FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912255273> ?p ?o ?g. }

• W2912255273 endingPage "9" @default.
• W2912255273 startingPage "1" @default.
• W2912255273 abstract "O uso dos inibidores da tirosina cínase (ITC) para o tratamento da leucemia mieloide crónica alterou significativamente o prognóstico dessa doença e permitiu uma esperança de vida praticamente normal. Apesar dos seus inegáveis benefícios, o uso dos ITC está associado a um aumento do risco de efeitos colaterais sobre o sistema cardiovascular, nomeadamente no risco de eventos aterotrombóticos. Torna‐se por isso necessário conhecer e prevenir os efeitos adversos desses fármacos de modo a permitir a continuação da terapêutica antileucémica e minimizar a toxidade para os doentes. Este documento multidisciplinar, elaborado através de uma colaboração entre hematologistas e cardiologistas de vários serviços hospitalares portugueses, tem por objetivo rever a toxidade cardiovascular associada aos vários ITCs e estabelecer sugestões para o seguimento desses doentes. São ainda propostas medidas para a avaliação e redução do risco cardiovascular desses doentes, critérios de referenciação e discutidas interações medicamentosas relevantes. The use of tyrosine kinase inhibitors (TKIs) for the treatment of chronic myeloid leukemia has significantly altered the prognosis of this disease, enabling close to normal life expectancy. Despite their undeniable benefits, the use of TKIs is associated with an increased risk of side effects on the cardiovascular system, particularly of atherothrombotic events. It is therefore necessary to understand and prevent the adverse effects of these drugs, in order to enable antileukemic therapy to continue and to minimize patients’ toxic exposure. This multidisciplinary consensus document, developed through a collaboration between hematologists and cardiologists, aims to review the cardiovascular toxicity associated with various TKIs and to establish recommendations for the follow‐up of these patients. Measures are also proposed for the assessment and reduction of cardiovascular risk in these patients and referral criteria, and relevant drug interactions are discussed." @default.
• W2912255273 created "2019-02-21" @default.
• W2912255273 creator A5011138146 @default.
• W2912255273 creator A5017367979 @default.
• W2912255273 creator A5019030595 @default.
• W2912255273 creator A5031484534 @default.
• W2912255273 creator A5052287429 @default.
• W2912255273 creator A5059081101 @default.
• W2912255273 creator A5059830495 @default.
• W2912255273 creator A5077564755 @default.
• W2912255273 creator A5090175765 @default.
• W2912255273 date "2019-01-01" @default.
• W2912255273 modified "2023-10-15" @default.
• W2912255273 title "Novas perspetivas para a abordagem dos efeitos cardiovasculares dos inibidores da tirosinacinase em doentes com leucemia mieloide crónica" @default.
• W2912255273 cites W1545265945 @default.
• W2912255273 cites W1814874339 @default.
• W2912255273 cites W1970962784 @default.
• W2912255273 cites W1971423532 @default.
• W2912255273 cites W1977996924 @default.
• W2912255273 cites W1991508660 @default.
• W2912255273 cites W1994279776 @default.
• W2912255273 cites W1998406030 @default.
• W2912255273 cites W1998990808 @default.
• W2912255273 cites W2011186694 @default.
• W2912255273 cites W2016773699 @default.
• W2912255273 cites W2034303883 @default.
• W2912255273 cites W2093608520 @default.
• W2912255273 cites W2097799776 @default.
• W2912255273 cites W2107268345 @default.
• W2912255273 cites W2115626434 @default.
• W2912255273 cites W2119010176 @default.
• W2912255273 cites W2130054182 @default.
• W2912255273 cites W2140259730 @default.
• W2912255273 cites W2143939343 @default.
• W2912255273 cites W2168411181 @default.
• W2912255273 cites W2168782870 @default.
• W2912255273 cites W2258178934 @default.
• W2912255273 cites W2296398034 @default.
• W2912255273 cites W2343511371 @default.
• W2912255273 cites W2402599050 @default.
• W2912255273 cites W2516537857 @default.
• W2912255273 cites W3021842026 @default.
• W2912255273 doi "https://doi.org/10.1016/j.repc.2017.10.013" @default.
• W2912255273 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30686651" @default.
• W2912255273 hasPublicationYear "2019" @default.
• W2912255273 type Work @default.
• W2912255273 sameAs 2912255273 @default.
• W2912255273 citedByCount "1" @default.
• W2912255273 countsByYear W29122552732020 @default.
• W2912255273 crossrefType "journal-article" @default.
• W2912255273 hasAuthorship W2912255273A5011138146 @default.
• W2912255273 hasAuthorship W2912255273A5017367979 @default.
• W2912255273 hasAuthorship W2912255273A5019030595 @default.
• W2912255273 hasAuthorship W2912255273A5031484534 @default.
• W2912255273 hasAuthorship W2912255273A5052287429 @default.
• W2912255273 hasAuthorship W2912255273A5059081101 @default.
• W2912255273 hasAuthorship W2912255273A5059830495 @default.
• W2912255273 hasAuthorship W2912255273A5077564755 @default.
• W2912255273 hasAuthorship W2912255273A5090175765 @default.
• W2912255273 hasBestOaLocation W29122552731 @default.
• W2912255273 hasConcept C126322002 @default.
• W2912255273 hasConcept C197934379 @default.
• W2912255273 hasConcept C29456083 @default.
• W2912255273 hasConcept C71924100 @default.
• W2912255273 hasConceptScore W2912255273C126322002 @default.
• W2912255273 hasConceptScore W2912255273C197934379 @default.
• W2912255273 hasConceptScore W2912255273C29456083 @default.
• W2912255273 hasConceptScore W2912255273C71924100 @default.
• W2912255273 hasIssue "1" @default.
• W2912255273 hasLocation W29122552731 @default.
• W2912255273 hasLocation W29122552732 @default.
• W2912255273 hasLocation W29122552733 @default.
• W2912255273 hasOpenAccess W2912255273 @default.
• W2912255273 hasPrimaryLocation W29122552731 @default.
• W2912255273 hasRelatedWork W1966939585 @default.
• W2912255273 hasRelatedWork W1980199008 @default.
• W2912255273 hasRelatedWork W1999344589 @default.
• W2912255273 hasRelatedWork W2374781999 @default.
• W2912255273 hasRelatedWork W2527805684 @default.
• W2912255273 hasRelatedWork W2748952813 @default.
• W2912255273 hasRelatedWork W2789448498 @default.
• W2912255273 hasRelatedWork W2885964272 @default.
• W2912255273 hasRelatedWork W2899084033 @default.
• W2912255273 hasRelatedWork W4236673861 @default.
• W2912255273 hasVolume "38" @default.
• W2912255273 isParatext "false" @default.
• W2912255273 isRetracted "false" @default.
• W2912255273 magId "2912255273" @default.
• W2912255273 workType "article" @default.