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• W2912233344 abstract "Depressive symptoms are common in patients with coronary artery disease (CAD) and are associated with an unfavourable outcome. Establishing prognostic patient profiles prior to the beginning of mental health care may facilitate higher efficacy of targeted interventions. The aim of the current study was to identify sociodemographic and somatic predictors of depression outcome among depressed patients with CAD. Based on the dataset of the multicentre SPIRR-CAD randomised controlled trial (n = 570 patients with CAD and ≥ 8 points on the Hospital Anxiety and Depression Scale (HADS)), 141 potential sociodemographic and somatic predictors of the change in the HADS-D depression score from baseline to 18-month-follow-up were derived in two different ways. We screened for univariable association with response, using either analysis of (co)variance or logistic regression, respectively, both adjusted for baseline HADS-D value and treatment group. To guard against overfitting, multivariable association was evaluated by a linear or binomial (generalised) linear model with lasso regularisation, a machine learning approach. Outcome measures were the change in continuous HADS-D depression scores, as well as three established binary criteria. The Charlson Comorbidity Index (CCI) was calculated to assess possible influences of comorbidities on our results and was also entered in our machine learning approach. Higher age (p = 0.002), unknown previous myocardial infarction (p = 0.013), and a higher heart rate variability during numeracy tests (p = .020) were univariably associated with a favourable depression outcome, whereas hyperuricemia (p ≤ 0.003), higher triglycerides (p = 0.014), NYHA class III (p ≤ 0.028), state after resuscitation (p ≤ 0.042), intake of thyroid hormones (p = 0.007), antidiabetic drugs (p = 0.015), analgesic drugs (p = 0.027), beta blockers (p = 0.035), uric acid drugs (p ≤ 0.039), and anticholinergic drugs (p = 0.045) were associated with an adverse effect on the HADS-D depression score. In all analyses, no significant differences between study arms could be found and physical comorbidities also had no significant influence on our results. Our findings may contribute to identification of somatic and sociodemographic predictors of depression outcome in patients with CAD. The unexpected effects of specific medication require further clarification and further research is needed to establish a causal association between depression outcome and our predictors. www.clinicaltrials.gov NCT00705965 (registered 27th of June, 2008). www.isrctn.com ISRCTN76240576 (registered 27th of March, 2008)." @default.
• W2912233344 created "2019-02-21" @default.
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• W2912233344 date "2019-02-04" @default.
• W2912233344 modified "2023-10-02" @default.
• W2912233344 title "Somatic and sociodemographic predictors of depression outcome among depressed patients with coronary artery disease - a secondary analysis of the SPIRR-CAD study" @default.
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• W2912233344 cites W190196949 @default.
• W2912233344 cites W1971156384 @default.
• W2912233344 cites W1978814746 @default.
• W2912233344 cites W1979492245 @default.
• W2912233344 cites W1981020864 @default.
• W2912233344 cites W1990999690 @default.
• W2912233344 cites W1992470868 @default.
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• W2912233344 cites W2002968897 @default.
• W2912233344 cites W2003982930 @default.
• W2912233344 cites W2012691107 @default.
• W2912233344 cites W2013735941 @default.
• W2912233344 cites W2018490234 @default.
• W2912233344 cites W2023504648 @default.
• W2912233344 cites W2030450271 @default.
• W2912233344 cites W2034258479 @default.
• W2912233344 cites W2034630933 @default.
• W2912233344 cites W2040649786 @default.
• W2912233344 cites W2043424001 @default.
• W2912233344 cites W2064166778 @default.
• W2912233344 cites W2084158133 @default.
• W2912233344 cites W2087795228 @default.
• W2912233344 cites W2096699969 @default.
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• W2912233344 cites W2130140789 @default.
• W2912233344 cites W2131053945 @default.
• W2912233344 cites W2137977071 @default.
• W2912233344 cites W2147569189 @default.
• W2912233344 cites W2148673266 @default.
• W2912233344 cites W2154248348 @default.
• W2912233344 cites W2165037395 @default.
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• W2912233344 cites W2226243673 @default.
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• W2912233344 doi "https://doi.org/10.1186/s12888-019-2026-6" @default.
• W2912233344 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6360727" @default.
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• W2912233344 hasPublicationYear "2019" @default.
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