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• W2912195449 abstract "<h3>BACKGROUND AND PURPOSE:</h3> In recent years, effort has been made to study 3D biometry as a method for fetal brain assessment. In this study, we aimed to compare brain volumes of fetuses with cytomegalovirus infection and noninfected controls. Also, we wanted to assess whether there is a correlation to their neurodevelopmental outcome as observed after several years. <h3>MATERIALS AND METHODS:</h3> A retrospective cohort study examined MR imaging brain scans of 42 fetuses (at 30–34 weeks9 gestational age) that were diagnosed with intrauterine cytomegalovirus infection. Volumetric measurements of 6 structures were assessed using a semiautomated designated program and were compared with a control group of 50 fetuses. Data collected included prenatal history and MR imaging and sonographic and neurodevelopmental follow-up. <h3>RESULTS:</h3> We found that all brain volumes measured were smaller in the cytomegalovirus-infected group and that there was a correlation between smaller cerebellar volume and lower Vineland II Adaptive Behavior Scales questionnaire scores, especially in the fields of daily living and communication skills. <h3>CONCLUSIONS:</h3> In this study, we found that brain volumes are affected by intrauterine cytomegalovirus infection and that it has a developmental prognostic meaning. Such information, which should be supported by further research, may help clinicians further analyze imaging data to treat and make a better assessment of these fetuses." @default.
• W2912195449 created "2019-02-21" @default.
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• W2912195449 date "2019-02-01" @default.
• W2912195449 modified "2023-10-07" @default.
• W2912195449 title "Volumetric MRI Study of the Brain in Fetuses with Intrauterine Cytomegalovirus Infection and Its Correlation to Neurodevelopmental Outcome" @default.
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• W2912195449 doi "https://doi.org/10.3174/ajnr.a5948" @default.
• W2912195449 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7028642" @default.
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