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- W2912226781 endingPage "2842" @default.
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- W2912226781 abstract "We describe the 3-iodopropyl acetal moiety as a simple cleavable unit that undergoes acid catalyzed hydrolysis to liberate HI (p Ka ∼ -10) and acrolein stoichiometrically. Integrating this unit into linear and network polymers gives a class of macromolecules that undergo a new mechanism of degradation with an acid amplified, sigmoidal rate. This trigger-responsive self-amplified degradable polymer undergoes accelerated rate of degradation and agent release." @default.
- W2912226781 created "2019-02-21" @default.
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- W2912226781 date "2019-01-30" @default.
- W2912226781 modified "2023-10-16" @default.
- W2912226781 title "Acid-Triggered, Acid-Generating, and Self-Amplifying Degradable Polymers" @default.
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- W2912226781 doi "https://doi.org/10.1021/jacs.8b07705" @default.
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