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- W2912260938 abstract "In 2012, a controversial study on the long-term toxicity of a Roundup herbicide and the glyphosate-tolerant genetically modified (GM) maize NK603 was published. The EC-funded G-TwYST research consortium tested the potential subchronic and chronic toxicity as well as the carcinogenicity of the glyphosate-resistant genetically modified maize NK603 by performing two 90-day feeding trials, one with GM maize inclusion rates of 11 and 33% and one with inclusion rates of up to 50%, as well as a 2-year feeding trial with inclusion rates of 11 and 33% in male and female Wistar Han RCC rats by taking into account OECD Guidelines for the testing of chemicals and EFSA recommendations on the safety testing of whole-food/feed in laboratory animals. In all three trials, the NK603 maize, untreated and treated once with Roundup during its cultivation, and the conventional counterpart were tested. Differences between each test group and the control group were evaluated. Equivalence was assessed by comparing the observed difference to differences between non-GM reference groups in previous studies. In case of significant differences, whether the effects were dose-related and/or accompanied by changes in related parameters including histopathological findings was evaluated. It is concluded that no adverse effects related to the feeding of the NK603 maize cultivated with or without Roundup for up to 2 years were observed. Based on the outcome of the subchronic and combined chronic toxicity/carcinogenicity studies, recommendations on the scientific justification and added value of long-term feeding trials in the GM plant risk assessment process are presented." @default.
- W2912260938 created "2019-02-21" @default.
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- W2912260938 date "2019-02-12" @default.
- W2912260938 modified "2023-10-15" @default.
- W2912260938 title "Lack of adverse effects in subchronic and chronic toxicity/carcinogenicity studies on the glyphosate-resistant genetically modified maize NK603 in Wistar Han RCC rats" @default.
- W2912260938 cites W1512733937 @default.
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- W2912260938 cites W2097214667 @default.
- W2912260938 cites W2103810083 @default.
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- W2912260938 cites W2125541785 @default.
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- W2912260938 cites W2531936635 @default.
- W2912260938 cites W2533248612 @default.
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- W2912260938 cites W2569425428 @default.
- W2912260938 cites W2594299258 @default.
- W2912260938 cites W2760405748 @default.
- W2912260938 cites W2896598694 @default.
- W2912260938 cites W2911621024 @default.
- W2912260938 cites W2912088947 @default.
- W2912260938 cites W2913806638 @default.
- W2912260938 cites W2914006725 @default.
- W2912260938 cites W2914573587 @default.
- W2912260938 cites W2914631756 @default.
- W2912260938 cites W2968732855 @default.
- W2912260938 cites W4214757067 @default.
- W2912260938 cites W4232113483 @default.
- W2912260938 cites W4233011843 @default.
- W2912260938 cites W4233625704 @default.
- W2912260938 cites W4235131617 @default.
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- W2912260938 doi "https://doi.org/10.1007/s00204-019-02400-1" @default.
- W2912260938 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7645492" @default.
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- W2912260938 hasPublicationYear "2019" @default.