FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912212188> ?p ?o ?g. }

• W2912212188 endingPage "1798" @default.
• W2912212188 startingPage "1789" @default.
• W2912212188 abstract "BACKGROUND Using platelet additive solution (PAS) to dilute fibrinogen during long‐term cold storage of platelets (PLTs) decreases PLT activation and increases functional PLT shelf life. We performed a randomized, paired study to assess the in vitro quality of PLTs stored in the cold in T‐PAS+ for up to 18 days evaluated against PLTs stored under currently allowable conditions (5‐day room temperature–stored PLTs [RTP] and 3‐day cold‐stored PLTs [CSP]). STUDY DESIGN AND METHODS PLTs were collected from healthy volunteers (n = 10) and diluted to 65% T‐PAS+/35% plasma before cold storage. Double‐dose apheresis PLTs (in 100% plasma) were collected from the same donors and split into two bags (one bag RTP, one bag CSP). All bags were sampled on the day of collection (Day 0). CSP and RTP bags were sampled on Days 3 and 5, respectively. T‐PAS+ samples were assessed on Days 3, 5, 14, 16, and 18 of storage for metabolism, hemostatic function, and activation. RESULTS After 18 days of storage in T‐PAS+, pH was 6.71 ± 0.04, PLT count was comparable to Day 3 CSP, PLT function (aggregation and clot strength) was comparable to Day 5 RTP, and PLT activation was significantly increased. CONCLUSION Refrigerated PLTs stored in T‐PAS+ for 18 days met FDA pH standards. Functional metrics suggest activity of T‐PAS+‐stored PLTs and the potential to contribute to hemostasis throughout 18 days of storage. Extending the shelf life of PLTs would increase access to hemostatic resuscitation for bleeding patients in military and civilian settings." @default.
• W2912212188 created "2019-02-21" @default.
• W2912212188 creator A5003941493 @default.
• W2912212188 creator A5028974660 @default.
• W2912212188 creator A5029858181 @default.
• W2912212188 creator A5030156969 @default.
• W2912212188 creator A5041029867 @default.
• W2912212188 creator A5053562103 @default.
• W2912212188 creator A5060195587 @default.
• W2912212188 creator A5062407449 @default.
• W2912212188 creator A5072317817 @default.
• W2912212188 creator A5079156233 @default.
• W2912212188 creator A5087505554 @default.
• W2912212188 date "2019-02-06" @default.
• W2912212188 modified "2023-10-17" @default.
• W2912212188 title "An in vitro pilot study of apheresis platelets collected on Trima Accel system and stored in T‐PAS+ solution at refrigeration temperature (1‐6°C)" @default.
• W2912212188 cites W130048390 @default.
• W2912212188 cites W1533084826 @default.
• W2912212188 cites W1851039170 @default.
• W2912212188 cites W1979626640 @default.
• W2912212188 cites W1994660709 @default.
• W2912212188 cites W2010738078 @default.
• W2912212188 cites W2030809178 @default.
• W2912212188 cites W2047192693 @default.
• W2912212188 cites W2061027528 @default.
• W2912212188 cites W2117913181 @default.
• W2912212188 cites W2119958273 @default.
• W2912212188 cites W2236786177 @default.
• W2912212188 cites W2264372496 @default.
• W2912212188 cites W2303583306 @default.
• W2912212188 cites W2376909924 @default.
• W2912212188 cites W2416947623 @default.
• W2912212188 cites W2474519573 @default.
• W2912212188 cites W2622634772 @default.
• W2912212188 cites W2753139574 @default.
• W2912212188 cites W2794803954 @default.
• W2912212188 cites W64750453 @default.
• W2912212188 doi "https://doi.org/10.1111/trf.15150" @default.
• W2912212188 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30725491" @default.
• W2912212188 hasPublicationYear "2019" @default.
• W2912212188 type Work @default.
• W2912212188 sameAs 2912212188 @default.
• W2912212188 citedByCount "18" @default.
• W2912212188 countsByYear W29122121882019 @default.
• W2912212188 countsByYear W29122121882020 @default.
• W2912212188 countsByYear W29122121882021 @default.
• W2912212188 countsByYear W29122121882022 @default.
• W2912212188 countsByYear W29122121882023 @default.
• W2912212188 crossrefType "journal-article" @default.
• W2912212188 hasAuthorship W2912212188A5003941493 @default.
• W2912212188 hasAuthorship W2912212188A5028974660 @default.
• W2912212188 hasAuthorship W2912212188A5029858181 @default.
• W2912212188 hasAuthorship W2912212188A5030156969 @default.
• W2912212188 hasAuthorship W2912212188A5041029867 @default.
• W2912212188 hasAuthorship W2912212188A5053562103 @default.
• W2912212188 hasAuthorship W2912212188A5060195587 @default.
• W2912212188 hasAuthorship W2912212188A5062407449 @default.
• W2912212188 hasAuthorship W2912212188A5072317817 @default.
• W2912212188 hasAuthorship W2912212188A5079156233 @default.
• W2912212188 hasAuthorship W2912212188A5087505554 @default.
• W2912212188 hasConcept C141071460 @default.
• W2912212188 hasConcept C144027150 @default.
• W2912212188 hasConcept C16685009 @default.
• W2912212188 hasConcept C185592680 @default.
• W2912212188 hasConcept C203014093 @default.
• W2912212188 hasConcept C2776738589 @default.
• W2912212188 hasConcept C2778589496 @default.
• W2912212188 hasConcept C2779867487 @default.
• W2912212188 hasConcept C2908988968 @default.
• W2912212188 hasConcept C2988529969 @default.
• W2912212188 hasConcept C71924100 @default.
• W2912212188 hasConcept C86803240 @default.
• W2912212188 hasConcept C89560881 @default.
• W2912212188 hasConceptScore W2912212188C141071460 @default.
• W2912212188 hasConceptScore W2912212188C144027150 @default.
• W2912212188 hasConceptScore W2912212188C16685009 @default.
• W2912212188 hasConceptScore W2912212188C185592680 @default.
• W2912212188 hasConceptScore W2912212188C203014093 @default.
• W2912212188 hasConceptScore W2912212188C2776738589 @default.
• W2912212188 hasConceptScore W2912212188C2778589496 @default.
• W2912212188 hasConceptScore W2912212188C2779867487 @default.
• W2912212188 hasConceptScore W2912212188C2908988968 @default.
• W2912212188 hasConceptScore W2912212188C2988529969 @default.
• W2912212188 hasConceptScore W2912212188C71924100 @default.
• W2912212188 hasConceptScore W2912212188C86803240 @default.
• W2912212188 hasConceptScore W2912212188C89560881 @default.
• W2912212188 hasIssue "5" @default.
• W2912212188 hasLocation W29122121881 @default.
• W2912212188 hasLocation W29122121882 @default.
• W2912212188 hasOpenAccess W2912212188 @default.
• W2912212188 hasPrimaryLocation W29122121881 @default.
• W2912212188 hasRelatedWork W1594908460 @default.
• W2912212188 hasRelatedWork W1957345840 @default.
• W2912212188 hasRelatedWork W2003074829 @default.
• W2912212188 hasRelatedWork W2038370621 @default.
• W2912212188 hasRelatedWork W2092069358 @default.
• W2912212188 hasRelatedWork W2270760819 @default.
• W2912212188 hasRelatedWork W2325807190 @default.

• next