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- W2912221914 abstract "Current guidelines recommend steroids for induction of remission in all children diagnosed with autoimmune hepatitis regardless of the clinical presentation. In this report, we describe our experience in treating selected asymptomatic children with autoimmune hepatitis using a steroid-free regimen; this treatment strategy was safe and effective in inducing remission. Current guidelines recommend steroids for induction of remission in all children diagnosed with autoimmune hepatitis regardless of the clinical presentation. In this report, we describe our experience in treating selected asymptomatic children with autoimmune hepatitis using a steroid-free regimen; this treatment strategy was safe and effective in inducing remission. Steroid free treatment in autoimmune hepatitis: Is azathioprine monotherapy truly a viable option to obtain remission?The Journal of PediatricsVol. 210PreviewWe read with interest the article by Wehrman et al.1 We agree that adverse effects of prednisone therapy have a significant physical and psychological impact in children and adolescents with autoimmune hepatitis (AIH). However, a reliable steroid-free regimen already exists using cyclosporine (CSA) instead of prednisone to induce and maintain remission.2 Long-term treatment with CSA has been confirmed to be effective and safe; no major side effects were seen during prolonged follow-up, which was up to 20 years in some patients. Full-Text PDF" @default.
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- W2912221914 date "2019-04-01" @default.
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- W2912221914 title "Steroid Free Treatment of Autoimmune Hepatitis in Selected Children" @default.
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- W2912221914 doi "https://doi.org/10.1016/j.jpeds.2018.12.070" @default.
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