gastrointestinal functions including intestinal motility. The minimal neuronal circuit necessary to direct peristalsis is well-characterized but several intestinal regions display also other motility patterns for which the underlying circuits and connectivity schemes that coordinate the transition between those patterns are poorly understood. We investigated whether in regions with a richer palette of motility patterns, the underlying nerve circuits reflect this complexity. Using Ca2+ imaging, we determined the location and response fingerprint of large populations of enteric neurons upon focal network stimulation. Complemented by neuronal tracing and volumetric reconstructions of synaptic contacts, this shows that the multifunctional proximal colon requires specific additional circuit components as compared to the distal colon, where peristalsis is the predominant motility pattern. Our study reveals that motility control is hard-wired in the enteric neural networks and that circuit complexity matches the motor pattern portfolio of specific intestinal regions." @default.
- W2912191967 created "2019-02-21" @default.
- W2912191967 creator A5023613754 @default.
- W2912191967 creator A5031135262 @default.
- W2912191967 creator A5040886525 @default.
- W2912191967 creator A5044812020 @default.
- W2912191967 creator A5062214651 @default.
- W2912191967 creator A5081531120 @default.
- W2912191967 date "2019-02-12" @default.
- W2912191967 modified "2023-10-10" @default.
- W2912191967 title "Regional complexity in enteric neuron wiring reflects diversity of motility patterns in the mouse large intestine" @default.
- W2912191967 cites W1481268917 @default.
- W2912191967 cites W1511113293 @default.
- W2912191967 cites W1590648103 @default.
- W2912191967 cites W1596500417 @default.
- W2912191967 cites W1597434328 @default.
- W2912191967 cites W1600808102 @default.
- W2912191967 cites W1949635207 @default.
- W2912191967 cites W1954898011 @default.
- W2912191967 cites W1965121027 @default.
- W2912191967 cites W1969356438 @default.
- W2912191967 cites W1973015864 @default.
- W2912191967 cites W1974584320 @default.
- W2912191967 cites W1975655744 @default.
- W2912191967 cites W1981367331 @default.
- W2912191967 cites W1989470236 @default.
- W2912191967 cites W1990736267 @default.
- W2912191967 cites W1994217270 @default.
- W2912191967 cites W1995927317 @default.
- W2912191967 cites W2003426511 @default.
- W2912191967 cites W2004578280 @default.
- W2912191967 cites W2010484899 @default.
- W2912191967 cites W2016769131 @default.
- W2912191967 cites W2022170160 @default.
- W2912191967 cites W2025461874 @default.
- W2912191967 cites W2025930431 @default.
- W2912191967 cites W2026902665 @default.
- W2912191967 cites W2041914927 @default.
- W2912191967 cites W2046078347 @default.
- W2912191967 cites W2047437054 @default.
- W2912191967 cites W2048495038 @default.
- W2912191967 cites W2063601395 @default.
- W2912191967 cites W2066827684 @default.
- W2912191967 cites W2066859126 @default.
- W2912191967 cites W2071309858 @default.
- W2912191967 cites W2072578266 @default.
- W2912191967 cites W2075570424 @default.
- W2912191967 cites W2080266577 @default.
- W2912191967 cites W2092704146 @default.
- W2912191967 cites W2093774651 @default.
- W2912191967 cites W2100432967 @default.
- W2912191967 cites W2115508185 @default.
- W2912191967 cites W2124571312 @default.
- W2912191967 cites W2126728858 @default.
- W2912191967 cites W2139802677 @default.
- W2912191967 cites W2147566771 @default.
- W2912191967 cites W2149191617 @default.
- W2912191967 cites W2152593612 @default.
- W2912191967 cites W2157955426 @default.
- W2912191967 cites W2158989951 @default.
- W2912191967 cites W2168723618 @default.
- W2912191967 cites W2169411929 @default.
- W2912191967 cites W2218825212 @default.
- W2912191967 cites W2255620227 @default.
- W2912191967 cites W2301119123 @default.
- W2912191967 cites W2317137223 @default.
- W2912191967 cites W2346146107 @default.
- W2912191967 cites W2435239913 @default.
- W2912191967 cites W2523252530 @default.
- W2912191967 cites W2540134543 @default.
- W2912191967 cites W2557978136 @default.
- W2912191967 cites W2608547780 @default.
- W2912191967 cites W2614402207 @default.
- W2912191967 cites W2760757413 @default.
- W2912191967 cites W2768401404 @default.
- W2912191967 cites W2794244195 @default.
- W2912191967 cites W2803573552 @default.
- W2912191967 cites W2803823517 @default.
- W2912191967 cites W2949693884 @default.
- W2912191967 cites W2993304598 @default.
- W2912191967 doi "https://doi.org/10.7554/elife.42914" @default.
- W2912191967 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6391068" @default.
- W2912191967 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30747710" @default.
- W2912191967 hasPublicationYear "2019" @default.
- W2912191967 type Work @default.
- W2912191967 sameAs 2912191967 @default.
- W2912191967 citedByCount "54" @default.
- W2912191967 countsByYear W29121919672019 @default.
- W2912191967 countsByYear W29121919672020 @default.
- W2912191967 countsByYear W29121919672021 @default.
- W2912191967 countsByYear W29121919672022 @default.
- W2912191967 countsByYear W29121919672023 @default.
- W2912191967 crossrefType "journal-article" @default.
- W2912191967 hasAuthorship W2912191967A5023613754 @default.
- W2912191967 hasAuthorship W2912191967A5031135262 @default.
- W2912191967 hasAuthorship W2912191967A5040886525 @default.
- W2912191967 hasAuthorship W2912191967A5044812020 @default.
- W2912191967 hasAuthorship W2912191967A5062214651 @default.
- W2912191967 hasAuthorship W2912191967A5081531120 @default.
- W2912191967 hasBestOaLocation W29121919671 @default.