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• W2912235874 abstract "Abstract Response surface methodology has been used to optimize the extraction conditions for total phenolics and carotenoids from leaves of Centella asiatica . Solvent concentration (30%–100%), extraction temperature (30–60°C), and extraction time (30–90 min) were used as the independent variables. A second‐order polynomial model produced a satisfactory fitting of the experimental data with regard to total phenolics ( R 2 = 84.75%, p < 0.004) and carotenoid ( R 2 = 78.74, p < 0.019) contents. The optimum extraction conditions of ethanol concentration, extraction temperature, and extraction time for phenolics were 6.1%, 70.2°C, and 110.5 min and for carotenoids, the optimum parameters were 100%, 70.2°C, and 110.5 min, respectively. The optimal predicted contents for total phenolics (9.03 mg Gallic Acid Equivalent ( GAE )/g DW ) and carotenoid (8.74 mg/g DW ) values in the extracts were agreed with the experimental values obtained with optimum extraction conditions for each response, and also they possess significantly higher total antioxidant capacity." @default.
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• W2912235874 date "2019-01-24" @default.
• W2912235874 modified "2023-10-16" @default.
• W2912235874 title "Response surface optimization for recovery of polyphenols and carotenoids from leaves of <i>Centella asiatica</i> using an ethanol‐based solvent system" @default.
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• W2912235874 doi "https://doi.org/10.1002/fsn3.832" @default.
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