Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912249583> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2912249583 endingPage "11477" @default.
- W2912249583 startingPage "11471" @default.
- W2912249583 abstract "Genetic studies on cancers have revealed that lncRNA-GAS5 and lncRNA-FAL1 are overexpressed in some cancerous cells. The aim of the present investigation was to evaluate the roles of lncRNA-GAS5 and lncRNA-FAL1 gene expression changes in the diagnosis and prognosis of patients with papillary thyroid carcinoma (PTC). In a case-control investigation, we recruited a total of 140 formalin-fixed paraffin-embedded tissues of PTC, including 70 cancerous and noncancerous tissues. Quantitative real-time polymerase chain reaction was used to determine the lncRNA-GAS5 and lncRNA-FAL1 level of gene expression in the two tissue groups. The association between the clinicopathological characteristics of patients and the expression level of lncRNA-GAS5 and lncRNA-FAL1 was evaluated. Our findings revealed that the level of expression in the lncRNA-GAS5 and lncRNA-FAL1 genes was significantly upregulated in thyroid cancerous tissues (P < 0.003 and P < 0.040, respectively). The expression of lncRNA-GAS5 and lncRNA-FAL1 revealed a significant association with tumor node metastasis staging (P < 0.042 and P < 0.001, respectively). It seems that the lncRNA-GAS5 and lncRNA-FAL1 genes play an oncogenic role in PTC. The two genes have a significant potential prognostic value and may likely be used as novel therapeutic targets for PTC patients in the future." @default.
- W2912249583 created "2019-02-21" @default.
- W2912249583 creator A5013818654 @default.
- W2912249583 creator A5075143422 @default.
- W2912249583 date "2019-02-11" @default.
- W2912249583 modified "2023-10-16" @default.
- W2912249583 title "Evaluation of prognostic usefulness of long noncoding RNA GAS5 and FAL1 in papillary thyroid carcinoma" @default.
- W2912249583 cites W1528730016 @default.
- W2912249583 cites W1848939527 @default.
- W2912249583 cites W1864729394 @default.
- W2912249583 cites W1987133441 @default.
- W2912249583 cites W1990273450 @default.
- W2912249583 cites W2027010998 @default.
- W2912249583 cites W2039816251 @default.
- W2912249583 cites W2052039819 @default.
- W2912249583 cites W2053255069 @default.
- W2912249583 cites W2054616484 @default.
- W2912249583 cites W2059631832 @default.
- W2912249583 cites W2067768332 @default.
- W2912249583 cites W2089630167 @default.
- W2912249583 cites W2099847894 @default.
- W2912249583 cites W2106787323 @default.
- W2912249583 cites W2156865223 @default.
- W2912249583 cites W2312782750 @default.
- W2912249583 cites W2323288618 @default.
- W2912249583 cites W2335029242 @default.
- W2912249583 cites W2573152477 @default.
- W2912249583 cites W2614101761 @default.
- W2912249583 cites W2614139220 @default.
- W2912249583 cites W2731847432 @default.
- W2912249583 cites W2750745381 @default.
- W2912249583 cites W2790164879 @default.
- W2912249583 cites W2809855188 @default.
- W2912249583 cites W2849369789 @default.
- W2912249583 cites W60325291 @default.
- W2912249583 doi "https://doi.org/10.1002/jcb.28425" @default.
- W2912249583 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30746742" @default.
- W2912249583 hasPublicationYear "2019" @default.
- W2912249583 type Work @default.
- W2912249583 sameAs 2912249583 @default.
- W2912249583 citedByCount "4" @default.
- W2912249583 countsByYear W29122495832019 @default.
- W2912249583 countsByYear W29122495832023 @default.
- W2912249583 crossrefType "journal-article" @default.
- W2912249583 hasAuthorship W2912249583A5013818654 @default.
- W2912249583 hasAuthorship W2912249583A5075143422 @default.
- W2912249583 hasConcept C104317684 @default.
- W2912249583 hasConcept C126322002 @default.
- W2912249583 hasConcept C127561419 @default.
- W2912249583 hasConcept C142724271 @default.
- W2912249583 hasConcept C150194340 @default.
- W2912249583 hasConcept C2776941990 @default.
- W2912249583 hasConcept C2993294228 @default.
- W2912249583 hasConcept C48023723 @default.
- W2912249583 hasConcept C49105822 @default.
- W2912249583 hasConcept C502942594 @default.
- W2912249583 hasConcept C526584372 @default.
- W2912249583 hasConcept C54355233 @default.
- W2912249583 hasConcept C62203573 @default.
- W2912249583 hasConcept C71924100 @default.
- W2912249583 hasConcept C86803240 @default.
- W2912249583 hasConceptScore W2912249583C104317684 @default.
- W2912249583 hasConceptScore W2912249583C126322002 @default.
- W2912249583 hasConceptScore W2912249583C127561419 @default.
- W2912249583 hasConceptScore W2912249583C142724271 @default.
- W2912249583 hasConceptScore W2912249583C150194340 @default.
- W2912249583 hasConceptScore W2912249583C2776941990 @default.
- W2912249583 hasConceptScore W2912249583C2993294228 @default.
- W2912249583 hasConceptScore W2912249583C48023723 @default.
- W2912249583 hasConceptScore W2912249583C49105822 @default.
- W2912249583 hasConceptScore W2912249583C502942594 @default.
- W2912249583 hasConceptScore W2912249583C526584372 @default.
- W2912249583 hasConceptScore W2912249583C54355233 @default.
- W2912249583 hasConceptScore W2912249583C62203573 @default.
- W2912249583 hasConceptScore W2912249583C71924100 @default.
- W2912249583 hasConceptScore W2912249583C86803240 @default.
- W2912249583 hasIssue "7" @default.
- W2912249583 hasLocation W29122495831 @default.
- W2912249583 hasLocation W29122495832 @default.
- W2912249583 hasOpenAccess W2912249583 @default.
- W2912249583 hasPrimaryLocation W29122495831 @default.
- W2912249583 hasRelatedWork W2009966535 @default.
- W2912249583 hasRelatedWork W2607515454 @default.
- W2912249583 hasRelatedWork W2614825660 @default.
- W2912249583 hasRelatedWork W2912249583 @default.
- W2912249583 hasRelatedWork W2948011254 @default.
- W2912249583 hasRelatedWork W2981288050 @default.
- W2912249583 hasRelatedWork W2991252237 @default.
- W2912249583 hasRelatedWork W3003836586 @default.
- W2912249583 hasRelatedWork W4220866825 @default.
- W2912249583 hasRelatedWork W4281778281 @default.
- W2912249583 hasVolume "120" @default.
- W2912249583 isParatext "false" @default.
- W2912249583 isRetracted "false" @default.
- W2912249583 magId "2912249583" @default.
- W2912249583 workType "article" @default.