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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912221205> ?p ?o ?g. }

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• W2912221205 startingPage "657" @default.
• W2912221205 abstract "In Epstein-Barr virus (EBV)-infected epithelial cancers, BamHI A rightward transcript (BART) miRNAs are highly expressed. However, only a few target genes of BART miRNAs have been investigated. Our mRNA microarray data showed that DKK1 was markedly down-regulated in EBV-associated gastric carcinoma (EBVaGC) cells. Using luciferase reporter assay we tested whether miR-BART10-3p regulates DKK1 by directly targeting the 3'-UTR of DKK1 mRNA. We observed that miR-BART10-3p transfection decreased DKK1 expression, while an LNA inhibitor of miR-BART10-3p (LNA-miR-BART10-3p(i)) increased DKK1 expression. Furthermore, miR-BART10-3p and siDKK1 promoted cell proliferation and migration. In contrast, transfecting GC cells with LNA-miR-BART10-3p(i) or DKK1 over expression vector suppressed cell proliferation and migration. Our results suggest that miR-BART10-3p may be involved in the tumor progression of EBVaGC by targeting DKK1." @default.
• W2912221205 created "2019-02-21" @default.
• W2912221205 creator A5018123597 @default.
• W2912221205 creator A5090782082 @default.
• W2912221205 date "2019-01-01" @default.
• W2912221205 modified "2023-10-14" @default.
• W2912221205 title "EBV miR-BART10-3p Promotes Cell Proliferation and Migration by Targeting DKK1" @default.
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• W2912221205 doi "https://doi.org/10.7150/ijbs.30099" @default.
• W2912221205 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6367590" @default.
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• W2912221205 hasPublicationYear "2019" @default.
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